| DPS Property Limited | Construction | 2022 |
| Dqmcsolutions Limited | Administrative & support | 2016 |
| DR Business Solutions Limited | Professional & scientific | 2022 |
| DR Coaching Collective Ltd | Education | 2025 |
| DR Deanne Bell Psychology Ltd | Health & social care | 2022 |
| DR Elena's Aesthetics Limited | Other services | 2023 |
| DR Fire Door Consultants Ltd | Construction | 2018 |
| DR Priya Dental and Aesthetics Ltd | Health & social care | 2021 |
| DR Reddy's Health and Wellness Limited | Health & social care | 2026 |
| DR Rizwan Ahmed Ltd | Education | 2023 |
| DR Smilee Holding Ltd | Financial services | 2025 |
| DR Smilee Investment Ltd | Real estate | 2025 |
| DR Smilee Ltd | Health & social care | 2025 |
| DR TK Locum Ltd | Health & social care | 2022 |
| DR Zara Sadiq Ltd | Health & social care | 2025 |
| DR. H. S. Sindher Limited | Health & social care | 2014 |
| Dragon Soul TCG Ltd | Wholesale & retail | 2024 |
| Dragtone Group Ltd | Administrative & support | 2026 |
| Dragusin Ovidiu Ltd | Transport & logistics | 2022 |
| Drain & Sewage Pumping System Services Limited | Water & waste | 2009 |
| Drain King Limited | Water & waste | 2002 |
| Drainline Construction Ltd | Construction | 2017 |
| Drake Developments (Kent) Limited | Construction | 2015 |
| Drax Aerospace Limited | Manufacturing | 1980 |
| DRC Renewables Limited | Construction | 2023 |
| Dream Coder Solutions Ltd | Professional & scientific | 2015 |
| Dream House Property Services Ltd | Construction | 2025 |
| Dream Interiors Ltd | Extraterritorial | 2025 |
| Dream Super Mall Ltd | Wholesale & retail | 2025 |
| Dream Vac-Ex Ltd | Construction | 2025 |
| Dream Web Ideas Ltd | Information & communication | 2025 |
| Dreamelement Limited | Professional & scientific | 2017 |
| Dreams Events Group Limited | Professional & scientific | 2021 |
| Drew Family Property Ltd | Real estate | 2022 |
| Drewes Access Limited | Construction | 2026 |
| DRH Engineering Ltd | Construction | 2023 |
| Drift Road MOT Limited | Wholesale & retail | 2005 |
| Driftwood Cafe Limited | Hospitality | 2017 |
| Drip Drop and Plop Limited | Construction | 2024 |
| Drive Tech Solutions Ltd | Wholesale & retail | 2007 |
| Drivermedics UK Ltd | Health & social care | 2021 |
| Driversity Risk Management (South) Limited | Education | 2021 |
| Driving Equality CIC | Education | 2025 |
| Driving Holidays Limited | Administrative & support | 2002 |
| Drombeg Estates Limited | Construction | 1998 |
| Drombeg Investments Limited | Financial services | 1956 |
| Dronix Ltd | Wholesale & retail | 2020 |
| Drop & Go Self Service Launderette (Ashford) Limited | Other services | 2026 |
| Drop 'N' Go Laundry (Ashford) Ltd | Other services | 2023 |
| Drop 'N' Go Laundry Services Ltd | Extraterritorial | 2016 |
| DROP2DOT Ltd | Transport & logistics | 2024 |
| DRY Ice Nationwide Limited | Manufacturing | 2019 |
| Drying and Restoration Services Ltd | Construction | 2023 |
| DS European Ltd | Transport & logistics | 2024 |
| DS Plastering and Artexing Ltd | Construction | 2009 |
| DS Security and Training Solutions Limited | Administrative & support | 2022 |
| DS Spring Bidco Limited | Financial services | 2019 |
| DS Spring Midco 1 Limited | Financial services | 2019 |
| DS Spring Midco 2 Limited | Financial services | 2019 |
| Ds&N Limited | Construction | 2011 |
| DSC Carpet & Flooring Ltd | Wholesale & retail | 2021 |
| DSH Consult Ltd | Information & communication | 2018 |
| DSM Detailing Ltd | Administrative & support | 2025 |
| DSM Telecoms Consulting Ltd | Information & communication | 2026 |
| DSP Aggregates Ltd | Water & waste | 2012 |
| DSP Builders and Contractors Ltd | Water & waste | 2012 |
| Dsta Investments Limited | Real estate | 2017 |
| Dstaffing Ltd | Administrative & support | 2019 |
| DSZ Consultancy Ltd | Health & social care | 2024 |
| DT Ransley Contractors Ltd | Construction | 2025 |
| DTA Consulting (S.E.) Limited | Professional & scientific | 2018 |
| DTA2Z Limited | Professional & scientific | 2022 |
| Dthapa Ltd | Health & social care | 2022 |
| Dtox Consulting Limited | Administrative & support | 2018 |
| Dtsc Construction Ltd | Construction | 2021 |
| Dual Aspect EOT Limited | Administrative & support | 2025 |
| Dual Aspect Glass Ltd | Wholesale & retail | 2011 |
| Dual Aspect Holdings Ltd | Financial services | 2020 |
| Dual Aspect Home Improvements Ltd | Wholesale & retail | 2016 |
| Dualrip Holdings Ltd | Information & communication | 2025 |
| DUB Breaks Ltd | Arts & recreation | 2024 |
| Dubor UK Limited | Wholesale & retail | 2022 |
| DUE South East Services Limited | Administrative & support | 2012 |
| Dumi Senda Ltd | Other services | 2018 |
| Dunaire Ltd | Hospitality | 2019 |
| Dunbar Solicitors Limited | Professional & scientific | 2010 |
| Dungeness Snack Shack Limited | Hospitality | 2020 |
| Dunrow (Builders & Suppliers) Limited | Construction | 1975 |
| DUO Technology Ltd | Information & communication | 2014 |
| Duoapp Limited | Information & communication | 2022 |
| Duovista LLP | | 2024 |
| Duprez Consulting Limited | Administrative & support | 2015 |
| Durable Contracts Limited | Construction | 2007 |
| Durable Contracts Roofing Limited | Construction | 1976 |
| Duramen Consulting Ltd | Agriculture & fishing | 2003 |
| Durland Care Limited | Real estate | 2017 |
| Duvy Properties Limited | Real estate | 2025 |
| DV Consultancy Ltd | Professional & scientific | 2024 |
| Dvine Carpentry & Kitchens Ltd | Construction | 2018 |
| DVS Tuning Limited | Wholesale & retail | 2011 |