| Dogfish Consultants Ltd | Information & communication | 2021 |
| Dollar Point Ltd | Wholesale & retail | 2017 |
| Dollar Tech Co. Ltd | Information & communication | 2025 |
| DOM Jones Composer Limited | Arts & recreation | 2024 |
| Domestic Doggess Limited | Other services | 2019 |
| Dominion Europe Limited | Administrative & support | 2020 |
| Dominion Financial Management Limited | Administrative & support | 2015 |
| Domino First Management Company Limited | Households | 1982 |
| Domino Second Management Company Limited | Households | 1982 |
| Donald Groups Limited | Health & social care | 2019 |
| Donnington Health Care Limited | Real estate | 2012 |
| Donya Consultancy Services Limited | Professional & scientific | 2007 |
| Doon Villa Holdings Limited | Real estate | 2018 |
| Door World Limited | Manufacturing | 1989 |
| Doorstep Deliveries Ltd | Transport & logistics | 2025 |
| Dopamin UK Ltd | Information & communication | 2024 |
| Dopple Limited | Financial services | 2023 |
| Dorchester Court Management Company (Sale) Limited | Households | 1973 |
| Dordon SPV Limited | Real estate | 2016 |
| Dorien Property Ltd | Real estate | 2013 |
| Dorsal FIN Procurement Limited | Professional & scientific | 2026 |
| Dorset Cottage Holidays Limited | Extraterritorial | 2011 |
| DOT Homewares Ltd | Wholesale & retail | 2020 |
| DOT Logics Limited | Information & communication | 2022 |
| DOT Store Digital Brands Ltd | Wholesale & retail | 2025 |
| Dotlance Limited | Administrative & support | 2009 |
| Double Eagle Pictures Ltd | Information & communication | 2024 |
| Double O66 Limited | Professional & scientific | 2025 |
| Doublecape Holding Limited | Professional & scientific | 1991 |
| Doublecape Limited | Professional & scientific | 1988 |
| Douglas Gillespie (Holdings) Limited | Professional & scientific | 2015 |
| Dovydas Ltd | Health & social care | 2019 |
| Down House Dental Practice Limited | Health & social care | 2010 |
| Downham Isle Brewery Ltd | Manufacturing | 2020 |
| Downloaddocs Limited | Administrative & support | 2010 |
| Downs Nominees Limited | Professional & scientific | 1995 |
| Downtown Asset Management Limited | Real estate | 2018 |
| Downtown Manchester BTR Ltd | Construction | 2023 |
| Downtown Manchester Jvco Ltd | Construction | 2023 |
| Downtown Manchester Jvco Phase 2 Limited | Construction | 2024 |
| Downtown Manchester Opco Limited | Real estate | 2023 |
| Downtown Manchester Propco Limited | Real estate | 2023 |
| Downtown Salford Limited | Real estate | 2014 |
| Downtown Salford Management Company Limited | Real estate | 2019 |
| Doyle Plastering Ltd | Construction | 2022 |
| DP Shark Limited | Professional & scientific | 2025 |
| DPH DM Limited | Professional & scientific | 2025 |
| Dpjm Hospitality & Events Ltd | Hospitality | 2025 |
| Dprp Limited | Health & social care | 2014 |
| DR 4 IT Consulting Limited | Information & communication | 2024 |
| DR a Gallacher Ltd | Health & social care | 2021 |
| DR Aiza Dermaspa Limited | Health & social care | 2026 |
| DR Amiry Gynaecology Ltd | Health & social care | 2023 |
| DR B Hulme Limited | Health & social care | 2013 |
| DR Caroline Warden Skin & Aesthetic Clinic Limited | Health & social care | 2026 |
| DR E Aesthetics Ltd | Health & social care | 2021 |
| DR Electronics Ltd | Construction | 2016 |
| DR Gorman Limited | Professional & scientific | 2021 |
| DR Hadia Wahaj Limited | Health & social care | 2015 |
| DR J S Deogan Ltd | Health & social care | 2022 |
| DR Jemma Stones Ltd | Health & social care | 2024 |
| DR Jennifer Anne Aesthetics Limited | Other services | 2019 |
| DR Jhetam Limited | Administrative & support | 2013 |
| DR Jonny Stevens Coaching Ltd | Education | 2026 |
| DR Jonny Stevens Group Ltd | Financial services | 2025 |
| DR Jonny Stevens Limited | Health & social care | 2021 |
| DR Jonny Stevens Property Ltd | Real estate | 2026 |
| DR Kate Jones Mrcvs Limited | Administrative & support | 2015 |
| DR KK Smiles Limited | Health & social care | 2025 |
| DR Koss Ltd | Health & social care | 2019 |
| DR M Talibi Ltd | Health & social care | 2025 |
| DR Olivia Spicer Ltd | Health & social care | 2025 |
| DR Preeti Shah Skin Aesthetics Ltd | Health & social care | 2017 |
| DR Saqib Chowdhary Limited | Health & social care | 2017 |
| DR Shilpa Aesthetics Ltd | Health & social care | 2020 |
| DR T & a Khan Limited | Health & social care | 2015 |
| DR Yasir Abbasi Limited | Health & social care | 2015 |
| DR. Alexander James Limited | Health & social care | 2018 |
| DR. Jonny Stevens Dental Limited | Health & social care | 2026 |
| DR. Raghda Ltd | Health & social care | 2025 |
| DR. Rajvir Dutt Ltd | Health & social care | 2021 |
| DR. U Narendran Limited | Health & social care | 2012 |
| Draffan Advisory Services Limited | Administrative & support | 2010 |
| Dragon Sportswear Limited | Manufacturing | 2014 |
| Dragon Swimwear Limited | Manufacturing | 2012 |
| Dragonfly Care Services Ltd | Other services | 2025 |
| Dragonfly Music LLP | | 2024 |
| Dragonfly Psychology Limited | Health & social care | 2021 |
| Dragonmobility Ltd | Manufacturing | 2005 |
| Dragonpass International Ltd. | Administrative & support | 2013 |
| Drain Dollies Ltd | Wholesale & retail | 2015 |
| Dramir Limited | Health & social care | 2019 |
| Draper Weddings Ltd | Wholesale & retail | 2012 |
| Drayton Mill Court Limited | Households | 2002 |
| DRD Cooling Ltd | Construction | 2014 |
| Drdashtgard Ltd | Health & social care | 2021 |
| Dream Author Coaching Ltd | Education | 2019 |
| Dream Big Consulting Ltd | Education | 2016 |
| Dream Big Developments Limited | Construction | 2023 |
| Dream Cottages Limited | Extraterritorial | 1998 |