| David Construction Services Ltd | Construction | 2012 |
| David Gordon Ortho Limited | Health & social care | 2013 |
| David Jones OD Ltd | Professional & scientific | 2025 |
| David Maycox & Co Limited | Professional & scientific | 2012 |
| David Maycox Holdings Limited | Financial services | 2018 |
| Dawn Business Solutions Ltd | Professional & scientific | 2008 |
| Dawn Digitals Ltd | Professional & scientific | 2022 |
| Dawson Hair Ltd | Other services | 2018 |
| Daxan Limited | Administrative & support | 2000 |
| Day 1 Express Ltd | Wholesale & retail | 2012 |
| Day of the RAJ Express Limited | Hospitality | 2017 |
| Day of the RAJ Limited | Hospitality | 1996 |
| Dayanik Limited | Health & social care | 2025 |
| Daycare Health & Wellness Centre Ltd | Public administration | 2019 |
| Dayco Artificial Grass Limited | Wholesale & retail | 2012 |
| Dayco Cleaning Ltd | Administrative & support | 2025 |
| Dayco Group Limited | Professional & scientific | 2025 |
| Dayco Property Maintenance Ltd | Construction | 2009 |
| Daydream Homes (Hampshire) Limited | Construction | 2022 |
| Dazzle & Dance CIC | Education | 2021 |
| DB Courier Swindon Ltd | Transport & logistics | 2018 |
| DB Seret Technologies Limited | Wholesale & retail | 2024 |
| DBC Stores Ltd | Real estate | 2019 |
| DBI Group Limited | Financial services | 2021 |
| DBK Maintenance 25 Ltd | Other services | 2025 |
| DBK Maintenance Limited | Other services | 2023 |
| Dbmp Ltd | Construction | 2013 |
| Dbno Clothing Limited | Administrative & support | 2014 |
| DC Facility Management Ltd | Administrative & support | 2017 |
| DC Group Research Limited | Construction | 2023 |
| DCB FUN & Fitness Limited Limited | Education | 2019 |
| Dccl Ltd | Information & communication | 2023 |
| Dccw.E Retail Ltd | Financial services | 2020 |
| DCH Marketing Services Limited | Administrative & support | 2002 |
| DCM US Multi-Family Homes PLC | Financial services | 2020 |
| Dctaxagent Ltd | Professional & scientific | 2020 |
| Dcwm Ltd | Administrative & support | 2024 |
| Ddddd Ltd | Real estate | 2018 |
| DDS Cardio Ltd | Health & social care | 2023 |
| DE Campi Fine Interiors Limited | Construction | 2012 |
| DE Cave Nominees Limited | Extraterritorial | 1999 |
| DE Chirico Limited | Real estate | 2021 |
| DE Reyher Quintarelli | Health & social care | 2006 |
| DE Savary London Ltd | Wholesale & retail | 2016 |
| DE Silvo Limited | Wholesale & retail | 2007 |
| DE Vere Letting Bureau Limited | Real estate | 2000 |
| DE Wine Company Limited | Other services | 2022 |
| Deal Investment Properties Ltd | Real estate | 2020 |
| Deallo Limited | Real estate | 2021 |
| Deallo VAT Ltd | Real estate | 2022 |
| Dean Point Ltd | Financial services | 2021 |
| Deane Wakefield Limited | Administrative & support | 2011 |
| Deans Point Ltd | Financial services | 2023 |
| Debaere Kiosk Limited | Manufacturing | 2019 |
| Debbie Rimmer Management Limited | Information & communication | 2014 |
| Debeauvoir Properties Limited | Real estate | 2017 |
| Debson & Co Limited | Professional & scientific | 2020 |
| Debson Consultants Limited | Extraterritorial | 1993 |
| Decode X Consulting Limited | Professional & scientific | 2020 |
| Decorait Limited | Administrative & support | 2020 |
| Dedicated Art Ltd | Wholesale & retail | 2018 |
| DEE DEE Thai Food Limited | Hospitality | 2020 |
| Deeley Limited | Construction | 2004 |
| Deep Agency UK Limited | Manufacturing | 2020 |
| Deep Ocean Business Translation Co. Ltd. | Professional & scientific | 2012 |
| Deep Orange Limited | Professional & scientific | 2016 |
| Deep Serv Ltd | Construction | 2022 |
| Deer Software Services Ltd | Information & communication | 2024 |
| Deezed Limited | Real estate | 2016 |
| DEF Electrical Limited | Professional & scientific | 2021 |
| DEF GAS & Electrical Limited | Professional & scientific | 2023 |
| DEF Heating and Plumbing Ltd | Professional & scientific | 2018 |
| DEF Heating Limited | Professional & scientific | 2019 |
| DEF Plumbing and Heating Ltd | Professional & scientific | 2018 |
| Definition Music Limited | Arts & recreation | 2009 |
| Defne & Ecem Ltd | Hospitality | 2025 |
| Deft Limited | Agriculture & fishing | 2023 |
| Deinonychus Ltd | Arts & recreation | 2009 |
| Deja BRU Limited | Manufacturing | 2022 |
| DEL Carajo Limited | Professional & scientific | 2004 |
| Dele Marketing Limited | Information & communication | 2020 |
| Delhivery UK Limited | Transport & logistics | 2026 |
| Delia Design Limited | Manufacturing | 2018 |
| DELIVERY4U Limited | Transport & logistics | 2020 |
| Delta Construction (London) Limited | Construction | 2024 |
| Delta Developments (Alton) Limited | Real estate | 2001 |
| Delta Developments Limited | Real estate | 1958 |
| Delta Sigma Algorithms Limited | Information & communication | 2023 |
| Deltaristo Consulting Ltd | Professional & scientific | 2011 |
| Deluxe Dermis Ltd | Other services | 2023 |
| DEM Market Ltd | Wholesale & retail | 2020 |
| Demeter Aviation Limited | Administrative & support | 2020 |
| Demeter Estate Ltd | Real estate | 2021 |
| Demetriou Properties Ltd | Real estate | 2000 |
| Dempster Projects Limited | Real estate | 2023 |
| DEN & Co. Limited | Other services | 1995 |
| DEN Kara Communications Ltd | Professional & scientific | 2019 |
| DEN Physio Ltd | Health & social care | 2023 |
| Denava Limited | Financial services | 2020 |
| Denbrook Limited | Real estate | 2003 |