| Dyadey Limited | Information & communication | 2014 |
| Dylan Oaks International Limited | Wholesale & retail | 2023 |
| Dylex Software Ltd | Information & communication | 2015 |
| Dynamic E-Services Limited | Wholesale & retail | 2020 |
| Dynamic Seares Limited | Wholesale & retail | 2025 |
| Dynamic Trading (N.I.) Ltd | Financial services | 2023 |
| Dynamite Consulting Ltd | Professional & scientific | 2020 |
| Dynamite Lifestyle Limited | Professional & scientific | 2017 |
| Dynamite Properties Limited | Households | 2019 |
| Dynan Medical Services Ltd | Health & social care | 2022 |
| Dynasty Estate Investments Limited | Real estate | 2025 |
| Dynes Holdings Limited | Financial services | 2020 |
| Dynes Residential Limited | Real estate | 2003 |
| Déan É CIC | Real estate | 2024 |
| Dúchas Oiriall Ltd | Arts & recreation | 2017 |
| E & G Casa Ltd | Real estate | 2021 |
| E & G Upholstery Ltd | Other services | 2022 |
| E a Oven & Appliance Cleaning Limited | Manufacturing | 2016 |
| E Burns Communications Limited | Wholesale & retail | 2015 |
| E Davenport Consultancy Services Limited | Professional & scientific | 2019 |
| E First Ltd | Wholesale & retail | 2024 |
| E Flynn Building Contractors Ltd | Construction | 2017 |
| E Flynn Car Sales Ltd | Wholesale & retail | 2017 |
| E Global Cart Ltd | Wholesale & retail | 2026 |
| E Grid Services Limited | Energy | 2023 |
| E Irvine Enterprises Limited | Wholesale & retail | 1996 |
| E L Gillan Ltd | Wholesale & retail | 2010 |
| E M (2018) Ltd | Wholesale & retail | 2018 |
| E M Gray & Co Ltd | Financial services | 2010 |
| E Propulsion Systems Limited | Wholesale & retail | 2025 |
| E T Turnbull Ltd | Wholesale & retail | 2023 |
| E&D Consultants Limited | Professional & scientific | 2024 |
| E&M Construction Supplies Ltd | Wholesale & retail | 2025 |
| E-Convinience Store Ltd | Wholesale & retail | 2025 |
| E-Direct International Trading Limited | Wholesale & retail | 2025 |
| E-Golfireland Ltd | Information & communication | 2011 |
| E-Learning Training and Development Limited | Education | 2013 |
| E-Wanta Limited | Wholesale & retail | 2009 |
| E. Connolly (Publicans) Limited | Hospitality | 1981 |
| E.A. Lonergan Ltd | Real estate | 1993 |
| E.E.G Trading Ltd | Manufacturing | 2020 |
| E.K. Fuels (NI) Limited | Wholesale & retail | 2016 |
| E.Laurenson Plumbing & Heating Ltd | Construction | 2019 |
| E.Y Media & Publishing Limited | Information & communication | 2022 |
| E.Y Solutions Ltd | Information & communication | 2026 |
| Ea-Rs Solutions Ireland Limited | Professional & scientific | 2025 |
| EAD17 Ltd | Extraterritorial | 2017 |
| Eagle Future Limited | Households | 2025 |
| Eagle Power Solutions Ltd | Energy | 2019 |
| Eagle Star House NI Ltd | Real estate | 2024 |
| Eagle Wing Productions Limited | Administrative & support | 2023 |
| Eaglepass Limited | Construction | 1987 |
| Eaglepass Properties Limited | Real estate | 2011 |
| Eagles Mechanical Ltd | Construction | 2025 |
| Eagleton Hall Ltd | Households | 2012 |
| Eala Croí Ltd | Other services | 2026 |
| Eamonn Caldwell Ltd | Wholesale & retail | 2025 |
| Eamundo Ltd | Hospitality | 2025 |
| Earlston Mews Management Company Limited | Households | 2006 |
| Earlswood Management Co Limited | Households | 1983 |
| Earlwood Designs PTY Ltd | Wholesale & retail | 2026 |
| Early Learners Day Nursery Limited | Health & social care | 2011 |
| Early Years - the Organisation for Young Children | Other services | 1989 |
| Early Years Boutique Ltd | Wholesale & retail | 2012 |
| Early Years Company Limited - the | Health & social care | 1999 |
| Easca Mattress Ltd | Wholesale & retail | 2016 |
| Easi Fuels Ltd | Wholesale & retail | 2025 |
| Easibuild.Com Ltd | Information & communication | 2002 |
| Easilocks N.I Limited | Other services | 2025 |
| Easl Limited | Professional & scientific | 2005 |
| Eason Electronic International Limited | Information & communication | 1969 |
| Eassda (Bush Road Antrim) Limited | Construction | 2010 |
| Eassda (Bushforde Road) Limited | Construction | 2010 |
| Eassda (Lindara) Limited | Construction | 2010 |
| East (NO1) Limited | Financial services | 2019 |
| East Belfast Alternatives Limited | Health & social care | 2004 |
| East Belfast Arts Collective | Arts & recreation | 1997 |
| East Belfast Community Development Agency | Administrative & support | 1996 |
| East Belfast Enterprise Ltd | Administrative & support | 1989 |
| East Belfast Independent Advice Centre | Other services | 2001 |
| East Belfast Management Company Limited | Households | 2024 |
| East Belfast Mission Trading Limited | Other services | 1991 |
| East Belfast Sure Start | Education | 2001 |
| East Coast F&C (N.I.) Ltd | Wholesale & retail | 2024 |
| East Down Education Partnership (Holdings) Limited | Financial services | 2007 |
| East Down Education Partnership Limited | Financial services | 2006 |
| East END Baptist Church Limited | Other services | 1987 |
| East END Kebab House Ltd | Hospitality | 2020 |
| East Engineering Ltd | Manufacturing | 2023 |
| East House Belfast Ltd | Hospitality | 2024 |
| East MON Takeaway Ltd | Hospitality | 2025 |
| East Shore Social Limited | Construction | 2022 |
| East-Trade System LP | | 2017 |
| Eastar Solution Co Limited | Wholesale & retail | 2026 |
| Eastleigh Investments Limited | Real estate | 2023 |
| Eastlink Properties Ltd | Real estate | 2025 |
| Eastonville Investments Limited | Real estate | 2014 |
| Eastonville Limited | Construction | 2009 |
| Eastonville Loans Limited | Real estate | 2014 |
| Eastonville Traders Limited | Construction | 1984 |