| Emery House Management Company Ltd | Households | 2010 |
| Emex Pro Ltd | Real estate | 2022 |
| EMF Limited | Information & communication | 2008 |
| EMI Construct Ltd | Construction | 2026 |
| Emihar Limited | Real estate | 2017 |
| Emily James Investments Limited | Real estate | 2015 |
| Emma Dashwood Psychotherapy Ltd | Health & social care | 2025 |
| Emma Howe Interior Design Ltd | Professional & scientific | 2025 |
| Emmanuel Childcare Services Ltd | Health & social care | 2020 |
| Emmanuel Electricals Ltd | Construction | 2012 |
| Emmanuel Estates JAN 26 SPV01 Ltd | Real estate | 2026 |
| Emmanuel Estates Limited | Real estate | 2021 |
| Emmarachelconsulting Ltd | Other services | 2022 |
| Emmed Ltd | Wholesale & retail | 2025 |
| Emmeli Kimhi Ltd | Extraterritorial | 2021 |
| Empire Trading & Commerce Ltd | Wholesale & retail | 2021 |
| Employability Limited | Administrative & support | 2006 |
| Empowered Mothers Network CIC | Education | 2026 |
| Empyrean 355 Ltd | Real estate | 2011 |
| EMS Force Ltd | Hospitality | 2021 |
| EMX Dynamics Ltd | Manufacturing | 2009 |
| EN5 Cafe Ltd | Hospitality | 2024 |
| EN5RADIO Limited | Information & communication | 2021 |
| Enade Limited | Construction | 2020 |
| Encanta Talent Management Ltd | Arts & recreation | 2018 |
| Enchante Yasemin Ltd | Other services | 2023 |
| Encore Plumbing & Heating Limited | Professional & scientific | 2015 |
| END of Play Productions Ltd | Information & communication | 2011 |
| END to END Business and Finance Solutions Ltd | Professional & scientific | 2021 |
| Endeavour Meats UK Limited | Wholesale & retail | 2025 |
| Endicott Consultancy Ltd | Professional & scientific | 2024 |
| Endo Gazani Ltd | Health & social care | 2022 |
| Endoclinic Limited | Professional & scientific | 2010 |
| Eneji Ltd | Other services | 2026 |
| Energy & Telecom Solutions Ltd | Administrative & support | 2013 |
| Energy Enhancement Centre Ltd | Arts & recreation | 2023 |
| Energy for London Ltd | Professional & scientific | 2012 |
| Energy Power Solution Ltd | Wholesale & retail | 2011 |
| Energy Unplugged Limited | Professional & scientific | 2017 |
| Enfes Express Ltd | Hospitality | 2026 |
| Enfield Catering Limited | Hospitality | 2016 |
| Engage Financial Services Ltd | Financial services | 2017 |
| Engagewell Care Limited | Health & social care | 2023 |
| Engelec Ltd | Construction | 2022 |
| Engleflex Ltd | Wholesale & retail | 2025 |
| Enhance Sport & Health Limited | Professional & scientific | 2013 |
| ENI Jewellery Ltd | Wholesale & retail | 2016 |
| Enjo Limited | Wholesale & retail | 2003 |
| Enlighten Psychology Services Ltd | Education | 2025 |
| Ennerdale Court Holding Limited | Real estate | 2024 |
| Ensign Advanced Software Ltd | Information & communication | 2026 |
| Ensign Advanced Solutions Ltd | Information & communication | 2026 |
| Ensign Advanced Systems Limited | Information & communication | 1989 |
| Entertainment Kids Ltd | Manufacturing | 2026 |
| Entertainment Production Ltd | Information & communication | 2019 |
| Entire Office Ltd | Wholesale & retail | 2012 |
| Entrees International Limited | Wholesale & retail | 1997 |
| Entrust Properties Ltd | Hospitality | 2023 |
| Enviro (London) Ltd | Water & waste | 2022 |
| ENZO367 Ltd | Wholesale & retail | 2024 |
| Eocene Property Developments Limited | Extraterritorial | 2016 |
| EOS Corporate Investments Limited | Wholesale & retail | 2023 |
| EOS Fleet Solutions Ltd | Administrative & support | 2017 |
| EP Kebab Ltd | Hospitality | 2025 |
| Epayerz Technology Ltd | Information & communication | 2020 |
| EPC Expert Limited | Information & communication | 2007 |
| EPH Wealth Management Ltd | Professional & scientific | 2015 |
| Ephesus Catering Limited | Hospitality | 2018 |
| Epoch Property Developments Limited | Extraterritorial | 2016 |
| Eponymous Limited | Administrative & support | 2004 |
| Epping Grange Management Company Limited | Households | 2001 |
| Epping Tandoori Ltd | Administrative & support | 2024 |
| Equalnew Property Management Limited | Households | 1993 |
| Equibid Ltd | Administrative & support | 2019 |
| Equine Rehabilitation Limited | Agriculture & fishing | 2021 |
| Equitas Capital Limited | Financial services | 2020 |
| Equitas Capital NO 1 Limited | Financial services | 2024 |
| Equitas Capital NO 2 Limited | Financial services | 2026 |
| Equitem Limited | Hospitality | 2011 |
| Erganian Limited | Real estate | 2019 |
| ERP Data Systems Limited | Information & communication | 2021 |
| Erving Limited | Administrative & support | 2018 |
| Erwin Dull Limited | Information & communication | 2014 |
| ES Bulut Ltd | Real estate | 2024 |
| ES Coaches Limited | Transport & logistics | 2019 |
| ES Faraday Ltd | Administrative & support | 2017 |
| Esel Fashion and Textile Ltd | Wholesale & retail | 2020 |
| Esenem Limited | Real estate | 2023 |
| Esentials Limited | Other services | 2006 |
| ESG Workplace Solutions Ltd | Transport & logistics | 2026 |
| ESH Property Advisors Ltd | Professional & scientific | 2014 |
| Esha Consultancy Ltd | Information & communication | 2013 |
| Esolate Ltd | Construction | 2019 |
| ESP Investment Group Ltd | Real estate | 2021 |
| Esrg Consulting Ltd | Other services | 2014 |
| Essential Juices Ltd | Manufacturing | 2019 |
| Essential Mortgage & Money Solutions Limited | Financial services | 2005 |
| Essential Technology Limited | Professional & scientific | 1999 |
| Essex Car Park Holdings Ltd | Transport & logistics | 2020 |
| Essex Pathology (Services) Ltd. | Health & social care | 2012 |