| Darshsat Consulting Services Limited | Information & communication | 2023 |
| Datacap Ltd | Information & communication | 2015 |
| Datayarn Limited | Information & communication | 2017 |
| Datitude Limited | Information & communication | 2012 |
| Datka Construction Ltd | Construction | 2014 |
| Dave Scott Services Ltd | Administrative & support | 2016 |
| David & Roger Franklin Ltd | Manufacturing | 2003 |
| Davoro Limited | Information & communication | 2018 |
| Davy Associates Limited | Professional & scientific | 2008 |
| DAW & Humble Homes Ltd | Real estate | 2024 |
| Dawfx Limited | Professional & scientific | 2024 |
| Dawn IT Solutions Ltd | Information & communication | 2018 |
| DB Interior Studio Ltd | Professional & scientific | 2015 |
| Dbear Exhibitions Limited | Administrative & support | 2021 |
| DBP Elite Holdco Limited | Financial services | 2020 |
| DBP Prime Holdco Limited | Financial services | 2020 |
| DCK Group Enterprises Ltd | Real estate | 2018 |
| DCL Safety Limited | Construction | 2012 |
| DCZ Ltd | Health & social care | 2019 |
| DE Havilland Chambers Limited | Administrative & support | 2014 |
| DE Rigo (UK) Limited | Wholesale & retail | 1995 |
| Deaconhall Consulting Limited | Professional & scientific | 2009 |
| Dean Tanner Commercial Flooring Ltd | Wholesale & retail | 2016 |
| Dearnside Motor Company Limited (the) | Wholesale & retail | 1971 |
| DED GUD Limited | Extraterritorial | 2024 |
| Deepa Bliss Ltd | Health & social care | 2025 |
| Deeya's Spices Ltd. | Manufacturing | 2022 |
| Delbury Management Company Limited | Households | 1994 |
| Dellwoods Ltd | Construction | 2025 |
| Denham Woodlands Nursery School Ltd | Education | 2012 |
| Dense & Pika Ltd | Arts & recreation | 2014 |
| Dental W12 Limited | Health & social care | 2020 |
| Denyer Developments Ltd | Construction | 2016 |
| Design and Making Ltd | Manufacturing | 2018 |
| Design Masters (Sales) Limited | Wholesale & retail | 1997 |
| Designing With Plants Ltd | Administrative & support | 2017 |
| Designs by Clarole Ltd | Wholesale & retail | 2022 |
| Desk Screens Ltd | Wholesale & retail | 1999 |
| Devbotics Solutions Ltd | Information & communication | 2025 |
| Devd Construction Co Ltd | Construction | 2025 |
| Devonshire Close Residents (Amersham) Limited | Households | 1970 |
| DG Project Management Associates Limited | Professional & scientific | 2014 |
| Dhyana Consultancy Ltd | Professional & scientific | 2015 |
| Dhyana International Ltd | Wholesale & retail | 2015 |
| Diamond Court Management Ltd | Real estate | 2015 |
| Dica Property Ltd | Real estate | 2023 |
| Dicebox Properties Limited | Real estate | 2020 |
| Didcot Land Limited | Construction | 2020 |
| Digidynamics Solutions Limited | Information & communication | 2024 |
| Digital Data Dynamics Limited | Information & communication | 2017 |
| Digital Gyan Limited | Professional & scientific | 2022 |
| Digital Pacex Ltd | Information & communication | 2021 |
| Diligenix Solutions Limited | Professional & scientific | 2024 |
| Diligent One Tech Ltd | Information & communication | 2024 |
| Dimaheap Ltd | Wholesale & retail | 2007 |
| Dion Partners Ltd | Administrative & support | 2025 |
| Direct Sight (UK) Ltd | Wholesale & retail | 2020 |
| Dirty Dog Groomers Ltd | Arts & recreation | 2024 |
| Diti Tech Ltd. | Information & communication | 2012 |
| Divine Proprietors Ltd | Other services | 2024 |
| Divsoft Limited | Information & communication | 2015 |
| Diwc Ltd | Wholesale & retail | 2025 |
| Djbgassafety.Co.Uk Ltd | Construction | 2026 |
| DMK IT Recruitment Ltd | Administrative & support | 2025 |
| DMP Property Solutions Ltd | Real estate | 2020 |
| Dmwb Consulting Limited | Professional & scientific | 2025 |
| DNA Auto Shipping Ltd | Wholesale & retail | 2025 |
| Doggy Dell Limited | Hospitality | 2022 |
| Dolly's Hair & Nail Salon Ltd | Other services | 2019 |
| DOM Design Ltd | Professional & scientific | 2013 |
| Donna Bella Ltd | Other services | 2013 |
| Doon Holdings Limited | Real estate | 2022 |
| Dorbrey Ltd | Real estate | 2021 |
| Doug Crowe Haulage Ltd | Transport & logistics | 2019 |
| Dove DEVELOPMENTS1 Ltd | Construction | 2022 |
| Dove Equestrian LLP | | 2024 |
| Dove Property Holdings Ltd | Real estate | 2022 |
| Dove Retail Ltd | Wholesale & retail | 2018 |
| Doveton Limited | Professional & scientific | 1979 |
| Downlands Apartments Management Company Limited | Households | 2006 |
| DP & AP Ltd | Wholesale & retail | 2023 |
| DP Property Services Ltd | Administrative & support | 2020 |
| DPA Sports Travel Ltd | Administrative & support | 2014 |
| DPA Sports Worldwide Limited | Administrative & support | 2017 |
| DR Challoner's Grammar School | Education | 2010 |
| DR Challoner's High School | Education | 2011 |
| DR Harmony Aesthetics Ltd | Health & social care | 2019 |
| DR IT Consulting Limited | Administrative & support | 2011 |
| Draen Ltd | Hospitality | 2024 |
| Draintec UK Limited | Construction | 2014 |
| Drarc Limited | Health & social care | 2023 |
| Dream Chase Ltd | Information & communication | 2021 |
| Dreamlease Ltd | Administrative & support | 2014 |
| Drink Japan Ltd | Administrative & support | 2022 |
| Drishi News Ltd | Wholesale & retail | 2017 |
| Driton Ltd | Other services | 2011 |
| Drop-Ship Packaging Ltd | Administrative & support | 2022 |
| DRS Finance Ltd | Professional & scientific | 2011 |
| DRW Capital Limited | Financial services | 2025 |
| Dtcrs Limited | Professional & scientific | 2011 |