| Bromus Limited | Real estate | 2025 |
| Brooke Limited | Real estate | 1973 |
| Brunchers Fine Foods Ltd | Manufacturing | 2024 |
| Buck and Lloyd (Sheffield) Limited | Manufacturing | 2004 |
| Buckingham Educational Experiences Limited | Administrative & support | 2020 |
| Buddy Ventures Ltd | Hospitality | 2024 |
| Bullithorn Limited | Real estate | 2021 |
| Burgin Conservatories Ltd | Construction | 2013 |
| Burgin Properties Limited | Other services | 2017 |
| Burleigh Castle Lodges Limited | Hospitality | 2022 |
| Burleigh Golf Limited | Arts & recreation | 2022 |
| Butterton Cross Farm Limited | Other services | 2016 |
| Buxton Road Properties Limited | Households | 1998 |
| Byuk Ltd | Information & communication | 2019 |
| C.R. Cartledge Limited | Construction | 2005 |
| C2 Consultancy Services Ltd | Administrative & support | 2025 |
| Cadogan Squared Consulting Ltd | Professional & scientific | 2014 |
| Caduceus Trading Limited | Other services | 2024 |
| Calver Properties Limited | Real estate | 2017 |
| Caroline Hutson-Environmental Consultancy Limited | Professional & scientific | 2012 |
| Castle Hill Management (Bakewell) Limited | Real estate | 2004 |
| Catch 32 Limited | Hospitality | 2025 |
| Catcliffe Realty Ltd | Real estate | 2000 |
| Cauliflower Club Ltd | Hospitality | 2018 |
| CEM Property Management Services Ltd | Real estate | 2019 |
| Cfco Limited | Real estate | 2019 |
| CHANGE365 Limited | Professional & scientific | 2014 |
| Charco 1527 Limited | Financial services | 2020 |
| Charco 2014 Limited | Construction | 2013 |
| Charco 2020 Limited | Construction | 2014 |
| Chatsworth Estate Trading Limited | Hospitality | 1986 |
| Chatsworth Estates Company(The) | Real estate | 1926 |
| Chatsworth Holdings Limited | Professional & scientific | 1983 |
| Chatsworth House Enterprises Limited | Administrative & support | 2014 |
| Chatsworth House Trust | Arts & recreation | 1981 |
| Chatsworth Locksmiths Ltd | Administrative & support | 2019 |
| Cherry Blossom Retreat Ltd | Hospitality | 2025 |
| Chloe's Bakehouse & Coffee Shop Limited | Hospitality | 2024 |
| Chris Mason Limited | Transport & logistics | 2009 |
| Chris Stone Property Maintenance Limited | Construction | 2013 |
| Chris' Automotive Electrical Shop Ltd | Wholesale & retail | 2019 |
| Chris' Automotive Restoration Shop Ltd | Wholesale & retail | 2019 |
| Chroey Ltd | Real estate | 2025 |
| Church Lane Farm Limited | Real estate | 2023 |
| Cliffmonsal Limited | Hospitality | 2014 |
| CLP Bakewell Limited | Hospitality | 2014 |
| Codel International Limited | Manufacturing | 1982 |
| Colorset North Ltd | Manufacturing | 2018 |
| Column Systems Limited | Information & communication | 1994 |
| Company 17 Limited | Construction | 2024 |
| Company 18 Limited | Construction | 2024 |
| Coneplace Limited | Professional & scientific | 2000 |
| Connaught Project Management Ltd. | Information & communication | 1991 |
| Consolidated European Holdings PLC | Mining & quarrying | 1990 |
| Cookshops (UK) Limited | Wholesale & retail | 2013 |
| Coopers PUB Company Limited | Hospitality | 2006 |
| Copyorder Limited | Hospitality | 1994 |
| Cornriggs Consulting Ltd | Other services | 2026 |
| Corrigan Engineering and Technology Limited | Professional & scientific | 2022 |
| Cosy Corner Relocations Ltd | Real estate | 2026 |
| Countertrade Limited | Wholesale & retail | 2016 |
| Country Cladding Limited | Manufacturing | 1996 |
| Coverland Holdings Limited | Financial services | 2024 |
| Coverland UK Limited | Real estate | 2000 |
| CR Butterworth Limited | Professional & scientific | 2003 |
| Cricstudio @ S20 the Boundary Ltd | Wholesale & retail | 2023 |
| Crow PIE Marketing Limited | Hospitality | 2008 |
| CS Catering Solutions Ltd | Hospitality | 2020 |
| CS Contact Centre Solutions Limited | Information & communication | 2013 |
| D Butterworth Plumbing & Heating Ltd | Construction | 2014 |
| D H Accounting Limited | Professional & scientific | 2015 |
| D P Property Investments Limited | Real estate | 2007 |
| D P Young Site Services Limited | Professional & scientific | 2011 |
| D S Needham Ltd | Construction | 2017 |
| D. C. Hoult Limited | Manufacturing | 1998 |
| D. H. Control Systems Limited | Information & communication | 1997 |
| D.N.D.Spibey Limited | Agriculture & fishing | 2014 |
| Daily Bathrooms Ltd | Construction | 2024 |
| Dalby Studio Ltd | Professional & scientific | 2026 |
| David George Bakewell Limited | Other services | 2009 |
| David George Kegworth Limited | Other services | 2009 |
| David White Associates Limited | Professional & scientific | 2003 |
| Dawa UX Consulting Limited | Other services | 2010 |
| Dbjf Ltd | Construction | 2021 |
| Dcmap Ltd | Professional & scientific | 2025 |
| Dead Canary Bakewell Limited | Hospitality | 2024 |
| Delectable Bakes Ltd | Manufacturing | 2026 |
| Derby Diocesan Academy Trust | Education | 2014 |
| Derbyshire Aggregates Limited | Mining & quarrying | 1984 |
| Derbyshire and London Limited | Professional & scientific | 2016 |
| Derbyshire Care Group Limited | Health & social care | 2025 |
| Derbyshire Dales Council for Voluntary Service | Other services | 2002 |
| Derbyshire Detailing Ltd | Wholesale & retail | 2025 |
| Derbyshire Holiday Cottage Services Limited | Hospitality | 2011 |
| Derbyshire Manor House Limited | Hospitality | 2016 |
| Derbyshire Resin Driveways Limited | Construction | 2019 |
| Derwent Energy Services Ltd | Professional & scientific | 2025 |
| Derwent Venue Limited | Hospitality | 2010 |
| Devon Malcolm Associates Limited | Manufacturing | 2015 |
| Devonshire Commercial Property Limited | Real estate | 2019 |