| Eco Blast (NE) Ltd | Administrative & support | 2022 |
| Eco Home Electrics Ltd | Construction | 2011 |
| Eco Pizza Ltd | Hospitality | 2023 |
| Ecospark Cleaning Ltd | Administrative & support | 2025 |
| Eden 12 Ltd | Real estate | 2025 |
| Eden 13 Ltd | Real estate | 2025 |
| Eden 14 Ltd | Real estate | 2025 |
| Eden 15 Ltd | Real estate | 2025 |
| Eden 3 Ltd | Real estate | 2024 |
| Eden 4 Ltd | Real estate | 2025 |
| Eden 6 Ltd | Real estate | 2024 |
| Eden 9 Ltd | Real estate | 2024 |
| EDEN1 North Ltd | Real estate | 2025 |
| Edinburgh at Home Limited | Other services | 2012 |
| Edpm Ltd | Professional & scientific | 2022 |
| Eileen Grace Limited | Wholesale & retail | 1994 |
| Electronic Security Solutions North East Limited | Administrative & support | 2017 |
| Eliaine Enterprises Ltd | Wholesale & retail | 2020 |
| Elite Paving Solutions Ltd | Administrative & support | 2025 |
| Embargoed Turkish Cypriots Limited | Other services | 2026 |
| Emcim Limited | Professional & scientific | 2022 |
| Emmex Freight Services Ltd. | Transport & logistics | 1997 |
| Empire Court (Whitley Bay) Management Company Limited | Households | 2018 |
| Energy Tuning Ltd | Manufacturing | 2008 |
| Enspire Design Limited | Other services | 1997 |
| Eplop Ltd | Wholesale & retail | 2019 |
| Escape Family Support Limited | Health & social care | 1996 |
| Esel Pizza Ltd | Hospitality | 2025 |
| Eshott School of Flying Ltd | Education | 2019 |
| ESL Electrical Installations Ltd | Construction | 2024 |
| ESL Trading Ltd | Wholesale & retail | 2025 |
| Essdema Ltd | Professional & scientific | 2019 |
| Essential Beauty Academy (North East) Limited | Education | 2016 |
| Essor Seven Ltd | Wholesale & retail | 2025 |
| EW Estates Ltd | Real estate | 2020 |
| Exalt Properties Limited | Real estate | 2020 |
| Ezecoms Ltd | Information & communication | 2019 |
| F&W Properties (NE) Ltd | Households | 2021 |
| Fairbairn Mechanical Ltd | Mining & quarrying | 2014 |
| Fairbairn Property Investment Limited | Real estate | 2009 |
| Family Pizza Ltd | Hospitality | 2026 |
| Fbgl Limited | Arts & recreation | 2023 |
| Financial Evolution Limited | Professional & scientific | 2004 |
| First Agent Ltd | Real estate | 2025 |
| First Image Ltd | Construction | 2009 |
| Fithub Academy Ltd | Information & communication | 2026 |
| Five Camperdown Limited | Real estate | 2019 |
| Flexie Ltd | Administrative & support | 2024 |
| Flyfishnorth Ltd | Wholesale & retail | 2018 |
| Flyhi Relax Ltd | Other services | 2018 |
| Fmbl Ltd | Real estate | 2025 |
| FOODPOINT7 Ltd | Hospitality | 2025 |
| Fords Fencing Contractors Ltd | Construction | 2019 |
| Forest Hall Maintenance Ltd | Construction | 2019 |
| Forest Hall Sales LLP | | 2013 |
| Forge Leisure (UK) Limited | Manufacturing | 2007 |
| Forget ME NOT Homecare Services Ltd | Health & social care | 2018 |
| Foster Davison Ltd | Real estate | 2023 |
| Foundry Hydraulic Services Limited | Professional & scientific | 1985 |
| Four Camperdown Limited | Real estate | 2015 |
| Freedom Consultants KM Ltd | Professional & scientific | 2022 |
| Freedom Payments Ltd | Professional & scientific | 2026 |
| Friedfix Limited | Hospitality | 2025 |
| Furniture 4 U NE Limited | Wholesale & retail | 2015 |
| G & V Properties (NE) Ltd | Households | 2021 |
| G B Glazing & Joinery Limited | Construction | 2023 |
| G Charlton Ltd | Mining & quarrying | 2020 |
| G. Phillips Heating and Solar Services Ltd | Construction | 2003 |
| G.B.M. Motors Alnwick Ltd. | Wholesale & retail | 2012 |
| GAL Events Limited | Administrative & support | 2017 |
| Garden Grafters Northumberland Limited | Administrative & support | 2025 |
| Gascoigne Farms Limited | Agriculture & fishing | 1997 |
| GB Flooring (North East) Limited | Wholesale & retail | 2008 |
| GC NDT Inspection Services Ltd | Mining & quarrying | 2017 |
| Geet Walla Ltd | Wholesale & retail | 2025 |
| GEM Heat Ltd | Construction | 2023 |
| Geomatics UK Limited | Construction | 2009 |
| George Mactec Ltd | Mining & quarrying | 2020 |
| GF & GD Properties Limited | Construction | 2024 |
| GF Ashington Limited | Hospitality | 2022 |
| GG and Sons Ltd | Wholesale & retail | 2023 |
| Ghyllheugh Estates Limited | Administrative & support | 2016 |
| Gialinh Hana Ltd | Other services | 2019 |
| Giant Stride OIL Ltd | Wholesale & retail | 2025 |
| Gib's Grill Limited | Wholesale & retail | 2007 |
| Gibbins Fabrication and Inspection Services Limited | Manufacturing | 2013 |
| GK Roofing & Property Maintenance Ltd | Construction | 2020 |
| GKP Solutions Ltd | Households | 2004 |
| GKS Limited | Other services | 2005 |
| Glen Miller Independent Funeral Directors Limited | Health & social care | 2013 |
| Glendale Motor Company Limited | Wholesale & retail | 2005 |
| Glentons Bakery Limited | Manufacturing | 2014 |
| Global Contracting Direct (GCD) Limited | Professional & scientific | 2015 |
| Global Gourmet Store Ltd | Wholesale & retail | 2025 |
| GM Alternative Provision Ltd | Administrative & support | 2023 |
| Gmarr Engineering Ltd | Professional & scientific | 2020 |
| GMH Joinery Ltd | Construction | 2026 |
| Go Star Blinds Manufacturing Ltd | Manufacturing | 2020 |
| Gold Trading and Investments Ltd | Financial services | 2025 |
| Golden Fish Bar Ltd | Hospitality | 2026 |