| Roundhill Communications Ltd | Professional & scientific | 2014 |
| Rpem Empire Limited | Wholesale & retail | 2026 |
| RPM Training Group Ltd | Other services | 2022 |
| RS Motors Bristol Ltd | Wholesale & retail | 2025 |
| Rscb Building & Roofing Ltd | Construction | 2023 |
| Safety Horizon (South West) Ltd | Professional & scientific | 2012 |
| Sam's Woof Wash Limited | Other services | 2024 |
| Samurai Associates Limited | Construction | 2009 |
| Saphier Property & Maintenance Management Limited | Real estate | 2022 |
| Scott - Law Limited | Wholesale & retail | 1996 |
| Scott Group Holdings Limited | Financial services | 2021 |
| Sea Fuels Limited | Wholesale & retail | 2017 |
| Seabrew International Limited | Professional & scientific | 2018 |
| Sealey Land Developments Limited | Real estate | 2008 |
| Sebrina Properties Limited | Real estate | 2025 |
| SEF Investments Limited | Real estate | 2023 |
| Selenos Limited | Health & social care | 2022 |
| Severn View Developments Ltd | Construction | 2020 |
| Severn View Estates Ltd | Real estate | 2025 |
| Severnside School of Motoring Ltd | Education | 2026 |
| Seymore Consulting Limited | Health & social care | 2014 |
| Sharpness Community Swimming Trust | Arts & recreation | 2015 |
| Sharpness Shipyard and DRY Dock Limited | Manufacturing | 2000 |
| Sianya Limited | Manufacturing | 2003 |
| Sight Centres Hearing Limited | Health & social care | 1997 |
| Sistema Samco Ltd | Wholesale & retail | 2022 |
| SJR Skin & Wellness Ltd | Other services | 2025 |
| Skylark Adventures Ltd | Education | 2017 |
| Skylark Plus Limited | Education | 2022 |
| Skylark Transport Ltd | Transport & logistics | 2025 |
| Smiths Developments and Landscapes Limited | Construction | 2020 |
| SMW Maintenance & Building Ltd | Construction | 2012 |
| SO Barnes LLP | | 2025 |
| Sobk Bookkeeping Services Ltd | Professional & scientific | 2010 |
| Sobk Services Ltd | Wholesale & retail | 2010 |
| Sodbury Innovations Limited | Other services | 2023 |
| Sodbury Vale Day Nursery Limited | Education | 2006 |
| Sorori Design Events Limited | Other services | 2023 |
| Soukous Limited | Wholesale & retail | 2010 |
| Sounds Simple Limited | Information & communication | 2011 |
| South West Commercials Ltd | Wholesale & retail | 2011 |
| South West Heating and Plumbing Contractors Limited | Construction | 2010 |
| Southwood Consultancy Limited | Professional & scientific | 2024 |
| Spenic Converters LLP | | 2018 |
| Spenic Limited | Administrative & support | 2012 |
| Spetchley Estate Properties Limited | Construction | 2020 |
| Spetchley Gardens Enterprises Limited | Wholesale & retail | 2014 |
| Splicetek Communications Ltd | Construction | 2019 |
| Splicetek Holdings Limited | Professional & scientific | 2023 |
| Splicetek Utilities Limited | Information & communication | 2023 |
| SST Holdings Ltd | Financial services | 2023 |
| SSY Limited | Extraterritorial | 2011 |
| Stallard Business Consultancy Limited | Professional & scientific | 2011 |
| Stapleton Cricket Club Limited | Arts & recreation | 2024 |
| Starscan Services Ltd | Information & communication | 2010 |
| Stoke Gifford Garages Limited | Wholesale & retail | 2015 |
| Stone Heating Limited | Construction | 2017 |
| Stone With Woodford C of E Primary School | Education | 2013 |
| Strath Tirry Wind Energy Limited | Energy | 2020 |
| T J Jones Consulting Ltd | Professional & scientific | 2026 |
| T&K Management Ltd | Administrative & support | 2025 |
| T.R.Walsh Consultancy Ltd | Professional & scientific | 2020 |
| Tabletennisdaily Academy Limited | Education | 2017 |
| Tabletennisdaily Limited | Arts & recreation | 2020 |
| Tabletennisdaily Shop Limited | Education | 2017 |
| Tabletennisdaily Super League Limited | Arts & recreation | 2020 |
| Tallim Aerotech Limited | Manufacturing | 2002 |
| Taylormade Recycling & Waste Solutions Limited | Professional & scientific | 2013 |
| TBT Recovery and Transport Limited | Transport & logistics | 2022 |
| TED Aviation Limited | Manufacturing | 2024 |
| THE Berkeley Bakery Ltd | Hospitality | 2017 |
| THE Berkeley Community Sports & Leisure Trust | Arts & recreation | 2007 |
| THE Berkeley Hunt Limited | Administrative & support | 2005 |
| THE Boys WHO SEW Ltd | Manufacturing | 2021 |
| THE Brand in a Box Company Ltd | Administrative & support | 2004 |
| THE Bridal Rotation Limited | Wholesale & retail | 2025 |
| THE Celebration Roadshow Limited | Arts & recreation | 2014 |
| THE Clever Studio Limited | Professional & scientific | 2020 |
| THE Coaching Movement Limited | Professional & scientific | 2023 |
| THE Computer Store Ltd | Wholesale & retail | 2018 |
| THE Family Trade Engravers Limited | Information & communication | 2016 |
| THE FIX IT Shop Ltd | Wholesale & retail | 2023 |
| THE HAM Brewing Company Limited | Manufacturing | 2015 |
| THE Hydroponics Company Limited | Manufacturing | 2016 |
| THE Perfect Blend Berkeley Ltd | Hospitality | 2022 |
| THE Pottery Shed Limited | Arts & recreation | 2023 |
| THE Scott-Law Properties LLP | | 2002 |
| THE Wright Retreat Ltd | Hospitality | 2018 |
| Thornbury Cleaning Company Limited | Administrative & support | 2005 |
| Thornbury MX Limited | Wholesale & retail | 2005 |
| Thornbury MX Club Events Limited | Arts & recreation | 2025 |
| Tiley's Brewery Limited | Hospitality | 2013 |
| Tilly and Family Ltd | Wholesale & retail | 2021 |
| Tori Properties Limited | Real estate | 2012 |
| Trail Stitch Ltd | Wholesale & retail | 2026 |
| Transport Electrical Limited | Wholesale & retail | 2023 |
| Treecreeper Arborists Ltd | Agriculture & fishing | 2011 |
| Trendmarket Ltd | Wholesale & retail | 2024 |
| Trent's Foods Ltd | Wholesale & retail | 2018 |
| Triple Seven Limited | Manufacturing | 2007 |