| Dean Andrew Haigh Limited | Transport & logistics | 2015 |
| Dean Forward Motorsport Limited | Manufacturing | 2010 |
| Dean Hamshaw Ltd | Extraterritorial | 2022 |
| Deane Dwellings Ltd | Real estate | 2019 |
| Dearne Street 1964 Limited | Extraterritorial | 2013 |
| Dearne Valley Carboot Limited | Real estate | 2020 |
| Dearne Valley Financial Services Limited | Financial services | 2024 |
| Dearne Valley Pet Centre Ltd | Wholesale & retail | 2018 |
| Dearne Valley Scaffolding Limited | Construction | 2022 |
| Deborah Robbins Ltd | Administrative & support | 2014 |
| Debukol Ltd | Wholesale & retail | 2025 |
| Decimals Count Ltd | Extraterritorial | 2011 |
| Decoeffect Limited | Construction | 2018 |
| Decorative Screens Limited | Extraterritorial | 2019 |
| Decorative Spray Solutions Limited | Construction | 2023 |
| Dedeone Ltd | Transport & logistics | 2023 |
| Deejay Groundworks Ltd | Construction | 2020 |
| Deepblue Global Limited | Administrative & support | 2021 |
| Deepcar Motor Homes International Limited | Wholesale & retail | 1999 |
| Defender Security Services Ltd | Administrative & support | 2011 |
| Dejoch Limited | Transport & logistics | 2019 |
| Del-A-Court Limited | Construction | 1998 |
| Deli 95 Limited | Hospitality | 2019 |
| Deli City Limited | Extraterritorial | 2008 |
| Delicate Care Staffing Ltd | Other services | 2023 |
| Delicii Mini Market Ltd | Wholesale & retail | 2022 |
| Delicious Media Limited | Information & communication | 2011 |
| Delish Shop Ltd | Wholesale & retail | 2018 |
| Delitalia Limited | Hospitality | 2004 |
| Deliveruk Logistics Ltd | Transport & logistics | 2020 |
| Delivery on Ltd | Transport & logistics | 2024 |
| Della Pizza Foods Limited | Hospitality | 2020 |
| Delta Adhesives Limited | Wholesale & retail | 1991 |
| Delta Redwood Developments Limited | Financial services | 2022 |
| Delta Rooftop Solutions Ltd | Construction | 2017 |
| Delta Xray Limited | Health & social care | 2025 |
| Delyrom Ltd | Hospitality | 2026 |
| DEM Holdings Barnsley Ltd | Financial services | 2024 |
| DEM Window Solutions Limited | Manufacturing | 2000 |
| Demand Fabrications Limited | Manufacturing | 2010 |
| Demina Clothing Limited | Manufacturing | 2015 |
| Dempsey and Sons Limited | Real estate | 2018 |
| Dena Enviro Build Ltd | Manufacturing | 2012 |
| Dena Nano-Wood Ltd | Manufacturing | 2012 |
| Dena Nanotech Ltd | Manufacturing | 2007 |
| Denbank Property Company Limited | Real estate | 2000 |
| Denby Dale Shirt Co. (Holdings) Limited | Professional & scientific | 2015 |
| Denby Dale Shirt Co., Limited | Manufacturing | 1965 |
| Deniro's Pizza Limited | Hospitality | 1999 |
| Denis Bray's Limited | Administrative & support | 2009 |
| Denjaemsfry Limited | Wholesale & retail | 2025 |
| Dennis Higgs Transport Limited | Wholesale & retail | 1999 |
| Dent Art PDR Limited | Wholesale & retail | 2017 |
| Dent Dynamics UK Ltd | Wholesale & retail | 2018 |
| Dentwizard (Yorkshire) Ltd | Wholesale & retail | 2022 |
| Derbyshire Insulation Ltd | Construction | 2024 |
| Derbyshire Property Holdings Ltd | Construction | 2019 |
| DES Vignes Care Incorporative Ltd | Health & social care | 2019 |
| Desene Ltd | Other services | 2023 |
| Design in Wood Limited | Manufacturing | 2019 |
| Designer Floors UK Limited | Construction | 2023 |
| Designer Supply Ltd | Wholesale & retail | 2025 |
| Desire 1 Limited | Hospitality | 2022 |
| Dessert Krush (Barnsley) Ltd | Hospitality | 2024 |
| Desserts Stone Ltd | Hospitality | 2025 |
| Detect and Protect Security Services Ltd | Administrative & support | 2026 |
| DEV AI Limited | Information & communication | 2024 |
| Developments by Boutique (EL) Ltd | Construction | 2024 |
| Developments by Boutique (Elsecar) Ltd | Construction | 2025 |
| Developments by Boutique (Gleadless) Ltd | Construction | 2025 |
| Developments by Boutique (Heysham Green ) Limited | Construction | 2019 |
| Developments by Boutique (Jump) Ltd | Construction | 2025 |
| Developments by Boutique (Wortley Road) Ltd | Construction | 2025 |
| Developments by Boutique Limited | Construction | 2012 |
| Developments by Boutique Yorkshire Ltd | Construction | 2022 |
| Dewies Limited | Wholesale & retail | 2021 |
| Dexters Treats Limited | Hospitality | 2025 |
| Deydrop Ltd | Administrative & support | 2024 |
| DF Livingston Ltd | Wholesale & retail | 2019 |
| DF Refrigeration Limited | Manufacturing | 2022 |
| DF Surveys Limited | Professional & scientific | 2025 |
| Dfgb Trading Ltd | Administrative & support | 2013 |
| DFR Home Improvements Ltd | Construction | 2025 |
| Dgcom Limited | Wholesale & retail | 2023 |
| DH Tyres Limited | Manufacturing | 2026 |
| Dhaliwal Convenience Store Ltd | Wholesale & retail | 2026 |
| Dhkb Limited | Administrative & support | 2007 |
| Dhmarrion Holdings Limited | Financial services | 2024 |
| DHS Trade Solutions Ltd | Wholesale & retail | 2025 |
| DIA Consulting Limited | Health & social care | 2014 |
| Diablo Groundworks & Civils Ltd | Construction | 2021 |
| Diadem GRP Limited | Manufacturing | 2018 |
| Dial Barnsley | Health & social care | 2004 |
| Diamond Boilers Limited | Construction | 2019 |
| Diamond Civils and Groundworks Ltd | Professional & scientific | 2017 |
| Diamond Restorations Ltd | Manufacturing | 2024 |
| Diamond Triangle Ltd | Wholesale & retail | 2020 |
| Dibsa Structures Limited | Manufacturing | 1991 |
| Dickinson Properties, Yorkshire Ltd | Real estate | 2022 |
| Dickinson Truck & BUS Ltd | Wholesale & retail | 2016 |