| Snaps Games Axminster Ltd | Wholesale & retail | 2025 |
| Snaps Games Ltd | Wholesale & retail | 2025 |
| Society of Extreme Expedition & Wilderness Medicine | Other services | 2016 |
| Society of Floristry Limited(The) | Other services | 1951 |
| Solapak Development Limited | Professional & scientific | 2019 |
| Solapak Systems Limited | Manufacturing | 2002 |
| Solar EX Solutions Limited | Extraterritorial | 2015 |
| Somerdawn Limited | Professional & scientific | 2001 |
| Somerset Tile and Stone Limited | Wholesale & retail | 2019 |
| Sourced Nationwide Ltd | Other services | 2018 |
| South Chard Customs Ltd | Professional & scientific | 2023 |
| South West Removals Ltd | Transport & logistics | 2020 |
| South West Renewables (Devon) Limited | Wholesale & retail | 2020 |
| Southern Filters Limited | Wholesale & retail | 2000 |
| Southern Fish Industry Training Academy Ltd | Education | 2015 |
| Southwest Records Limited | Arts & recreation | 1998 |
| Spearhead Optimisation Solutions Ltd | Information & communication | 2021 |
| Spectre Performance Ltd | Health & social care | 2022 |
| ST. Georges Properties (Axminster) Limited | Construction | 1999 |
| ST. Mary's Axminster (Management) Limited | Households | 1987 |
| Stan Kowal Limited | Construction | 2003 |
| Starnaborg Limited | Real estate | 2024 |
| Start a Chat Ltd | Professional & scientific | 2021 |
| STC Stores Ltd | Wholesale & retail | 2016 |
| Stealth Human Performance Ltd | Professional & scientific | 2024 |
| Stephen Thirlwell Ltd. | Wholesale & retail | 2002 |
| Stewart Lets Ltd | Real estate | 2020 |
| Stinchcombe Plant Limited | Administrative & support | 2014 |
| Stones Property Rental Limited | Real estate | 2025 |
| Stork Maritime Limited | Transport & logistics | 2017 |
| Storykeepers Ltd | Wholesale & retail | 2024 |
| Streamside Management Company Limited | Households | 2010 |
| Stronghold Productions Limited | Arts & recreation | 2006 |
| Styles & Brown Ltd | Wholesale & retail | 1998 |
| Styles & Brown Property Holdings Ltd | Real estate | 2015 |
| Summer 66 Limited | Hospitality | 2024 |
| Summer Tree Limited | Hospitality | 2017 |
| Summerlands Management Company Limited | Households | 2007 |
| Summerleaze Vets Limited | Professional & scientific | 2017 |
| Sunday School Limited | Other services | 2005 |
| SVM Media Law Limited | Professional & scientific | 2019 |
| Sweeting Body Repairs Limited | Wholesale & retail | 2024 |
| Swizzle and Friends Limited | Manufacturing | 2018 |
| Swordcrown Caravans Limited | Wholesale & retail | 2021 |
| Sylva Holdings Ltd | Financial services | 2026 |
| Target Sports Centre Ltd | Arts & recreation | 2009 |
| Taste the Air Limited | Administrative & support | 2023 |
| Tastes Alive LLP | | 2025 |
| Tasty Thais Ltd | Hospitality | 2024 |
| TBL Associates Ltd | Financial services | 2022 |
| Tcas Ltd. | Professional & scientific | 2002 |
| TE AWA Limited | Information & communication | 2022 |
| Teraime Ltd | Professional & scientific | 2019 |
| Tewson Limited | Construction | 2014 |
| Thai Food to Go Ltd | Hospitality | 2021 |
| THE ALE Way (Axminster) Ltd | Hospitality | 2024 |
| THE ALE Way Ltd | Hospitality | 2019 |
| THE Bakehouse (Axminster) Ltd | Manufacturing | 2018 |
| THE Beauty DEN Taunton Ltd | Other services | 2024 |
| THE Boar's Head Company Limited | Other services | 1971 |
| THE Body Sculpting Collective by Evie Ltd | Health & social care | 2026 |
| THE Brogue Artist Limited | Arts & recreation | 2024 |
| THE Cafe at the Store Ltd | Hospitality | 2025 |
| THE Child Development Centre Ltd | Health & social care | 2010 |
| THE Clock Cafe (Fraser) Ltd | Hospitality | 2017 |
| THE Community Waffle House CIC | Hospitality | 2018 |
| THE Company Coach Ltd. | Education | 1991 |
| THE Copper Mint Ltd | Manufacturing | 2010 |
| THE Dorset Cupboard Company Limited | Manufacturing | 2013 |
| THE Farmhouse Studio Ltd | Professional & scientific | 2018 |
| THE Folly Nursery Limited | Education | 2011 |
| THE Heritage Coast Building Company Limited | Construction | 2003 |
| THE Inclusion Agency CIC | Education | 2019 |
| THE Lamb Inn Ltd | Hospitality | 2011 |
| THE Lewesian Limited | Information & communication | 2021 |
| THE Melbury Skin Clinic Ltd | Health & social care | 2022 |
| THE Old Dairy Catering Company Ltd | Hospitality | 2018 |
| THE Organic Cure Ltd | Manufacturing | 2022 |
| THE Otterhead Estate Trust Company Limited | Education | 2006 |
| THE Padel Unit Ltd | Arts & recreation | 2026 |
| THE Peoples Court Ltd | Public administration | 2019 |
| THE Resort Alliance Limited | Professional & scientific | 2024 |
| THE Shrubbery Apartment Management Limited | Households | 2000 |
| THE Shrubbery Management Limited | Households | 2000 |
| Thomas Whitty Rugs and Carpets Limited | Manufacturing | 2022 |
| Three Counties Pest Control Ltd | Administrative & support | 2021 |
| Tick Tocks (Axminster) Ltd | Education | 2004 |
| Tidelym Ltd | Education | 2021 |
| Tiffins Limited | Manufacturing | 2023 |
| Tija Holdings Ltd | Financial services | 2016 |
| Timbersmiths Ltd | Manufacturing | 2016 |
| Time for YOU East Devon and West Dorset Ltd | Administrative & support | 2020 |
| Timegalore Ltd | Information & communication | 2012 |
| Timeshare Council | Other services | 1990 |
| Tinct Ltd | Professional & scientific | 2011 |
| Tjmcguire Hospitality Ltd | Hospitality | 2022 |
| TK Tennis Academy Ltd | Arts & recreation | 2017 |
| TMH Buildings Limited | Real estate | 2021 |
| TMH Restorative Limited | Health & social care | 2015 |
| TOM Southgate Building & Carpentry Limited | Construction | 2019 |