| Rymax Estates USA Limited | Real estate | 2005 |
| S & C Landscaping and Groundworks Ltd | Water & waste | 2025 |
| S & I Home Care Limited | Health & social care | 2026 |
| S H Accountancy Kent Ltd | Professional & scientific | 1991 |
| S&L Building and Landscaping Limited | Construction | 2021 |
| S&S Home Sales Ltd | Other services | 2026 |
| S.E. King's Building Limited | Construction | 2018 |
| Sabai Sabai Ltd | Health & social care | 2021 |
| Sabai Sabai Rental Limited | Real estate | 2025 |
| Sabbas Imports Limited | Wholesale & retail | 2018 |
| Safe Appliance UK Ltd | Administrative & support | 2012 |
| Safety Assured International Ltd | Extraterritorial | 2014 |
| Safety EYE Ltd | Real estate | 2023 |
| Safety-Light Ltd | Wholesale & retail | 2024 |
| Safetymark Certification Services Limited | Professional & scientific | 2000 |
| Sairam Linga Capital Limited | Real estate | 2026 |
| Sajha SL Co Limited | Hospitality | 2024 |
| Salm Property Ltd | Real estate | 2023 |
| Salus Homes (Residential) Limited | Professional & scientific | 2017 |
| Salus Homes Limited | Real estate | 2013 |
| Salvaterra Limited | Wholesale & retail | 2023 |
| Samon Films Limited | Information & communication | 2012 |
| Samson FOX Limited | Real estate | 2020 |
| Sancto Merricks Financial Planning Limited | Financial services | 2009 |
| Sands Publishing Solutions LLP | | 2001 |
| Santos Diner Ltd | Hospitality | 2018 |
| Sapphire Capital Investments Limited | Real estate | 2017 |
| Saracen Horse Feeds Ltd | Manufacturing | 2010 |
| Sarah Pfly Ltd | Professional & scientific | 2020 |
| Saxon Shore Developments Limited | Real estate | 2004 |
| Scaffapp UK Ltd | Information & communication | 2025 |
| Scarlet London Limited | Wholesale & retail | 2023 |
| Scients Ltd | Wholesale & retail | 2024 |
| Scorgie Engineering Ltd | Information & communication | 2025 |
| Scotrar Solutions Limited | Construction | 2011 |
| Scout AI Limited | Information & communication | 2025 |
| SD Analytics Limited | Administrative & support | 2017 |
| Sealey Commercial Cleaning Ltd | Administrative & support | 2024 |
| Seasons Garden Chinese Limited | Hospitality | 2025 |
| Seasons Garden DS Limited | Hospitality | 2023 |
| Seaview Holiday Rentals Limited | Hospitality | 2022 |
| SEE Property Ownership Limited | Real estate | 2021 |
| Seed Start UPS Ltd | Professional & scientific | 2022 |
| Segu UK Limited | Administrative & support | 2013 |
| Selectra Ltd | Real estate | 2018 |
| Sellvix Ltd | Wholesale & retail | 2025 |
| Semezana Consulting Limited | Professional & scientific | 2001 |
| SEN Tuition Limited | Education | 2025 |
| Sena Property Investments Limited | Real estate | 2024 |
| Senlac House Battle Ltd | Hospitality | 2016 |
| Sense of Security Limited | Construction | 2003 |
| Sentanon Ltd | Information & communication | 2022 |
| Serious Sparks Ltd | Construction | 2023 |
| Seven Sea Coastal Retreat LLP | | 2022 |
| Seymour Hire Limited | Wholesale & retail | 1986 |
| Seymour Road Properties Limited | Professional & scientific | 2004 |
| SG Systems (UK) Limited | Manufacturing | 2003 |
| SGS Landscaping Ltd | Professional & scientific | 2019 |
| Shade of ME Ltd | Wholesale & retail | 2025 |
| Shield Water Ltd | Water & waste | 2025 |
| Shoor Developments Limited | Real estate | 2024 |
| Shoosmith Heating & Plumbing Limited | Construction | 2014 |
| Shopperapp Ltd | Wholesale & retail | 2025 |
| Shutup Shutters Ltd | Construction | 2018 |
| Siam Consulting Ltd | Professional & scientific | 2024 |
| SIG Consultancy Services Ltd | Professional & scientific | 2023 |
| SIG Property Limited | Real estate | 2022 |
| Signs and More Limited | Manufacturing | 2018 |
| Silk Roadz Ltd | Wholesale & retail | 2024 |
| Silver Booth Ltd | Wholesale & retail | 2022 |
| Sirenia Ltd | Professional & scientific | 2011 |
| Sisco Services Limited | Administrative & support | 2007 |
| Sit.Stay.Vacay Ltd | Agriculture & fishing | 2025 |
| SJF Estimating & Cost Consulting Ltd | Professional & scientific | 2026 |
| SJH Snodland Limited | Real estate | 2022 |
| Sjhc Bramley Ltd | Real estate | 2026 |
| Sjhc Holtwood Ltd | Real estate | 2026 |
| Sjhc Investments Ltd | Financial services | 2025 |
| Sjhc Larkfield Ltd | Real estate | 2025 |
| Sjhc MAY Ltd | Real estate | 2026 |
| Sjhc Peel Ltd | Real estate | 2026 |
| Sjhc Tovil Ltd | Real estate | 2025 |
| Sjhcr Pear Ltd | Real estate | 2026 |
| Sjhcr Spillway Ltd | Real estate | 2026 |
| SJM Fruit Brokers Limited | Wholesale & retail | 2001 |
| Skeuomorph Limited | Arts & recreation | 2016 |
| Skyhook Adventure Limited | Wholesale & retail | 2017 |
| Slalom Productions Limited | Administrative & support | 2007 |
| Slaybyyemi Limited | Wholesale & retail | 2025 |
| Slipform Specialist Limited | Construction | 2025 |
| Smallmans Holdings Ltd | Real estate | 2025 |
| Smart Courier Ltd | Transport & logistics | 2017 |
| Smart Pickle Ltd | Professional & scientific | 2018 |
| Smart Services South East Limited | Other services | 2022 |
| Smart Start Admin Ltd | Administrative & support | 2025 |
| Smarts Darts Ltd | Administrative & support | 2019 |
| Smileshines (Aylesford) Ltd | Health & social care | 2010 |
| Smileshines (Beckenham) Ltd | Health & social care | 2019 |
| Smiths Fire & Security Ltd | Administrative & support | 2024 |
| SMR Sales Limited | Construction | 2021 |