| DTG Solar Solutions Ltd | Wholesale & retail | 2025 |
| DU [Dare to Unlearn] Ltd | Professional & scientific | 2025 |
| Duffin Contracts Limited | Information & communication | 2014 |
| Duffin Holdings Ltd | Financial services | 2022 |
| Duffin Transport Ltd | Wholesale & retail | 2000 |
| Dunaird Limited | Construction | 2019 |
| Dunaverty Limited | Transport & logistics | 2022 |
| Duneany Consultancy Ltd | Financial services | 2024 |
| Dunfane Development Co. Limited | Construction | 1976 |
| Dunfane Farms Limited | Agriculture & fishing | 2017 |
| Dunlop Furniture Systems Ltd | Manufacturing | 2026 |
| Dunloy Development Partnership | Education | 2011 |
| Dunnygarran Farm Eggs Limited | Wholesale & retail | 2015 |
| Dunshane Limited | Construction | 2015 |
| Dunteige Shoot Ltd | Arts & recreation | 2019 |
| DWM Developments Limited | Construction | 2004 |
| Dyke Limited | Professional & scientific | 2003 |
| Dynamic Audio Visual Ltd | Information & communication | 2021 |
| Dynasty Retailers Ltd | Wholesale & retail | 2023 |
| E & O Investments Limited | Financial services | 2012 |
| E&A Reclamation Limited | Water & waste | 2020 |
| E-Breathe Ltd. | Manufacturing | 2016 |
| E-Cabs (N.I.) Limited | Transport & logistics | 2018 |
| E. Mcmullan Ltd | Professional & scientific | 2004 |
| E.V. Utilities Ltd | Construction | 2018 |
| Eagleson Construction Limited | Construction | 2019 |
| East Antrim Farming LLP | | 2006 |
| Eatsville Fish & Chips Limited | Hospitality | 2024 |
| EBB Coffee Ltd | Hospitality | 2025 |
| EBC Eggs Ltd | Agriculture & fishing | 2024 |
| Echo-Nomic Ltd | Other services | 2022 |
| Eclipse Nursery Store Limited | Wholesale & retail | 2013 |
| Eclypse Sales Limited | Wholesale & retail | 2016 |
| Ecomill Ltd | Manufacturing | 2025 |
| Ecomj Ltd | Wholesale & retail | 2023 |
| Econ Contracts Ltd | Construction | 2015 |
| Ed's Agri Limited | Water & waste | 2021 |
| Eden Playgroup Ltd | Education | 2024 |
| Eden Property & Landscape Services Ltd. | Administrative & support | 2019 |
| Eden Property Portfolio Ltd | Construction | 2021 |
| Edge Fabrications Limited | Construction | 2015 |
| Edmondson Estates Ltd | Real estate | 2017 |
| Eglish Potatoes Limited | Manufacturing | 2017 |
| Eighteen Lions Properties | Real estate | 1976 |
| Eirmon Trustee Limited | Financial services | 2021 |
| Elan Communications Ltd | Wholesale & retail | 2020 |
| Elan Group Consulting Ltd | Wholesale & retail | 2026 |
| Elan Property NI Ltd | Real estate | 2024 |
| Elder Drive Limited | Extraterritorial | 2016 |
| Electrical Construction and Maintenance (ECM) Limited | Construction | 2019 |
| Electrical Training (N.I.) Limited | Education | 1997 |
| Electricityworx Ltd | Construction | 2014 |
| Elemental Flow Towers Ltd | Professional & scientific | 2016 |
| Elevate One Step at a Time Limited | Health & social care | 2024 |
| Elginny Farm Limited | Agriculture & fishing | 2024 |
| Elite Gardens Limited | Other services | 2004 |
| Elite Lighting & Interiors Ltd | Wholesale & retail | 2018 |
| Ellen Reid Properties Limited | Real estate | 2021 |
| Ellis Civils Works Limited | Construction | 2014 |
| Elluke Limited | Real estate | 2021 |
| Elmac Contracts | Construction | 2014 |
| Elmvale Properties Limited | Real estate | 2007 |
| Elmwood Construction & Fitout Limited | Construction | 2023 |
| Elroi Automation Solutions Ltd | Professional & scientific | 2022 |
| Eluxe Beauty Limited | Other services | 2017 |
| Emc.Tv Limited | Information & communication | 2022 |
| Emerald Electrical Ltd | Construction | 2021 |
| Emfira Ltd | Professional & scientific | 2025 |
| Energy to Burn Ltd | Education | 2024 |
| Ennismore Hall Services Limited | Extraterritorial | 2004 |
| Ensurav Ltd | Information & communication | 2026 |
| Entity Global Limited | Professional & scientific | 2025 |
| EPL Construction Ltd | Construction | 2018 |
| Epops Ltd | Health & social care | 2020 |
| Equine Elite Ltd | Other services | 2024 |
| EQUITY10 Properties Ltd | Real estate | 2025 |
| Erah Limited | Real estate | 2021 |
| Erudite Knowledge Trade Ltd | Wholesale & retail | 2024 |
| Eshton Farms Ltd | Agriculture & fishing | 2024 |
| Esler Enterprise Ltd | Hospitality | 2023 |
| Estate and Titanic Ltd | Manufacturing | 2020 |
| Estate Connect Limited | Other services | 2023 |
| Estco NI Ltd | Construction | 2008 |
| Etherson Travel Ltd | Transport & logistics | 2017 |
| Europass Ireland Limited | | 2000 |
| Eventco Hospitality Limited | Hospitality | 2017 |
| Eventco Marquees Limited | Administrative & support | 2015 |
| Everbloome Petal Imports Ltd | Wholesale & retail | 2026 |
| Evloria Ventures Ltd | Wholesale & retail | 2025 |
| Evoke Counselling Ltd | Health & social care | 2024 |
| Excel Elevators Ltd | Construction | 2012 |
| Excel Leadership International CIC | Professional & scientific | 2022 |
| Excel Roofing and Cladding Products Ltd | Construction | 2014 |
| Excelttc Limited | Information & communication | 2026 |
| Expert Clean Ltd | Administrative & support | 2022 |
| Export Edge International Limited | Professional & scientific | 1994 |
| Extra Care for Elderly People Limited | Health & social care | 1986 |
| EYE Change Consultancy Ltd | Professional & scientific | 2014 |
| F. J. Mccartney & Crawford (Insurances) Ltd | Financial services | 2019 |
| F8 Holding Company | Financial services | 2020 |