| Skills First Ltd | Professional & scientific | 2020 |
| Skillscope (Global) Ltd | Information & communication | 2020 |
| Skinfusion Clinic Limited | Health & social care | 2016 |
| Skinova Beauty and Wellness Ltd | Wholesale & retail | 2025 |
| SKM Works Ltd | Wholesale & retail | 2025 |
| Skmak Ltd | Arts & recreation | 2024 |
| Skmei Tech Ltd | Wholesale & retail | 2018 |
| SKN Consulting Ltd | Information & communication | 2018 |
| SKN IT Limited | Information & communication | 2026 |
| SKOOL21 Limited | Education | 2023 |
| Skrritservice Limited | Information & communication | 2026 |
| Skulter Ltd | Wholesale & retail | 2025 |
| Skuza Investments Ltd | Real estate | 2025 |
| Sky Global Impex Ltd | Wholesale & retail | 2026 |
| Sky High Installation UK Ltd | Manufacturing | 2013 |
| Sky High Property Investment Ltd | Real estate | 2017 |
| Sky MOB Construct Ltd | Construction | 2025 |
| Sky Plus Ltd | Hospitality | 2025 |
| Sky Sea Info Ltd | Manufacturing | 2021 |
| Sky Security and Services Ltd | Administrative & support | 2025 |
| Sky Touch Architecture Ltd | Construction | 2025 |
| Skyakimov Limited | Construction | 2024 |
| Skybridge Finance Limited | Wholesale & retail | 2025 |
| Skyline Market Ltd | Wholesale & retail | 2024 |
| Skyline Solar Control Limited | Wholesale & retail | 2004 |
| Skypak Services Ltd | Transport & logistics | 2025 |
| Skype Limited | Wholesale & retail | 2026 |
| Skypoint Services Ltd | Real estate | 2020 |
| Skysharp Security Services Limited | Administrative & support | 2006 |
| Skywilly Ltd | Construction | 2022 |
| Slavannahome Rentals Ltd | Real estate | 2025 |
| Slimline Contractors Limited | Other services | 2018 |
| Slsjk Ltd | Wholesale & retail | 2025 |
| SLV Premium Transport Ltd | Transport & logistics | 2024 |
| SM Build&Design Limited | Construction | 2026 |
| SM Foods Limited | Wholesale & retail | 2020 |
| SM Optometry Limited | Health & social care | 2022 |
| SM Realty Ltd | Real estate | 2025 |
| SM Shopfronts Ltd | Manufacturing | 2015 |
| Smaan Ltd | Wholesale & retail | 2021 |
| Small Business Growth Consulting Limited | Hospitality | 2018 |
| Small London Fashion House Limited | Wholesale & retail | 2022 |
| Smallworld Onlne Services Ltd | Professional & scientific | 2013 |
| Smart Alliance Security Services Limited | Administrative & support | 2015 |
| Smart Buyer Wholesale Limited | Wholesale & retail | 2013 |
| Smart Construct Ltd | Manufacturing | 2020 |
| Smart Development London Ltd | Professional & scientific | 2020 |
| Smart Gadgets 4U Ltd | Wholesale & retail | 2016 |
| Smart Gift Limited | Wholesale & retail | 2016 |
| Smart Homes Investment Ltd | Real estate | 2021 |
| Smart Invest Associates Ltd | Real estate | 2017 |
| Smart Learning Solution Limited | Education | 2023 |
| Smart NET IT Solutions Ltd | Administrative & support | 2013 |
| Smart Partners Ltd | Professional & scientific | 2015 |
| Smart Print and Display Ltd | Arts & recreation | 2017 |
| Smart Reach Services Ltd | Administrative & support | 2026 |
| Smart Roundabout Limited | Information & communication | 2023 |
| Smart School Limited | Education | 2022 |
| Smart TAB Hire Ltd | Wholesale & retail | 2019 |
| Smart Tax Solutions Ltd | Professional & scientific | 2018 |
| Smartcleanse & Co Ltd | Administrative & support | 2025 |
| Smartex Sourcing & Supply Ltd | Manufacturing | 2020 |
| Smep Consultancy Services Ltd | Professional & scientific | 2017 |
| Smexpress Ltd | Wholesale & retail | 2019 |
| Smile Olans Ltd | Construction | 2022 |
| Smiles Caterers Ltd | Other services | 2020 |
| Smiles Everyday Ltd | Wholesale & retail | 2025 |
| SMJ Property Development Ltd | Real estate | 2023 |
| SMK Protective Helath Limited | Wholesale & retail | 2026 |
| SMM Systems Ltd | Information & communication | 2026 |
| SMN Management Consultants Limited | Professional & scientific | 2019 |
| Smokditout Limited | Hospitality | 2025 |
| Smooth Work Builders Ltd | Construction | 2025 |
| Smoothers Ltd | Wholesale & retail | 2024 |
| SMR Construct Ltd Ltd | Construction | 2025 |
| SMS Care Solution Limited | Health & social care | 2020 |
| SMS Mode UK Ltd | Wholesale & retail | 2025 |
| Smurf Tech Hub Ltd | Construction | 2024 |
| SN Global Recruitment Limited | Administrative & support | 2023 |
| SN Paradise UK Ltd | Real estate | 2019 |
| SN Property Services Limited | Real estate | 2022 |
| SN Traders (UK) Ltd | Hospitality | 2013 |
| Snappy Commercial Holdings Ltd | Real estate | 2025 |
| Snappy Freight Services Ltd | Transport & logistics | 2024 |
| Snappy Open Storage Ltd | Real estate | 2026 |
| Snappy Self Storage Croydon Ltd | Transport & logistics | 2024 |
| Snappy Self Storage Knockholt Ltd | Real estate | 2025 |
| Snappy Self Storage Ltd | Transport & logistics | 2023 |
| Snappy Storage Solutions Ltd | Real estate | 2024 |
| Snapshot Selfiebooth Ltd | Hospitality | 2024 |
| Sndautoworks Ltd | Wholesale & retail | 2025 |
| SNH Designs Ltd | Professional & scientific | 2021 |
| SNM Digital Ltd | Professional & scientific | 2022 |
| SNS Investment Properties Limited | Real estate | 2021 |
| Snsr Ltd | Transport & logistics | 2015 |
| Snsr Products Ltd | Wholesale & retail | 2026 |
| SO Railway Ltd | Construction | 2019 |
| Social Issues Limited | Information & communication | 2019 |
| Soda Burst UK Limited | Other services | 2008 |
| Sofex Furniture Limited | Administrative & support | 2017 |