| One Little Beach Limited | Real estate | 2013 |
| One One Units Ltd | Real estate | 2021 |
| One South Molton CIC | Health & social care | 2025 |
| Online Business Services Ltd | Administrative & support | 2019 |
| Ookevin Technical and Educational Services Limited | Information & communication | 2013 |
| Open Gym East London Limited | Arts & recreation | 2023 |
| Opfikon Limited | Professional & scientific | 2011 |
| Optimum Heating Limited | Administrative & support | 1998 |
| Oramus & Clay Limited | Wholesale & retail | 2020 |
| Orangutan Graphics Limited | Information & communication | 2016 |
| Orchard Strategy Ltd | Professional & scientific | 2025 |
| Ordinary Living Cornwall Limited | Health & social care | 2025 |
| Ordinary Living Limited | Health & social care | 2003 |
| Oriole Consulting Limited | Professional & scientific | 2018 |
| ORS Genesis Limited | Financial services | 2016 |
| ORS Genius Limited | Professional & scientific | 2022 |
| ORS Genus Limited | Financial services | 2022 |
| Oscar Clark Co Ltd | Other services | 2020 |
| Ostlers Cider Mill Limited | Manufacturing | 2004 |
| Outboard Motor LOC Limited | Manufacturing | 2001 |
| Outcasts Devon CIC | Wholesale & retail | 2022 |
| Outdoor Fitness Company N&J Limited | Health & social care | 2016 |
| Overcrest Limited | Information & communication | 2015 |
| Owlings Ltd | Real estate | 2026 |
| Owls Nest Construction Ltd | Manufacturing | 2026 |
| O’Soap Ltd | Manufacturing | 2020 |
| P & a (SWM) Holdings Limited | Financial services | 2024 |
| P Jewell & Sons Garden & Landscaping Ltd | Administrative & support | 2017 |
| P M Clarke Commercials 2013 Limited | Administrative & support | 2013 |
| P&D Taverns Ltd | Hospitality | 2026 |
| P. S. & D. Limited | Real estate | 2003 |
| P. Wigley Limited | Other services | 2003 |
| P.D. Electrical Services (SW) Limited | Construction | 2023 |
| P.R. Fabrication Limited | Manufacturing | 2003 |
| Packfords & Young Limited | Administrative & support | 2001 |
| PAD Electrical & Home Automation Limited | Construction | 2022 |
| Padfields Funeral Directors Limited | Other services | 2022 |
| Paignton Pier Company | Professional & scientific | 1981 |
| Paignton Pier Leisure Limited | Arts & recreation | 2020 |
| Pain Free Strength Ltd | Other services | 2026 |
| Pamplona Property Limited | Real estate | 2022 |
| Pandora Court Management Company Limited | Other services | 1999 |
| Panoptic Group Ltd | Professional & scientific | 2016 |
| Panorama (Woolacombe) Limited | Households | 2020 |
| Pantheon Hospitality Limited | Hospitality | 2016 |
| PAR Dining Ltd. | Hospitality | 2011 |
| Para Fit UK Limited | Arts & recreation | 2012 |
| Parcel Shop Limited | Wholesale & retail | 2014 |
| Parish Property Limited | Real estate | 2019 |
| Park Flats Management Company Limited | Households | 2000 |
| Park View (Braunton) Management Company Limited | Real estate | 2018 |
| Parkview (Barnstaple) Management Company Limited | Households | 2009 |
| Parracombe Plant Hire Ltd | Administrative & support | 2020 |
| Passmore & Passmore Ltd. | Professional & scientific | 2016 |
| Past Productions Education Ltd | Other services | 2022 |
| Pastures New Produce Ltd. | Agriculture & fishing | 2016 |
| PAT Williams (Holdings) Ltd | Financial services | 2021 |
| PAT Williams Limited | Wholesale & retail | 1992 |
| Pathfields Business Park Phase 4 Limited | Real estate | 2020 |
| Patientia Equipment Ltd | Manufacturing | 2023 |
| Patternsoft Ltd | Information & communication | 2006 |
| Paul Allen Consultancy Ltd | Professional & scientific | 2023 |
| Paul Ashby-Crane and Company Limited | Real estate | 1978 |
| Paul Capner Cleaning Limited | Administrative & support | 2025 |
| Paul Clayton Painter & Decorator Limited | Construction | 2002 |
| Paul Gammon Construction Limited | Construction | 2006 |
| Paul Gammon Limited | Financial services | 2014 |
| Paul Roberts Ltd | Administrative & support | 2016 |
| PC Management Co. Ltd | Households | 2021 |
| PCB (EOT) Limited | Financial services | 2024 |
| Pcbl Limited | Construction | 2003 |
| Peace Lily's Ltd | Other services | 2021 |
| Peace Town Projects Limited | Financial services | 2021 |
| Peach Lemonade Ltd | Information & communication | 2026 |
| Peak Online Limited | Information & communication | 2015 |
| Peak Online TRI CIC | Arts & recreation | 2024 |
| Pearce Construction (Barnstaple) Limited | Construction | 1946 |
| Pearce Homes Limited | Construction | 2013 |
| Pelham Management Limited | Construction | 2000 |
| Pelican Fish Restaurant Limited | Hospitality | 2010 |
| Pelling Rail Consultancy Services Ltd | Professional & scientific | 2018 |
| Penhill Devon Limited | Agriculture & fishing | 2019 |
| Peninsula Management SW Limited | Administrative & support | 2017 |
| Peninsula Palliative Care Ltd. | Health & social care | 2011 |
| Peninsula Seafoods Limited | Wholesale & retail | 1995 |
| Peninsula Services SW Ltd | Construction | 2021 |
| Penny Furseman Travel Ltd | Administrative & support | 2012 |
| Pennygillam Auto Centre Limited | Real estate | 2008 |
| Pensato Limited | Other services | 2022 |
| Peregrine Mears Architects Ltd | Professional & scientific | 2013 |
| Perfect Score Competitions Ltd | Arts & recreation | 2026 |
| Perfect Tans Limited | Arts & recreation | 2014 |
| Perlin Homes Ltd | Real estate | 2019 |
| Perrantide Management Company Ltd | Households | 2021 |
| Perrins Financial Planning Limited | Professional & scientific | 2000 |
| Pescadito Ltd | Administrative & support | 2017 |
| Pete Fountain Traffic Management Services Ltd | Transport & logistics | 2015 |
| Pewter Graphics Limited | Information & communication | 2016 |
| Peyton Lane Limited | Financial services | 2019 |
| Pfam Client Services Limited | Real estate | 2025 |