| Dragon FW Holdings Ltd | Financial services | 2024 |
| Dragon Plant & Tool Hire Limited | Administrative & support | 2019 |
| Dragon VW Events Limited | Arts & recreation | 2012 |
| Draig Designs Limited | Construction | 2025 |
| DRP + Co Accountants Limited | Professional & scientific | 2009 |
| Dsj's Landscaping & Groundworks Ltd | Administrative & support | 2026 |
| Dwelling and Drive Ltd | Real estate | 2025 |
| DWR (Cost Engineers) Ltd | Professional & scientific | 2013 |
| DY99 Ltd | Hospitality | 2024 |
| Dyffryn Pharmacy Limited | Wholesale & retail | 2002 |
| Dynevor Homes Limited | Construction | 2002 |
| E&Rl Meats Limited | Wholesale & retail | 2026 |
| E1ITEPROPERTIES Ltd | Real estate | 2024 |
| EAD Property Management Limited | Real estate | 2021 |
| Eage Store Ltd | Wholesale & retail | 2019 |
| Eang Enterprise Ltd | Wholesale & retail | 2020 |
| Eazy Heat Ltd | Construction | 2021 |
| EB Aggregates Limited | Wholesale & retail | 2013 |
| EBM Auto Solutions Limited | Wholesale & retail | 2024 |
| EC Performance Ltd | Wholesale & retail | 2025 |
| ECH Fabrications Ltd | Manufacturing | 2024 |
| Eco Smart Solutions Ltd | Professional & scientific | 2023 |
| Eco-Friendlyfinds C.I.C. | Wholesale & retail | 2025 |
| ECR Developments Limited | Construction | 2021 |
| Edal Holdings Limited | Financial services | 2015 |
| Edgar R Thomas Limited | Real estate | 2024 |
| Edutility Limited | Education | 2004 |
| Electestwales Ltd | Construction | 2019 |
| Electrical & Energy Solutions Swansea Ltd | Construction | 2025 |
| Elevate Wellness Ltd | Arts & recreation | 2024 |
| Elhalusu Limited | Real estate | 2024 |
| Elite Housing Solutions Ltd | Real estate | 2020 |
| Elite Planning Solutions Limited | Construction | 2014 |
| Elite Washes & Drainage Ltd | Administrative & support | 2019 |
| ELITE15 Limited | Financial services | 2026 |
| Elitexv Limited | Professional & scientific | 2025 |
| Elston Trading Ltd | Wholesale & retail | 2025 |
| Emark Limited | Administrative & support | 1993 |
| EMS Cabs Ltd | Transport & logistics | 2018 |
| EMT Precision Pipework Ltd | Manufacturing | 2023 |
| Enclosure TEC Ltd | Manufacturing | 2010 |
| Enclosureuk Limited | Manufacturing | 2013 |
| Energy Dynamic Model Ltd | Education | 2018 |
| Entrad UK Ltd | Wholesale & retail | 2021 |
| Enzo's Holdings Limited | Professional & scientific | 2004 |
| ERA Community Care Ltd. | Health & social care | 2021 |
| ERA Living Solutions Limited | Health & social care | 2009 |
| Escape Swansea Ltd | Arts & recreation | 2024 |
| Essjay Agencies Limited | Professional & scientific | 2002 |
| Euroflora Limited | Extraterritorial | 2016 |
| EV & Solar Solutions Ltd | Construction | 2023 |
| Evans Banks Planning Limited | Professional & scientific | 2020 |
| Evans Brothers (Bulk Haulage) Ltd | Transport & logistics | 2018 |
| Evans Brothers Bulk Tippers Ltd | Transport & logistics | 2024 |
| Evans Lettings and Sales Ltd | Real estate | 2018 |
| EVANS4WINDOWS Limited | Manufacturing | 2022 |
| Eventus Training & Events Ltd | Education | 2001 |
| Evsrow Developments Ltd | Real estate | 2021 |
| Express Lite Logistics Ltd | Transport & logistics | 2012 |
| Exquisite Oak Ltd | Construction | 2017 |
| Extra Time Advanced Football Coaching Limited | Other services | 2018 |
| Fade Away Tattoo Removal Ltd | Other services | 2023 |
| Family Property Hub Ltd | Real estate | 2025 |
| Featherlite Mouldings Ltd | Manufacturing | 2000 |
| Felinfach Management Company Limited | Real estate | 2006 |
| Ferry Laundry Services Limited | Other services | 2003 |
| Fferyllfa Tycroes CYF | Wholesale & retail | 2014 |
| Fforest Hill Limited | Arts & recreation | 2017 |
| Fiber Group Ltd | Manufacturing | 2022 |
| Fiela 32 Limited | Hospitality | 2022 |
| Filtercite Ltd | Mining & quarrying | 2016 |
| Fineline Production Designs Ltd | Arts & recreation | 2025 |
| Fire Safety Consultancy Services Ltd | Professional & scientific | 2025 |
| Firetile Heatshield Ltd | Other services | 2025 |
| FIT4EVER Limited | Wholesale & retail | 2020 |
| Flawless Skin Aesthetics Limited | Health & social care | 2025 |
| Fluce Limited | Agriculture & fishing | 2014 |
| Foresight Funding Solutions Limited | Financial services | 2017 |
| Forest Clays Limited | Professional & scientific | 1968 |
| Forza Commercial Ltd | Professional & scientific | 2025 |
| FOX Props Ltd | Information & communication | 2023 |
| Fraser Addis & Co Limited | Real estate | 2023 |
| Free Fones Select Limited | Transport & logistics | 2006 |
| Free Mobiles 4 U Ltd | Professional & scientific | 2005 |
| Freedom Online Ltd | Professional & scientific | 2019 |
| Freeman Fleet Hire Limited | Construction | 2025 |
| Fresh Productions Ltd | Other services | 2025 |
| Freshstart Care Ltd | Health & social care | 2019 |
| Friendly Advice Limited | Financial services | 2016 |
| FS Engineering and Surveying Services Limited | Construction | 2023 |
| Funky on Thrift Ltd | Wholesale & retail | 2023 |
| Fusion Fanaticz Limited | Hospitality | 2025 |
| Fynentro Consultancy Ltd | Information & communication | 2025 |
| G Bartlett Builders Ltd | Construction | 2021 |
| Gaia Hire Ltd | Energy | 2017 |
| Garco Limited | Professional & scientific | 2013 |
| Garden Utopia Limited | Manufacturing | 2020 |
| Garland Properties (Ammanford) Limited | Real estate | 2021 |
| Garnant House LLP | | 2009 |
| Garnant Park Members Golf Club | Arts & recreation | 2014 |