| Defence Assist Plus Ltd | Professional & scientific | 2012 |
| Del's Barbers Limited | Other services | 2017 |
| Delamere Financial Limited | Professional & scientific | 2025 |
| Delancey Union Ltd | Professional & scientific | 2026 |
| Delegno Limited | Construction | 2009 |
| Delestre Services Limited | Administrative & support | 2016 |
| Delgnaps Ltd | Information & communication | 2026 |
| Deliverent Management Ltd | Construction | 2020 |
| Delko Installations Limited | Construction | 2023 |
| Dellar Fold Management Company Limited | Real estate | 2006 |
| Delta Dncb Limited | Professional & scientific | 2026 |
| Deltadale Limited | Professional & scientific | 1986 |
| Deluxe Eyecare Ltd | Wholesale & retail | 2016 |
| Demandscience Holdings UK Limited | Financial services | 2011 |
| Demandscience UK Limited | Administrative & support | 2010 |
| Dementiative Ltd | Professional & scientific | 2018 |
| Demep Ltd | Professional & scientific | 2025 |
| Dempster Consulting Ltd | Professional & scientific | 2023 |
| Denbigh Solutions Limited | Administrative & support | 2021 |
| Denmark Street Limited | Real estate | 2024 |
| Denstone Properties Limited | Real estate | 1991 |
| Denta Care Cheshire Ltd | Health & social care | 2016 |
| Dentalmasters Ltd | Health & social care | 2013 |
| Denton Court Flat Management Limited | Households | 1995 |
| Denton West END Primary School | Education | 2012 |
| Dentrazvi Ltd | Health & social care | 2021 |
| Denyer Limited | Administrative & support | 2006 |
| Deploy-It Project Solutions Limited | Professional & scientific | 2024 |
| Derivatives Clearing Technology Consulting Limited | Professional & scientific | 2024 |
| Dermaglow Limited | Other services | 2019 |
| Dermanude Academy Limited | Education | 2024 |
| Dermanude Limited | Other services | 2019 |
| Dermanude Online Limited | Wholesale & retail | 2024 |
| Dermawise Limited | Health & social care | 2023 |
| Dermex Limited | Construction | 2011 |
| Derra.Ai Limited | Information & communication | 2025 |
| Derwent Development Management Limited | Construction | 2020 |
| Derwent Estates Limited | Real estate | 1997 |
| Derwent River Research Limited | Professional & scientific | 2023 |
| Desai Optical Services Ltd | Health & social care | 2012 |
| Desi Stylz Ltd | Hospitality | 2019 |
| Design for Less Limited | Wholesale & retail | 2011 |
| Design Right Limited | Professional & scientific | 2010 |
| Design Your Lifestyle (Altrincham) Ltd | Wholesale & retail | 2024 |
| Designed Storage and Partitions Ltd | Construction | 2011 |
| Designer MEN Limited | Wholesale & retail | 2019 |
| Designs by ZOE Limited | Wholesale & retail | 2024 |
| Designview Projects Limited | Other services | 2025 |
| Desired Outcome Consulting Limited | Professional & scientific | 2015 |
| Destiny Advisory Ltd | Information & communication | 2025 |
| Destra Windmill Ltd | Extraterritorial | 2019 |
| Detail 2 Recruitment (Holdings) Limited | Financial services | 2018 |
| Detail 2 Recruitment (Manufacturing & Engineering) Limited | Administrative & support | 2021 |
| DETAIL2 Limited | Professional & scientific | 2026 |
| Detect & Protect Limited | Professional & scientific | 2024 |
| Determinist Ltd | Information & communication | 2023 |
| DEV March Limited | Information & communication | 2019 |
| Devasena Ltd | Health & social care | 2009 |
| Development by Design, UK Ltd | Professional & scientific | 2000 |
| Development Processes Group Limited | Education | 1992 |
| Devijeka Limited | Real estate | 2023 |
| Devik Consulting Limited | Information & communication | 2010 |
| Devils Heart Ltd | Wholesale & retail | 2024 |
| Devisdale Grange Residents Association Limited | Households | 1994 |
| Devitt Limited | Professional & scientific | 2020 |
| Devon and Cornwall Logistics Limited | Extraterritorial | 2024 |
| Devonshire Cottage Holidays Limited | Extraterritorial | 2009 |
| Devonshire Court (Sale) Management Company Limited | Households | 2003 |
| Devonshire Tower Ltd | Households | 2013 |
| Devops Info Ltd | Information & communication | 2018 |
| Devotion Accounting Limited | Professional & scientific | 2024 |
| Devotus Developments Ltd | Construction | 2025 |
| Devsai Properties Ltd | Real estate | 2020 |
| Dexter Wyatt Consultants Limited | Administrative & support | 2021 |
| Dexwhim Consulting Limited | Professional & scientific | 2022 |
| Dfgcc Padel Ltd | Arts & recreation | 2024 |
| DG Multibao Limited | Wholesale & retail | 2019 |
| DG Properties London Limited | Real estate | 2015 |
| DG Services (Altrincham) Limited | Administrative & support | 2000 |
| Dgapps Limited | Information & communication | 2023 |
| DGC Engineering Services Ltd | Professional & scientific | 2023 |
| Dgoi Limited | Professional & scientific | 2013 |
| DGR Business Consultancy Ltd | Professional & scientific | 2010 |
| DGT Legal Ltd | Professional & scientific | 2024 |
| DH Electrical (Cheshire) Limited | Construction | 2010 |
| DH Real Estate Consultants Ltd | Other services | 2020 |
| Dhan-Sukh Ltd | Real estate | 2021 |
| Dhap Corporate Trustee Limited | Extraterritorial | 2013 |
| Dhap Ltd | Extraterritorial | 2013 |
| DHF Accounting Limited | Professional & scientific | 2002 |
| Dhriti Solutions Limited | Administrative & support | 2025 |
| DIA Future UK Limited | Wholesale & retail | 2008 |
| Diabeat&Co Ltd | Wholesale & retail | 2024 |
| Diadem Jewellery Limited | Wholesale & retail | 2013 |
| Diagnostic & Rehab Services Limited | Health & social care | 2012 |
| Dial a Handyman North West Limited | Administrative & support | 2009 |
| Dial Spark Ltd | Information & communication | 2026 |
| Diamond Analytical Solutions Limited | Information & communication | 2023 |
| Diamond Data Solutions Limited | Information & communication | 2014 |
| Diamond Inscriptions Ltd | Information & communication | 2018 |