| DPA Engineering Services Ltd | Professional & scientific | 2018 |
| DPB UK Transport Ltd | Transport & logistics | 2020 |
| DPR (Yorkshire) Limited | Transport & logistics | 2010 |
| DR Comms Ltd | Information & communication | 2021 |
| DR Nabs Clinic Ltd | Health & social care | 2025 |
| DR S. Keini Limited | Administrative & support | 2003 |
| DR Silke Newman Ltd | Health & social care | 2023 |
| Dracula Market Ltd | Wholesale & retail | 2024 |
| Dragonfly Capital Ltd | Real estate | 2025 |
| Dragonmeet Ltd | Arts & recreation | 2014 |
| Dragos Nita Transport Limited | Transport & logistics | 2024 |
| Draoi Consulting Ltd. | Information & communication | 2020 |
| DRD Conversions Ltd | Manufacturing | 2022 |
| Dreaming Napoli Ltd | Hospitality | 2022 |
| Dreamscape Installations Ltd | Construction | 2023 |
| Drive 2 Learn Ltd | Education | 2023 |
| Drive 4 YOU Limited | Transport & logistics | 2025 |
| Drive-In-Designs Limited | Construction | 2010 |
| Drivedom Ltd | Education | 2024 |
| Driven Supply Chain Ltd | Transport & logistics | 2021 |
| Driver Duffy Limited | Transport & logistics | 2025 |
| Drivesmart (Yorkshire) Ltd | Education | 2026 |
| Drizzle Land Limited | Hospitality | 2025 |
| Drone Pilot Academy Limited | Other services | 2015 |
| Drop Dash UK Ltd | Wholesale & retail | 2023 |
| DRS Motor Company Ltd | Wholesale & retail | 1999 |
| DRT Heating Services Limited | Construction | 2003 |
| Drywall Construction Services Ltd | Construction | 2022 |
| DS Accounting Solutions Limited | Professional & scientific | 2023 |
| DS Complex Care Limited | Health & social care | 2022 |
| DS Consulting (2015) Co Ltd | Professional & scientific | 2015 |
| DS Conveyancing Services Limited | Other services | 2023 |
| DSH Finance Limited | Public administration | 2016 |
| Dshb Ventures Ltd | Construction | 2025 |
| DSI Services (Nerja) Limited | Households | 1986 |
| DSL Roofline Limited | Construction | 2025 |
| DSM Roofing Limited | Construction | 2000 |
| DSP Print and Design Limited | Manufacturing | 2022 |
| DSW Electrical Installations Limited | Construction | 2022 |
| DTA Developments Limited | Real estate | 2026 |
| DTO Plumbing & Heating Limited | Construction | 2022 |
| Dubitareala Ltd | Wholesale & retail | 2026 |
| Dueforward Limited | Households | 1987 |
| Duet Properties Limited | Real estate | 2001 |
| Dugr Limited | Arts & recreation | 2023 |
| Duncan Technical Services Limited | Health & social care | 2006 |
| Dundee Engineering Services Limited | Construction | 2008 |
| DUO Energy Limited | Construction | 2025 |
| Durkan Financial Planning Ltd | Financial services | 2023 |
| Dutchys Windows Barnsley & Rotherham Limited | Administrative & support | 2023 |
| Dutchyton&Co Ltd | Wholesale & retail | 2025 |
| Dutton HGV Services Ltd | Transport & logistics | 2018 |
| Dutton Phillips Limited | Construction | 2003 |
| Dutz Ltd | Transport & logistics | 2018 |
| DVL Logistics Limited | Transport & logistics | 2024 |
| DVS Estates Ltd | Real estate | 2020 |
| DW Accountants Limited | Professional & scientific | 2025 |
| DW Plumbing & Heating (Yorkshire) Limited | Construction | 2023 |
| DW3 Products Group Limited | Professional & scientific | 2014 |
| DW3 Products Holdings Limited | Professional & scientific | 2014 |
| Dwds Limited | Transport & logistics | 2006 |
| Dwilson Ltd | Hospitality | 2024 |
| Dybb Healthcare Limited | Health & social care | 2021 |
| DYG Ltd | Information & communication | 2018 |
| Dynamic CHP Limited | Professional & scientific | 2019 |
| Dynamic Health and Performance Ltd | Extraterritorial | 2025 |
| Dynamic Mechanical Services Ltd | Professional & scientific | 2016 |
| Dynamic Recovery Ltd | Transport & logistics | 2018 |
| Dynamic Recycling Ltd | Water & waste | 2018 |
| Dynamo Equestrian Limited | Hospitality | 2024 |
| Dyson Investments Limited | Real estate | 2024 |
| Dyson Property Investments Limited | Real estate | 2019 |
| Dyva Limited | Transport & logistics | 2019 |
| D’Favoured Ltd | Health & social care | 2026 |
| E & a Leech Limited | Wholesale & retail | 1975 |
| E & C Travel Ltd | Transport & logistics | 2026 |
| E & L Roofing Specialists Limited | Construction | 2025 |
| E & M Sushi Ltd | Wholesale & retail | 2024 |
| E & P Projects & Consultancy Limited | Professional & scientific | 2021 |
| E a Fielding Limited | Professional & scientific | 2022 |
| E J Lidster (Barnsley) Limited | Construction | 2014 |
| E J Lidster (Construction) Burton Park Limited | Construction | 1996 |
| E J Lidster (Sales) Ltd | Construction | 2013 |
| E R Fire Protection Services Limited | Professional & scientific | 2003 |
| E Squared Coffee Corner Ltd | Hospitality | 2026 |
| E&A Bodywork Limited | Health & social care | 2017 |
| E&D Property Ltd | Real estate | 2023 |
| E&H Investment Group Limited | Real estate | 2025 |
| E&L Logistics Ltd | Transport & logistics | 2024 |
| E-T-E Solutions Ltd | Professional & scientific | 2022 |
| E.Jennings & Co Limited | Wholesale & retail | 2001 |
| E.L. Mount & Co. Limited | Agriculture & fishing | 1963 |
| E.S Collective Limited | Professional & scientific | 2024 |
| E.S.P Laser Holdings Limited | Financial services | 2023 |
| E.S.P. Laser Cutting Limited | Manufacturing | 1994 |
| E3 Business Incubator Limited | Information & communication | 2014 |
| Each Limited | Hospitality | 2014 |
| EAD Holdings Limited | Financial services | 2019 |
| Eaden's Bar 2 Limited | Hospitality | 2025 |
| Eaden’S Bar Ltd | Hospitality | 2022 |