| DEE Accounting Limited | Professional & scientific | 2015 |
| Deep END Pools Ltd | Construction | 2001 |
| Delta Uniform November Charlie Ltd | Construction | 2025 |
| Deltaoak Limited | Administrative & support | 1997 |
| Demiart Limited | Construction | 1988 |
| Denmead Property Partners Limited | Real estate | 2024 |
| Dent Mind Ltd | Education | 2023 |
| Dentico Dental Agency Ltd | Administrative & support | 2020 |
| Depad Studio Ltd | Information & communication | 2023 |
| Depg Ltd | Construction | 2024 |
| Derhine Ltd | Health & social care | 2022 |
| Descant Developments Ltd | Real estate | 2021 |
| Design SET Ltd | Wholesale & retail | 2021 |
| Deswik Europe Limited | Administrative & support | 2011 |
| Develoe Limited | Real estate | 2023 |
| Devenex Limited | Information & communication | 2026 |
| Deveron Property Holdings Ltd | Real estate | 2025 |
| Dezrez Mortgages Limited | Financial services | 2006 |
| Diamond Style (UK) Limited | Wholesale & retail | 2013 |
| Diamondworldclothing Ltd | Wholesale & retail | 2025 |
| Digital E-Marketing Ltd | Professional & scientific | 2017 |
| Dijiwerx Ltd | Information & communication | 2010 |
| Dinas Accounting Services Ltd | Professional & scientific | 2019 |
| Dineen Consulting Limited | Information & communication | 1999 |
| Direct Cover Limited | Professional & scientific | 2002 |
| Directstone Limited | Construction | 2005 |
| Discovery Life Sciences (UK) Limited | Professional & scientific | 2019 |
| Disraeli House Property Limited | Real estate | 2013 |
| Ditty Box Ltd | Information & communication | 2002 |
| Diving Services UK Limited | Administrative & support | 2005 |
| Divyanga Ltd | Information & communication | 2014 |
| DIY Simple Ltd | Wholesale & retail | 2025 |
| Dmsconsult (UK) Ltd | Construction | 2013 |
| DN Business Solutions Limited | Information & communication | 2009 |
| DN Commercial Ltd | Health & social care | 2023 |
| DN Investment Solutions Limited | Real estate | 2021 |
| DN Webber Consulting Limited | Health & social care | 2013 |
| Dobash Realty Enterprises International Limited | Construction | 2024 |
| Doctor NOW Limited | Health & social care | 2004 |
| Doctor NOW Occupational Health Limited | Health & social care | 2019 |
| Doctors NOW Limited | Health & social care | 2013 |
| Docuplus Limited | Other services | 1998 |
| Dominion Designers Limited | Professional & scientific | 2002 |
| Domvs London (Avenue Road) Limited | Construction | 2021 |
| Domvs London (Global Holdings) Limited | Real estate | 2016 |
| Domvs London Limited | Real estate | 2010 |
| Donoghue Consulting Limited | Professional & scientific | 2000 |
| Doodlebug Multimedia Ltd. | Professional & scientific | 2008 |
| Dormant Company 06373490 Unlimited | | 2007 |
| Double Quick Marketing Limited | Real estate | 2003 |
| Double Yolk Design Ltd | Information & communication | 2009 |
| Doug Drewett & Sons Limited | Wholesale & retail | 2007 |
| Douglas Commercial Consulting Limited | Professional & scientific | 2008 |
| DR DAD Limited | Health & social care | 2022 |
| DR N Rahman Ltd | Health & social care | 2022 |
| DR P Ramrakha Limited | Health & social care | 2003 |
| DR SJT Executive Medical Affairs Consultancy Ltd | Professional & scientific | 2024 |
| Drag Medical Ltd | Health & social care | 2014 |
| Dragoman Language Solutions Limited | Information & communication | 2014 |
| Drainaway Ltd | Professional & scientific | 2022 |
| Drcg Business Services Ltd | Professional & scientific | 2021 |
| Dreamvar (UK) Limited | Real estate | 2013 |
| Dreamz Entertainment Private Limited | Information & communication | 2025 |
| Drentsoft Games Ltd | Manufacturing | 2021 |
| Drinks That Deliver Limited | Wholesale & retail | 2020 |
| Drissell Consulting Ltd | Public administration | 2025 |
| Drogon Property Company Limited | Real estate | 2021 |
| Drova Limited | Professional & scientific | 2012 |
| DS Asset Investments Ltd | Real estate | 2024 |
| DS Cleaning Solutions Limited | Administrative & support | 2022 |
| DS4 Ltd | Professional & scientific | 2016 |
| DSL Construction and Rigging Ltd | Construction | 2025 |
| DU Group Ltd | Other services | 2018 |
| Duck Consulting Ltd | Professional & scientific | 2022 |
| Ducky Investments Ltd | Professional & scientific | 2021 |
| Ducorp Capital Limited | Real estate | 2009 |
| Dukeswood Limited | Construction | 2018 |
| Dundas Holdings Limited | Real estate | 2019 |
| Duress UK Ltd | Information & communication | 2025 |
| Dusk IT Solutions Limited | Administrative & support | 2016 |
| Dustylane Limited | Real estate | 1996 |
| DW Operations & Management Consulting Services Ltd | Professional & scientific | 2025 |
| Dwir Limited | Wholesale & retail | 2020 |
| Dynamic Labour Limited | Construction | 2022 |
| Dynamism Europe Limited | Wholesale & retail | 2012 |
| Dyntec Limited | Professional & scientific | 2023 |
| E D F M (UK) Limited | Other services | 2011 |
| E6 Ltd | Professional & scientific | 2010 |
| EAB Construction Limited | Construction | 2021 |
| EAB Homes & Developments Ltd | Extraterritorial | 2017 |
| EAB Homes Ltd | Construction | 2011 |
| EAD Marketing Limited | Professional & scientific | 2013 |
| Earlier on Ltd | Professional & scientific | 2024 |
| Easa European & World Chapter Limited | Administrative & support | 2009 |
| Eastbury Design & Build Ltd | Construction | 2021 |
| Easy Karaoke Ltd | Manufacturing | 2000 |
| Eatin Limited | Hospitality | 2024 |
| Eclipse Inventories Limited | Real estate | 2010 |
| Eco Chameleon Home Restoration Ltd | Other services | 2015 |
| Ecoinsect Limited | Agriculture & fishing | 2016 |