| DRD Property & Garden Maintenance Limited | Construction | 2017 |
| Dream Music Ltd | Information & communication | 2025 |
| Dream RF Ltd | Professional & scientific | 2024 |
| Dream Xata Limited | Real estate | 2023 |
| Dreamhomz Ltd. | Real estate | 2016 |
| Dreaming in Colour Films Ltd | Information & communication | 2019 |
| Dreams Construction Group Ltd | Construction | 2022 |
| Dreytons Group Ltd | Financial services | 2024 |
| Dreytons Haven Care Ltd | Health & social care | 2026 |
| Dreytons Homes Ltd | Real estate | 2024 |
| Dreytons Housing Limited | Real estate | 2019 |
| Dreytons Supported Housing CIC | Real estate | 2026 |
| Dreytons TLC Limited | Health & social care | 2024 |
| Drinkstill Ltd | Wholesale & retail | 2026 |
| Driven Media Ltd | Other services | 2025 |
| Driver US Ltd | Transport & logistics | 2022 |
| Drivex LDN Ltd | Administrative & support | 2026 |
| Drizzle Bakehouse Limited | Wholesale & retail | 2023 |
| DRN Finance Limited | Administrative & support | 2017 |
| DRN Group Limited | Administrative & support | 2017 |
| Droe Holdings LLP | | 2020 |
| Droplet Health Limited | Extraterritorial | 2019 |
| Drumhut Limited | Information & communication | 2013 |
| Drummodyne Consulting Limited | Professional & scientific | 2011 |
| Drummond Bell Limited | Administrative & support | 2018 |
| DRUNCHSW3 Limited | Hospitality | 2015 |
| Drvz Ltd | Real estate | 2017 |
| Dryklad Rainscreen Systems Ltd | Construction | 2020 |
| Drymonsoon Limited | Wholesale & retail | 2013 |
| DS Inspired Ltd | Financial services | 2021 |
| DS Physiotherapy Limited | Health & social care | 2013 |
| DS Property Invest Limited | Real estate | 2018 |
| DS Sign Installations Ltd | Other services | 2016 |
| DS Wines Ltd | Wholesale & retail | 2024 |
| DSA Dawn Ltd | Health & social care | 2013 |
| Dsktop Limited | Wholesale & retail | 2024 |
| Dsmuk Consulting Ltd | Mining & quarrying | 2022 |
| Dsse UK Ltd | Wholesale & retail | 2024 |
| DSV Logistics Ltd | Transport & logistics | 2026 |
| DSZ Drive Limited | Administrative & support | 2025 |
| DT Spark Ltd | Construction | 2024 |
| DTA Property LLP | | 2021 |
| Dtmpm Ltd | Professional & scientific | 2024 |
| DTS Construction & Fitting Limited | Construction | 2009 |
| DU Flooring Ltd | Construction | 2025 |
| Dual Box Properties Ltd | Administrative & support | 2025 |
| Duchess Street Investments Ltd | Administrative & support | 2014 |
| Duchy Media Ltd. | Wholesale & retail | 2013 |
| Dudman Media Ltd | Information & communication | 2012 |
| Dullbar Limited | Information & communication | 2014 |
| Duluth Limited | Professional & scientific | 1977 |
| Dunbar Property Limited | Real estate | 2020 |
| Dunbay 2003 Limited | Households | 2003 |
| Duncan Phillips Management Limited | Real estate | 2020 |
| Dundene Associates Limited | Professional & scientific | 1997 |
| Dune Edge Consultancy Ltd | Professional & scientific | 2023 |
| Dune Edge Investments Ltd | Real estate | 2023 |
| Dunn Right Limited | Construction | 2017 |
| Dunoon Capital Ltd | Real estate | 2017 |
| Duplex Care Ltd | Construction | 2016 |
| Duplex Group Ltd | Real estate | 2020 |
| Durian Lending Limited | Real estate | 2022 |
| Durian Property Limited | Real estate | 2025 |
| Durway Ltd | Hospitality | 2018 |
| DVT London Ltd | Hospitality | 2025 |
| Dwfittings Ltd | Construction | 2021 |
| DY Holdings Ltd | Financial services | 2025 |
| Dyamore Limited | Real estate | 2018 |
| Dyanko Ltd | Construction | 2025 |
| Dydm Ltd | Real estate | 2020 |
| Dylan Administration Services Limited | Public administration | 2012 |
| Dynamic Recruitment Services Ltd | Administrative & support | 2020 |
| Dynamic Talent Group Ltd | Information & communication | 2021 |
| Dynamiclynx Limited | Information & communication | 2013 |
| Dyno London Ltd | Professional & scientific | 2025 |
| Dyno UK Ltd | Professional & scientific | 2020 |
| Dyrham Park Country Club Limited | Arts & recreation | 1963 |
| DZG Consulting Limited | Professional & scientific | 2015 |
| Dzhevo Ltd | Construction | 2026 |
| Dēpart Education Ltd | Education | 2025 |
| E & N Food Products Limited | Manufacturing | 2003 |
| E Flynn Demolition and Construction Ltd | Construction | 2016 |
| E M Steer Investments Ltd | Financial services | 2019 |
| E Riley Associates Limited | Professional & scientific | 2009 |
| E Vaughan Limited | Construction | 1997 |
| E&B Quality Construction Ltd | Construction | 2025 |
| E&L Estates Ltd | Real estate | 2019 |
| E-Progress Ltd | Information & communication | 2013 |
| E.C.Edwards Limited | Construction | 1963 |
| E.T.T. Electrical Services Limited | Construction | 2014 |
| E360 LLP | | 2001 |
| EA Management Consultants Limited | Real estate | 2012 |
| EA Real Estate Holdings Ltd | Real estate | 2023 |
| Eager Management Ltd | Professional & scientific | 2026 |
| Eager Productions Limited | Information & communication | 2015 |
| Eagle Development Properties Ltd | Real estate | 2019 |
| Eagle Efforts Ltd | Information & communication | 2022 |
| Eagle Insights Ltd. | Information & communication | 2017 |
| Eagle Investment Bridging Company Limited | Financial services | 2024 |
| Eagle Parking Ltd | Transport & logistics | 2018 |