| PS Inns Limited | Hospitality | 2021 |
| Pulsibaby Ltd | Manufacturing | 2019 |
| R Dolman Limited | Extraterritorial | 2004 |
| R W Nelson Limited | Professional & scientific | 2010 |
| Rarb Limited | Professional & scientific | 2009 |
| Reach Investment Properties Ltd | Real estate | 2019 |
| Red Sail Games Ltd | Information & communication | 2012 |
| Rendezvous (Hairdressing Supplies) Limited | Wholesale & retail | 1976 |
| Resultadarrojado Limited | Financial services | 2026 |
| Rocco and Sons Limited | Construction | 2001 |
| Rs&B Builders Limited | Construction | 2025 |
| Rylands Court Management Company Limited | Administrative & support | 1981 |
| Salt and Care Limited | Construction | 2022 |
| Sheetfabs (Nottingham) Limited | Manufacturing | 1946 |
| Short Interiors Limited | Construction | 2000 |
| Shoulder Care Ltd | Administrative & support | 2016 |
| Slim and Smart Ltd | Manufacturing | 2016 |
| Smhs Ltd | Information & communication | 2008 |
| SMS Product Services Limited | Manufacturing | 2007 |
| SOE Health Limited | Manufacturing | 2010 |
| Steven Christopher Design Ltd | Construction | 2006 |
| T and J Electrical Labour Services Ltd | Manufacturing | 2013 |
| T Fryer Electrical Limited | Construction | 2024 |
| T&J Holmes Limited | Real estate | 2019 |
| Tecl Holdings Limited | Real estate | 2012 |
| TF Project Services Ltd | Information & communication | 2020 |
| TGC Ventures Ltd | Water & waste | 2017 |
| THE Gateshead Town Centre Partnership | | 1999 |
| THE HOO Cottage Ltd | Real estate | 2019 |
| TOP5 Consultancy Limited | Wholesale & retail | 2022 |
| UA Services Ltd | Health & social care | 2015 |
| Vytaminf Ltd | Financial services | 2025 |
| Webs Training Limited | Education | 1988 |
| Wicked Haze Ltd | Wholesale & retail | 2025 |
| Youth Education Support (YES) | Education | 2009 |