| Denning Legal Services Limited | Other services | 2019 |
| Dennis Taylor Limited | Arts & recreation | 2011 |
| Dentures 4 U Limited | Health & social care | 2022 |
| Derbyshire Gritstone Sheep Breeders Society Limited | Agriculture & fishing | 2005 |
| Designs by Inaya Ltd | Wholesale & retail | 2024 |
| Dessert Palace (Lanc) Ltd | Administrative & support | 2024 |
| Deutschewerks Limited | Wholesale & retail | 2014 |
| Devenish & Co (Weymouth) Limited | Manufacturing | 2015 |
| Devereux Accountants Limited | Professional & scientific | 2008 |
| Devers Building Services Ltd | Construction | 2024 |
| Devine Fisheries & Retreat Ltd | Agriculture & fishing | 2021 |
| Devine Fisheries Ltd | Agriculture & fishing | 2021 |
| Devine Hive Ltd | Agriculture & fishing | 2025 |
| Devine Retreat Ltd | Wholesale & retail | 2021 |
| Dexi Ltd | Administrative & support | 2017 |
| DFM Services Ltd | Construction | 2026 |
| DG Whitmoor Interiors Ltd | Construction | 2022 |
| DGW Contracting Ltd | Financial services | 2015 |
| Dhbrickwork Ltd | Construction | 2025 |
| Dhori Logistics Limited | Transport & logistics | 2019 |
| Diamond Paints Ltd | Manufacturing | 2025 |
| Diamondfilmproductionsuk Ltd | Information & communication | 2023 |
| Diesel Doctor Limited | Professional & scientific | 2026 |
| Digital Life Blueprint Ltd | Professional & scientific | 2017 |
| Diligent Lettings Ltd | Real estate | 2012 |
| Dill Hall Limited | Professional & scientific | 2013 |
| Dimension-Polyant (UK) Limited | Wholesale & retail | 1986 |
| Direct Clothing Supplies Ltd | Wholesale & retail | 2018 |
| Direct Cooling Systems Limited | Construction | 2000 |
| Direct Education and Training Limited | Arts & recreation | 2012 |
| Direct Sectional Buildings Limited | Manufacturing | 1998 |
| Discipline Sports Wear Limited | Wholesale & retail | 2024 |
| Discover Housing Ltd | Real estate | 2025 |
| Discovered Limited | Health & social care | 2017 |
| Discovery NW Ltd | Real estate | 2019 |
| Disruptive Film and Audio Productions Limited | Administrative & support | 2023 |
| Distinct Business Solutions Limited | Administrative & support | 2007 |
| Dixi World Limited | Hospitality | 2009 |
| Dixon Construction Management Limited | Construction | 2021 |
| Dixy Chicken Corporation Ltd | Hospitality | 2025 |
| DJR Nationwide Limited | Transport & logistics | 2013 |
| Dlicious Ltd | Wholesale & retail | 2018 |
| DLR Haulage Limited | Transport & logistics | 2017 |
| DM Stairs Ltd | Construction | 2025 |
| DMC Scaffolding Services Limited | Construction | 2015 |
| DNA I.T. Solutions Limited | Information & communication | 2005 |
| Dodge Nightclub Ltd | Hospitality | 2019 |
| Dome Electrical Project Solutions Ltd | Construction | 2023 |
| Dorset Media Group Limited | Professional & scientific | 2022 |
| Dovemills Ltd | Households | 2024 |
| DR Waste (North West) Limited | Water & waste | 2024 |
| Dragon Fire Group Limited | Construction | 2019 |
| Dream Kitchens and Bedrooms Ltd | Manufacturing | 2025 |
| Drewe Pattison Building Solutions Ltd | Construction | 2022 |
| Drink Sleep Inc Limited | Manufacturing | 2023 |
| Dryvn Ltd | Manufacturing | 2025 |
| DSLP18 Ltd | Extraterritorial | 2022 |
| DSLP23 Ltd | Extraterritorial | 2022 |
| DSLP24 Ltd | Extraterritorial | 2022 |
| DSLP25 Ltd | Extraterritorial | 2022 |
| DSLP26 Ltd | Extraterritorial | 2022 |
| DSLP27 Ltd | Extraterritorial | 2022 |
| DSLP28 Ltd | Extraterritorial | 2022 |
| DSLP29 Ltd | Extraterritorial | 2022 |
| DSLP30 Ltd | Extraterritorial | 2022 |
| DSLP32 Ltd | Extraterritorial | 2022 |
| DSLP34 Ltd | Extraterritorial | 2022 |
| DSLP35 Ltd | Extraterritorial | 2022 |
| DSLP36 Ltd | Extraterritorial | 2022 |
| DSLP37 Ltd | Extraterritorial | 2022 |
| DSLP38 Ltd | Extraterritorial | 2022 |
| DSLP39 Ltd | Extraterritorial | 2022 |
| DSLP40 Ltd | Extraterritorial | 2022 |
| DSLP80 Ltd | Extraterritorial | 2023 |
| DSLP81 Ltd | Extraterritorial | 2023 |
| DTJ Commercials Ltd | Wholesale & retail | 2022 |
| DTS Demand Creation Limited | Administrative & support | 2013 |
| Dube Inc Limited | Wholesale & retail | 2024 |
| Duggan Consultancy Limited | Construction | 2009 |
| DUO Legal Ltd | Professional & scientific | 2019 |
| Durasak Limited | Wholesale & retail | 1998 |
| Dursey Developments Limited | Construction | 2016 |
| Dursey Property Investments Limited | Real estate | 2020 |
| Dust N Cobwebs Limited | Other services | 2016 |
| DVH Property Developments Ltd | Construction | 2011 |
| Dynamic Design Holdings Ltd | Financial services | 2020 |
| Dynamic Design Services Ltd. | Professional & scientific | 2016 |
| E & M Brickwork Limited | Construction | 2019 |
| E Events International Ltd | Information & communication | 2019 |
| E Hydrogen Power Limited | Manufacturing | 2025 |
| E-Pui Co. Ltd | Real estate | 2021 |
| Eagle Cars Accrington Ltd | Transport & logistics | 2020 |
| Early Baird's Childrens Nursery Limited | Health & social care | 2013 |
| East Lancashire Motors Limited | Wholesale & retail | 2018 |
| East Lancs Holdings Limited | Financial services | 2024 |
| East Midlands Haulage Ltd | Transport & logistics | 2019 |
| Eastern Promise Accrington Ltd | Hospitality | 2026 |
| Easy Wash NW Ltd | Administrative & support | 2026 |
| Easypak NW Ltd | Wholesale & retail | 2023 |
| Eats by East Limited | Hospitality | 2024 |