| Salamander Pubs Ltd | Hospitality | 2017 |
| Salamander Trans Ltd | Transport & logistics | 2025 |
| Sales Skills Audit Limited | Professional & scientific | 2015 |
| Saleve Ltd | Real estate | 2023 |
| Salisbury Simms Limited | Wholesale & retail | 2025 |
| Sall - Sales and Lettings Limited | Real estate | 2017 |
| Sally Lunn's Limited | Hospitality | 2012 |
| Sally Muir Ltd | Arts & recreation | 2022 |
| Sally Narrowboats Limited | Administrative & support | 2008 |
| Sally Verney Limited | Financial services | 2015 |
| Salomon Whittle Limited | Professional & scientific | 2006 |
| Saltford Hair Ltd | Other services | 2012 |
| Saltford Kitchens Ltd | Wholesale & retail | 2018 |
| Salty Air Limited | Professional & scientific | 2006 |
| Salus (Bath) Limited | Real estate | 2025 |
| Salus Equity Ltd. | Financial services | 2025 |
| Salus GP LLP | | 2026 |
| Salus Intelligence Limited | Professional & scientific | 2012 |
| Salvum Investments Ltd | Water & waste | 2025 |
| SAM Baring Partnerships Ltd | Professional & scientific | 2020 |
| SAM Hofman Ltd | Professional & scientific | 2013 |
| Sambec Property Development Ltd | Construction | 2019 |
| Same Boat Parents Ltd | Other services | 2023 |
| Samler Landscapes Limited | Agriculture & fishing | 2003 |
| Samwells Limited | Administrative & support | 2005 |
| Samwells Properties Limited | Real estate | 2013 |
| Sana Capital Limited | Professional & scientific | 2022 |
| Sanabitur Limited | Professional & scientific | 2013 |
| Sanborn Consulting Limited | Information & communication | 1998 |
| Sanctuary Properties UK Ltd | Real estate | 2014 |
| Sanctum Ventures Ltd | Real estate | 2025 |
| Sandeman Estates Limited | Health & social care | 2018 |
| Sandhu Orthopaedics (Bath) Limited | Health & social care | 2018 |
| Sandstone Trading Ltd | Wholesale & retail | 2025 |
| Sandy Haven Solutions Ltd | Professional & scientific | 2021 |
| Sanelli Solutions Ltd | Construction | 2023 |
| Sani Property Ltd | Real estate | 2022 |
| Sanika Investments Limited | Real estate | 2018 |
| Sanity Ltd | Arts & recreation | 2018 |
| Sanremo the Italian Restaurant Ltd | Hospitality | 2023 |
| Sansdon Ltd | Wholesale & retail | 2025 |
| Sapien Consulting Ltd | Professional & scientific | 2025 |
| Sapient Commodities Ltd | Professional & scientific | 2024 |
| Sapient Consultants Limited | Professional & scientific | 2023 |
| Sapphic Pilates Ltd | Arts & recreation | 2025 |
| Sapphire Bidco Limited | Financial services | 2018 |
| Sapphire International Education Ltd | Education | 2025 |
| Saracen House Estates Limited | Real estate | 1972 |
| Sarafina FOX Ltd | Extraterritorial | 2022 |
| Sarah Cares (Bath) Limited | Health & social care | 2016 |
| Sarah Hickey Legal Services Limited | Professional & scientific | 2022 |
| Sarracenia Limited | Professional & scientific | 2002 |
| Sarthi UK Ltd | Professional & scientific | 2023 |
| Sarthi Ventures Ltd | Hospitality | 2025 |
| SAS (2018) Limited | Construction | 2018 |
| Sash & Stone Limited | Hospitality | 2024 |
| Satiee Ltd | Information & communication | 2026 |
| Satori Organisational Development Limited | Professional & scientific | 2025 |
| Satsooma Ltd | Construction | 2025 |
| Saul David Limited | Information & communication | 2007 |
| Saunders & Weeks (Bristol) Limited | Manufacturing | 1973 |
| Save Teachers' Sundays Limited | Education | 2014 |
| Saviety Consulting Limited | Professional & scientific | 2022 |
| Savv Healthcare Limited | Health & social care | 2022 |
| Saxbysurgical Limited | Health & social care | 2024 |
| SB Roofing South West Limited | Construction | 2024 |
| Sc&A Consultants Limited | Professional & scientific | 2022 |
| Scala Studios Ltd | Education | 2011 |
| Scalewell Limited | Information & communication | 2020 |
| Scan Check Systems Limited | Construction | 1998 |
| Scanda Springs (1996) Limited | Manufacturing | 1926 |
| Scarlett, Llewellyn and Rose Limited | Extraterritorial | 2019 |
| Scarper Tours Limited | Transport & logistics | 2013 |
| Scene Investigations Ltd | Professional & scientific | 2021 |
| Schischek Limited | Wholesale & retail | 1993 |
| Scholars Gate Ltd | Education | 2026 |
| School Channel Ltd | Education | 2020 |
| School Court (Bath) Management Company Limited | Households | 2007 |
| School Guide UK Limited | Information & communication | 2014 |
| Schulte and Loughborough Electro Systems Limited | Manufacturing | 1985 |
| Schwartz Brothers Limited | Hospitality | 1976 |
| Sci-Teq Limited | Information & communication | 1997 |
| Scidev Ltd | Professional & scientific | 2023 |
| SCK Education Ltd | Education | 2017 |
| Scollie LLP | | 2023 |
| Scoona Ltd | Health & social care | 2009 |
| Scoop Drinks Limited | Professional & scientific | 2020 |
| Scopefully Limited | Information & communication | 2024 |
| Scorugger Limited | Wholesale & retail | 2022 |
| Scotch Mist Films Limited | Information & communication | 2008 |
| Scott Physiology Services Limited | Health & social care | 2019 |
| Scott's Sofas and Curtains Ltd | Manufacturing | 2023 |
| Scratch Concerts Limited | Professional & scientific | 1992 |
| Screencomms Ltd | Information & communication | 2011 |
| Script Intellectual Property LLP | | 2023 |
| Script IP Limited | Professional & scientific | 2012 |
| Scrum Professional Solutions Limited | Professional & scientific | 2009 |
| Scuffs (UK) Limited | Wholesale & retail | 2010 |
| Sculpted Earth Ltd | Professional & scientific | 2012 |
| Scutoid Limited | Professional & scientific | 2023 |