| North West Floor Coverings Ltd | Construction | 2026 |
| ON Site Safety Solutions Limited | Hospitality | 2005 |
| Oriel Amlwch CIC | Wholesale & retail | 2025 |
| OS Logistics Ltd | Transport & logistics | 2024 |
| Owen Joinery Services Limited | Construction | 2022 |
| Parys Mountain Heritage Limited | Mining & quarrying | 2006 |
| Parys Mountain Land Limited | Mining & quarrying | 2006 |
| Paul Bargh Wealth Management Ltd | Financial services | 2013 |
| Pennant Pilotage Services Ltd. | Transport & logistics | 2018 |
| Penybont Properties Ltd | Construction | 2018 |
| Penybont Services Ltd | Construction | 2018 |
| Penymynydd Barns Management Ltd | Real estate | 2023 |
| Porfa Ltd | Agriculture & fishing | 2024 |
| RBH Aviation Ltd | Manufacturing | 2018 |
| Redkite Advanced Solutions Limited | Information & communication | 2015 |
| Rejsellstech Ltd | Wholesale & retail | 2025 |
| Rhodri Roberts Building Contractor Ltd | Construction | 2022 |
| Richard Owen Site Services Limited | Construction | 2018 |
| Rosewood Consulting Limited | Professional & scientific | 1998 |
| Safe Practice UK Consultancy Ltd | Professional & scientific | 2024 |
| Seaside Harmony Ltd | Health & social care | 2024 |
| Seim Holdings Ltd | Hospitality | 2023 |
| Seren Clothing Ltd | Wholesale & retail | 2024 |
| Shadowplay Design & Production Limited | Information & communication | 2013 |
| Shawcroft Supplies Ltd | Wholesale & retail | 2025 |
| Skye's Crepes Ltd | Hospitality | 2025 |
| Smart-Tech Kent Ltd | Wholesale & retail | 2006 |
| Solar Pen-Helm CYF | Energy | 2015 |
| Sonic Driver Limited | Manufacturing | 2017 |
| SRG Radsafe Limited | Professional & scientific | 2017 |
| Sticks and FUN Ltd | Education | 2018 |
| Support Sales Limited | Professional & scientific | 2019 |
| Synergy Fitness Hub Ltd | Health & social care | 2025 |
| T.E.Owen Ltd | Professional & scientific | 2022 |
| TAC Engineering Ltd | Manufacturing | 2022 |
| Techflite Ltd | Professional & scientific | 2022 |
| THE Financial Fairy Ltd | Professional & scientific | 2024 |
| THE Physio & Pilates Centre Ltd | Other services | 2001 |
| Themakeitcompany Ltd | Administrative & support | 2022 |
| Trearddur Bay Caravan Park Limited | Hospitality | 2026 |
| Trem Y MOR Holidays Ltd | Hospitality | 2026 |
| TY Monez Ltd | Real estate | 2025 |
| Tyddyn MON | Health & social care | 1988 |
| Vendmax Ltd | Hospitality | 2025 |
| W J Owen & SON Ltd | Mining & quarrying | 2015 |
| Wing WO Ltd | Hospitality | 2022 |
| WV Services Limited | Administrative & support | 2017 |