| Rowlands London Garage Limited | Wholesale & retail | 2022 |
| Rowlinson Sharp Limited | Wholesale & retail | 2023 |
| Roytandoori Ltd | Hospitality | 2024 |
| RR MON Construction Ltd | Construction | 2015 |
| Rrzz Holding Limited | Real estate | 2022 |
| RSB Properties (NW) Limited | Real estate | 2009 |
| Rubisco Limited | Extraterritorial | 2020 |
| Ruby KIN Bangor Ltd | Hospitality | 2023 |
| Ruby KIN Restaurant Ltd | Hospitality | 2025 |
| Ryan James Limited | Wholesale & retail | 2003 |
| S & J Gibbons Enterprises Ltd | Real estate | 2013 |
| S & L Cottages Limited | Real estate | 2022 |
| S & V Trading Cards Limited | Wholesale & retail | 2026 |
| S and H Hospitality Ltd | Hospitality | 2026 |
| S and L Logistics Limited | Administrative & support | 2025 |
| S G Gray Amusements Limited | Arts & recreation | 2025 |
| S Joinery Limited | Manufacturing | 2023 |
| S Mccabe & Sons Holdings Ltd | Financial services | 2023 |
| S Mccabe & Sons Properties Ltd | Real estate | 2023 |
| S Owen Holdings Ltd | Financial services | 2026 |
| S.P.R Properties (N.I) Limited | Real estate | 2019 |
| S.Smyth Caravan Sales Ltd | Hospitality | 2003 |
| Saan Reddy Ltd | Hospitality | 2026 |
| Saandbanks Ltd | Construction | 2025 |
| Sabeni Ltd | Hospitality | 2024 |
| Sacred Circle Training Co CIC | Education | 2018 |
| Safe Zone Group Ltd | Other services | 2016 |
| Safety Advice Centre Limited | Administrative & support | 2002 |
| Safety First Consulting Ltd | Extraterritorial | 2024 |
| Sage Hospitality Limited | Hospitality | 2020 |
| Sagma Limited | Wholesale & retail | 2020 |
| Saigon Nails Bangor & Spa Ltd | Other services | 2023 |
| Sail School NI Limited | Arts & recreation | 2021 |
| Salaar Enterprise Limited | Wholesale & retail | 2025 |
| Sales Geek N.I. Ltd | Professional & scientific | 2022 |
| Salr Properties Limited | Real estate | 2024 |
| Salt & Pepper Catering Ltd | Manufacturing | 2008 |
| Salvare (NO1) Limited | Real estate | 2015 |
| SAM Fresh Food Ltd | Hospitality | 2023 |
| Samaki Limited | Professional & scientific | 2014 |
| Sammy Mellon and Sons Limited | Wholesale & retail | 1976 |
| Sandwell Valley Attractions Limited | Arts & recreation | 2025 |
| Sandymount Apartments Limited | Households | 1983 |
| Sanoodi Limited | Information & communication | 2007 |
| Sarpo Potatoes Limited | Agriculture & fishing | 2013 |
| Sarvari Research Trust | Professional & scientific | 2002 |
| Sasquatch Ltd | Professional & scientific | 2023 |
| Sawna Sauna CYF. | Other services | 2025 |
| Saxonhenge Limited | Transport & logistics | 2007 |
| Saysomethingin.Com CYF | Education | 2010 |
| Sazzleshark Ltd | Arts & recreation | 2023 |
| Sbarduno CIC | Education | 2025 |
| Sbeis Indian Restaurant Limited | Hospitality | 2025 |
| SBW Healthcare NI Ltd | Financial services | 2025 |
| SC Consulting (Ireland) Ltd | Construction | 2025 |
| SCA Play Inspections Ltd | Professional & scientific | 2023 |
| Scarlet P Limited | Real estate | 2010 |
| Scarlett's Rhosneigr Ltd | Wholesale & retail | 2014 |
| Scent by Mail Ltd | Wholesale & retail | 2016 |
| Scent by Mail NI 2 Ltd | Wholesale & retail | 2017 |
| Scent From Ireland Ltd | Manufacturing | 2016 |
| Scotia Industrial Abseiling Ltd | Construction | 2020 |
| Scott Willis Designs Ltd | Professional & scientific | 2019 |
| SCS Software Ltd | Professional & scientific | 2026 |
| SDG Productions Limited | Information & communication | 2020 |
| SDH Operations Ltd | Hospitality | 2018 |
| Sea JAY Marine Services Ltd | Manufacturing | 2023 |
| Sea View Tavern Limited | Hospitality | 2020 |
| Seacoast Safaris Limited | Transport & logistics | 2014 |
| Seacourt Print Workshop Limited | Arts & recreation | 1990 |
| Searchlink Bangor Limited | Professional & scientific | 2024 |
| Secure Zone UK Security Ltd | Administrative & support | 2025 |
| Seed and Grow Ltd | Real estate | 2026 |
| Seetloop Ltd | Information & communication | 2026 |
| Sefydliad Cefnogi Storiel | Education | 2026 |
| Seirios Enterprises Ltd | Administrative & support | 2022 |
| Seismic Geoscience Limited | Manufacturing | 2011 |
| Seismic Media Ltd | Information & communication | 2025 |
| Select Pubs Group Limited | Hospitality | 2019 |
| Semb Limited | Information & communication | 2020 |
| Send House Ltd | Health & social care | 2023 |
| Senderon Limited | Extraterritorial | 2018 |
| Sendmybag (NI) Limited | Transport & logistics | 2010 |
| Seshat Associates Ltd | Professional & scientific | 2025 |
| Shaftesbury Apartments II Limited | Extraterritorial | 2004 |
| Shaftesbury Apartments III Limited | Extraterritorial | 2004 |
| Shaftesbury Apartments IV Limited | Extraterritorial | 2004 |
| Shaftesbury Apartments Limited | Real estate | 2002 |
| Shaftesbury Apartments V Limited | Extraterritorial | 2004 |
| Shaftesbury Apartments V1 Limited | Extraterritorial | 2009 |
| Shaftesbury Manor Limited | Extraterritorial | 2004 |
| Shaftesbury Mews (NI) Limited | Extraterritorial | 2003 |
| Shah 113 (N.I.) Limited | Hospitality | 2016 |
| Shahin Balti & Kebab House Limited | Hospitality | 2018 |
| Shahin's Originals Ltd | Manufacturing | 2025 |
| Shamrock Homeowners Limited | Real estate | 2017 |
| Shapla (NI) Limited | Hospitality | 2013 |
| Share Impact Ltd | Administrative & support | 2017 |
| Share IT Savings Ltd | Real estate | 2012 |
| Sharman Manor Management Limited | Households | 2013 |