| Secure Scaffolding Ltd | Construction | 2024 |
| Senior Relief Company Ltd | Wholesale & retail | 2025 |
| SF Exclusives Limited | Wholesale & retail | 2025 |
| Shamak Services Limited | Health & social care | 2021 |
| Shamma Education Training and Services Ltd | Education | 2010 |
| Shanu Omole Consulting Ltd | Information & communication | 2016 |
| Sharon Care Agency Ltd | Health & social care | 2017 |
| Shergill Drywall Ltd | Construction | 2026 |
| Sherisesyouth CIC | Education | 2025 |
| Shiny Maintenance Ltd | Other services | 2017 |
| Shiva AUM Limited | Wholesale & retail | 2018 |
| Shoshi Industry Limited | Manufacturing | 2022 |
| SHY Productions Ltd | Arts & recreation | 2020 |
| Silva Group Software Ltd | Information & communication | 2025 |
| Silver Stone Trading Limited | Construction | 2021 |
| Silver Vale Estates Ltd | Real estate | 2025 |
| Silwood Space Ltd | Construction | 2022 |
| Singhs Builders Limited | Professional & scientific | 2018 |
| Siva Smarts Move Ltd | Construction | 2022 |
| SJD Hub Limited | Professional & scientific | 2025 |
| SKP Medical Supplies Ltd. | Wholesale & retail | 2014 |
| Skye Corp Limited | Wholesale & retail | 2015 |
| Skyfall VR Ltd | Hospitality | 2021 |
| Slow Mornings Ltd | Hospitality | 2026 |
| SLR Auto Centre Limited | Wholesale & retail | 2020 |
| SLS Sweepers Ltd | Administrative & support | 2024 |
| Smart Fixer Construction Ltd | Construction | 2019 |
| Smartistic Ltd | Transport & logistics | 2018 |
| Smartway Entertainment Limited | Information & communication | 2015 |
| Smashh House Ltd | Hospitality | 2026 |
| Smee Building Services Ltd | Construction | 2022 |
| SMU Investments Limited | Real estate | 2025 |
| Sohab Limited | Health & social care | 2023 |
| Soko Services Limited | Wholesale & retail | 2024 |
| Solid Music Academy CIC | Education | 2026 |
| Solid Music Mastery Ltd | Education | 2026 |
| Solis Systems Ltd | Wholesale & retail | 2025 |
| Sooa Limited | Administrative & support | 2016 |
| Sooch Estates Limited | Real estate | 2017 |
| South East London Roofing Ltd | Construction | 2026 |
| South East Solar Systems Limited | Energy | 2025 |
| SOW Theatre Group Limited | Arts & recreation | 2023 |
| Space Properties (London) Ltd | Real estate | 2024 |
| Sparky Brooks Ltd | Construction | 2019 |
| Special Care 4 U Ltd | Health & social care | 2020 |
| Spectrum Electrics Limited | Manufacturing | 2015 |
| Speedy Delivery Limited | Transport & logistics | 2019 |
| Spin DRY Services Ltd | Other services | 2011 |
| Spruce Cleaning Limited | Administrative & support | 2018 |
| Squid Shack Studios Ltd | Information & communication | 2020 |
| SRM Residential Enterprises Limited | Real estate | 2023 |
| SRM Residential Limited | Real estate | 2020 |
| SRS Builders and Plumbing Ltd | Construction | 2020 |
| Ssamz Cleaning Ltd | Wholesale & retail | 2024 |
| SSN Property Group Ltd | Financial services | 2025 |
| Stallion Building Services Limited | Administrative & support | 1995 |
| Starbrandz Ltd | Construction | 2024 |
| Starskinuk L Ltd | Other services | 2026 |
| Stepping Stone Abode Ltd | Health & social care | 2024 |
| Stone & Ceramic Belvedere Limited | Construction | 2023 |
| Stone & Ceramic Fabrication Ltd | Construction | 2023 |
| Stone & Ceramic Group Limited | Construction | 2023 |
| Stone & Ceramic Holdings Limited | Construction | 2023 |
| Stone & Ceramic Limited | Construction | 1995 |
| Stone & Ceramic London Limited | Construction | 2023 |
| Stone & Ceramic Projects Limited | Construction | 2023 |
| Stone & Ceramic Services Limited | Construction | 2023 |
| Stone & Ceramic Shop Limited | Construction | 2023 |
| Stone & Ceramic Store Limited | Construction | 2023 |
| Stone & Ceramic Supplies Limited | Construction | 2023 |
| Stone & Ceramic Tiling Limited | Construction | 2023 |
| Stone & Ceramic Worktops Ltd | Construction | 2023 |
| Stonebridge Property Holdings Ltd | Real estate | 2024 |
| Strahlung Innovation & Enterprise Group (Sieg) Ltd. | Professional & scientific | 2011 |
| Stratamon Limited | Information & communication | 2023 |
| Strategic Advisory & Management Ltd | Administrative & support | 2019 |
| Studify Education Limited | Administrative & support | 2025 |
| Sukhvinder Singh Ltd | Construction | 2025 |
| Sunira Aesthetics Ltd | Other services | 2023 |
| Sunnydaze Ltd | Other services | 2020 |
| Sunshine Cafe (Kent) Limited | Hospitality | 2016 |
| Super E Twins Limited | Wholesale & retail | 2022 |
| Supreme Trophies Limited | Arts & recreation | 2024 |
| SV Carpathian Ltd | Construction | 2024 |
| Sweatpro Ltd | Wholesale & retail | 2022 |
| Swift London Car Services Ltd | Administrative & support | 2025 |
| Swordfish Communications Limited | Professional & scientific | 2000 |
| Syed Group UK Holdings Limited | Financial services | 2024 |
| Syed MH Properties Limited | Real estate | 2024 |
| Syed Paribahan UK Limited | Transport & logistics | 2024 |
| Synatel Training Ltd | Administrative & support | 2017 |
| T Murape Courier Limited | Transport & logistics | 2015 |
| T-Grace Global Tourism & Events Ltd | Administrative & support | 2025 |
| Tagsure Products Limited | Manufacturing | 2026 |
| Tagsure Safety Ltd | Professional & scientific | 2026 |
| TAJ & TEG Constructions Ltd | Construction | 2023 |
| TAJ Auto Repair Centre Ltd | Wholesale & retail | 2018 |
| Talking Therapy Clinic Ltd | Health & social care | 2017 |
| Tano Design Limited | Professional & scientific | 2018 |
| Tasty Excel Limited | Manufacturing | 2026 |