| SP Techno Solutions Ltd | Information & communication | 2011 |
| Space Monkey Limited | Professional & scientific | 2023 |
| Sparkle Lighting Limited | Wholesale & retail | 2020 |
| Sparkling Spaces Cleaning Services Limited | Administrative & support | 2025 |
| Sparta Homes Limited | Real estate | 2017 |
| Speech Therapy Consultants Limited | Health & social care | 2024 |
| Speedskim Limited | Wholesale & retail | 2012 |
| Spencer Property Investments Limited | Real estate | 2016 |
| SPH 2020 Limited | Financial services | 2020 |
| SPH2 Limited | Construction | 2024 |
| Spider Flooring Limited | Manufacturing | 2020 |
| Spider Resin Limited | Manufacturing | 2022 |
| Spill the T Media Ltd | Professional & scientific | 2022 |
| Spinfield Investments 27 Ltd | Households | 2018 |
| Spinningfields Promotional Leisure Activities Limited | Arts & recreation | 2013 |
| Spirit YDC Limited | Arts & recreation | 2016 |
| Spooky Papas Limited | Arts & recreation | 2022 |
| Sport DU Monde (SDM) Limited | Professional & scientific | 2018 |
| Spring Corner 25 Consulting Limited | Professional & scientific | 2025 |
| Sprt Homes and Lettings Limited | Financial services | 2024 |
| Spudd Tools Ltd | Manufacturing | 2024 |
| Square Plumbing Limited | Construction | 2023 |
| Squidge Investments Limited | Real estate | 2018 |
| Squirrel Fixings Limited | Administrative & support | 2003 |
| SRB Labs Limited | Professional & scientific | 2025 |
| SRG Logistics and Services Ltd | Transport & logistics | 2019 |
| Srng Limited | Real estate | 2012 |
| SRV Capital Ltd | Real estate | 2024 |
| SSL Ascot Opco Ltd | Health & social care | 2018 |
| SSL Banstead Propco Ltd | Real estate | 2024 |
| SSL Bentley House Propco Ltd | Real estate | 2024 |
| SSL Caversham GP LLP | | 2022 |
| SSL Caversham Nominee Limited | Other services | 2022 |
| SSL Caversham Opco LP | | 2022 |
| SSL Coombe Propco Ltd | Real estate | 2024 |
| SSL Enfield Opco Ltd | Real estate | 2024 |
| SSL Enfield Propco Ltd | Real estate | 2024 |
| SSL Farnham Common GP LLP | | 2022 |
| SSL Farnham Common Nominee Limited | Other services | 2022 |
| SSL Farnham Common Opco LP | | 2022 |
| SSL Highgate GP LLP | | 2022 |
| SSL Highgate Nominee Limited | Other services | 2022 |
| SSL Highgate Opco LP | | 2022 |
| SSL Hornchurch Opco Ltd | Real estate | 2024 |
| SSL Hornchurch Propco Ltd | Real estate | 2024 |
| SSL Investment PIV Ltd | Financial services | 2024 |
| SSL Partners I LP | | 2010 |
| SSL Partners II, L.P. | | 2011 |
| SSL Partners III LP | | 2013 |
| SSL Partners IV LP | | 2019 |
| SSL Partners V LP | | 2019 |
| SSL Partners VI LP | | 2021 |
| SSL Surbiton Opco Ltd | Real estate | 2024 |
| SSL Surbiton Propco Ltd | Real estate | 2024 |
| SSL Weybridge Propco Ltd | Real estate | 2024 |
| Sspr Management Ltd | Real estate | 2021 |
| ST Jarna 72 Holdings Limited | Financial services | 2025 |
| ST Jarna 72 Limited | Financial services | 2020 |
| ST Swithins Developments Limited | Construction | 2008 |
| Stabilis Holding Company Limited | Real estate | 2016 |
| Stable Ventures Limited | Construction | 2019 |
| Staden Grange & Co Ltd | Hospitality | 2023 |
| Staffhost Group Limited | Financial services | 2022 |
| Staffhost Limited | Administrative & support | 2012 |
| Staging Post Limited | Administrative & support | 2023 |
| Stanleybell Investments Ltd | Households | 2021 |
| Stapleton Projects Ltd | Financial services | 2024 |
| Star & Lily Ltd | Wholesale & retail | 2021 |
| Star W11 Ltd | Other services | 2025 |
| Starboard Hotels Four LLP | | 2007 |
| Starboard Hotels Limited | Real estate | 2003 |
| Starboard Hotels One LLP | | 2006 |
| Starboard Hotels Two LLP | | 2007 |
| Starr Business Supplies Limited | Wholesale & retail | 2003 |
| Start Line Consulting Ltd | Administrative & support | 2015 |
| Statebrook Limited | Construction | 1969 |
| Stayinmyhouse Limited | Real estate | 2020 |
| Stead Global Ltd | Information & communication | 2025 |
| Steak Shell Ltd | Hospitality | 2021 |
| Stealthwatch Limited | Administrative & support | 2024 |
| Steeles Utility Services Limited | Other services | 2016 |
| Stinger Investments Limited | Real estate | 2019 |
| Stockley Fitness Services Limited | Arts & recreation | 2021 |
| Stockra Limited | Administrative & support | 2026 |
| Stoic Limited | Wholesale & retail | 2000 |
| Storemove Limited | Professional & scientific | 1999 |
| Storer Financial Planning Limited | Professional & scientific | 2012 |
| Storybook Property Limited | Administrative & support | 2015 |
| Strategic Solutions Group Limited | Professional & scientific | 2020 |
| Strategiis Ltd | Professional & scientific | 2017 |
| Stratton House Development Ltd | Construction | 2025 |
| Strawberrybombe Limited | Arts & recreation | 2019 |
| Strictly Shine Limited | Administrative & support | 2015 |
| String Hearts Ltd | Wholesale & retail | 2025 |
| Strive Capital LLP | | 2020 |
| Strive Investments Limited | Financial services | 2020 |
| Strive IT Services Limited | Extraterritorial | 2023 |
| Stubborn Heart Music Ltd | Information & communication | 2012 |
| Studio 51 Hair and Beauty Limited | Other services | 2023 |
| Studio EVH Ltd | Professional & scientific | 2022 |