| R & W Construction Services Limited | Construction | 2023 |
| R Hughes Power Services Limited | Construction | 2026 |
| R N M Barnes Limited | Construction | 2022 |
| R Roberts Brickworks and Building Services Limited | Construction | 2019 |
| R W Morgan Limited | Construction | 2002 |
| R&M Construction Utilities Ltd | Construction | 2018 |
| Radfordhr Ltd | Administrative & support | 2026 |
| Radiant IT Solutions Ltd | Information & communication | 2026 |
| Radstan Limited | Hospitality | 2024 |
| Rahmaali Solutions Ltd | Public administration | 2020 |
| Rapid IT (Outsourcing Services) Ltd | Construction | 2019 |
| RAY of Light Solutions Ltd | Professional & scientific | 2020 |
| RAY Thomas MOT Centre Ltd | Wholesale & retail | 2018 |
| RCL Construction Ltd | Construction | 2024 |
| RDH Contractors Limited | Transport & logistics | 2010 |
| RDW Enterprises Ltd | Administrative & support | 2020 |
| Recordiau Rumble CYF | Information & communication | 2026 |
| Red Dragon IT Services Limited | Information & communication | 2006 |
| Red Engineers Limited | Construction | 2006 |
| Red Hospitality Ltd | Hospitality | 2020 |
| Red RUM Properties Limited | Real estate | 2023 |
| Red Tiger (UK) Ltd | Information & communication | 2010 |
| Redblue Commerce Ltd | Water & waste | 2023 |
| Redcoat Protection Group Ltd | Administrative & support | 2024 |
| Redkite Business Consulting Ltd | Information & communication | 2011 |
| Redline Carpentry Ltd | Construction | 2023 |
| Release and Rebuild Ltd | Education | 2020 |
| Renewable Developments (Wales) Ltd | Professional & scientific | 2009 |
| Renewables 4 Wales Limited | Extraterritorial | 2013 |
| Renovo Bespoke Interiors Ltd | Wholesale & retail | 2021 |
| Represent US Rural Ltd | Education | 2020 |
| Retail Link Wales Ltd | Other services | 2026 |
| Revs Motors Holdings Limited | Financial services | 2023 |
| Revs Motors Limited | Wholesale & retail | 2010 |
| Rhian Marie Photography Limited | Professional & scientific | 2026 |
| RHODRIWILLIAMS1113 Limited | Administrative & support | 2016 |
| RHT Excavator Parts Ltd. | Wholesale & retail | 2015 |
| RHW Renewable Heating Wales Ltd | Construction | 2021 |
| Richard Safadi Ltd | Wholesale & retail | 2011 |
| Ritson Design Services Limited | Professional & scientific | 1996 |
| RJ & GM Jones Limited | Administrative & support | 2003 |
| RJ Groundwork Contractors Limited | Construction | 2016 |
| RJ Rail & Civils Ltd | Construction | 2022 |
| RJK Automotive Solutions Ltd | Professional & scientific | 2018 |
| RJR Engineering Ltd | Construction | 2024 |
| RK Construction (Carmarthenshire) Limited | Construction | 2014 |
| RM Neurophysiology Limited | Health & social care | 2023 |
| Rmti Holdings Limited | Financial services | 2021 |
| RNA Group Limited | Financial services | 2016 |
| RNA Hire Services Limited | Extraterritorial | 2019 |
| RNA Plant Limited | Construction | 2002 |
| Roberts Concrete Limited | Manufacturing | 2014 |
| Robinsons Cleaning Ltd | Administrative & support | 2024 |
| Rominos Pizza Swansea Ltd | Hospitality | 2025 |
| Ronin Designs Limited | Manufacturing | 1997 |
| Rowan Evans Building Contractors Ltd | Construction | 2020 |
| Rowan Retreats Limited | Real estate | 2025 |
| Rowley & Price Limited | Real estate | 2011 |
| Rozi Pizza Ltd | Hospitality | 2021 |
| RQ Group Ltd | Professional & scientific | 2023 |
| Rrsa Carefree Limited | Administrative & support | 2016 |
| Rtcs Distributors Ltd | Wholesale & retail | 2020 |
| Ryda Building Ltd | Construction | 2017 |
| Rydex Import Ltd | Wholesale & retail | 2023 |
| S Whitecross Ltd | Construction | 2023 |
| S&N Trading (South Wales) Ltd | Hospitality | 2019 |
| S.D. Property (Swansea) Ltd | Real estate | 2018 |
| S.W. Community Services Ltd | Manufacturing | 2019 |
| Safe Steps Care Limited | Health & social care | 2025 |
| Safer Partnerships Project Ltd | Administrative & support | 2026 |
| Saib Takeaway Ltd | Hospitality | 2024 |
| Salient Intelligence Limited | Information & communication | 2020 |
| Sally Smith Limited | Administrative & support | 2003 |
| Saphire Cleaning Services Limited | Administrative & support | 2015 |
| Sash Hardware Limited | Extraterritorial | 2007 |
| Savannah Flame Ltd | Manufacturing | 2025 |
| Save Money CUT Carbon Ltd | Professional & scientific | 2012 |
| SCD Technical Solutions Ltd | Professional & scientific | 2021 |
| Scott Construction and Property Ltd | Construction | 2023 |
| SEL Property Limited | Households | 2024 |
| Seyon Convenience Ltd | Wholesale & retail | 2018 |
| Seyon Property Ltd | Real estate | 2020 |
| SFM Consulting Ltd | Information & communication | 2026 |
| Sgil Link CIC | Education | 2022 |
| Shaan Tandoori Takeaway Ltd | Hospitality | 2017 |
| Shadows Depression Support Group Limited | Other services | 2020 |
| SHE Scapes Landscaping & Maintenance Ltd | Administrative & support | 2026 |
| Sheq Sphere Ltd | Information & communication | 2026 |
| Shire Homes (Carms) Ltd | Construction | 2017 |
| Sieffre Holdings Limited | Extraterritorial | 2017 |
| Sigma Virtual Services Ltd | Administrative & support | 2023 |
| Silverline Aviation Ltd | Professional & scientific | 2023 |
| Simon Pritchard Physiotherapy Ltd | Other services | 2022 |
| Simplyseedz Limited | Manufacturing | 2014 |
| Singh & Co Group Ltd | Wholesale & retail | 2026 |
| Singh Jones Properties Ltd | Construction | 2023 |
| Siop Y Mynydd DU | Wholesale & retail | 2018 |
| Site Services Britain Limited | Water & waste | 2001 |
| SJ Camper Hire Limited | Administrative & support | 2022 |
| SJP Ventures Limited | Real estate | 2023 |