| Pureblast Cleaning Solutions Ltd | Real estate | 2014 |
| Purity Plus Limited | Financial services | 2020 |
| Purple Computing Limited | Information & communication | 2010 |
| Purple Consultancy Group Ltd | Financial services | 2024 |
| Pushkat Solutions Ltd | Information & communication | 2018 |
| Putland-Shaw Limited | Professional & scientific | 2022 |
| PV Crystalox Solar PLC | Professional & scientific | 2006 |
| PW Electrics (Oxford) Limited | Construction | 2012 |
| PWD Athletic Academy CIC | Education | 2024 |
| PWD Care Limited | Health & social care | 2016 |
| PWM Carpentry Limited | Construction | 2026 |
| Pyrotec Holdings Limited | Financial services | 2007 |
| Pyrotec Services Limited | Wholesale & retail | 1979 |
| Q & Co Oxford Limited | Construction | 2010 |
| Q-Tech Global Limited | Manufacturing | 2023 |
| Qorus Limited | Professional & scientific | 2000 |
| Quagga Consulting Limited | Professional & scientific | 2020 |
| Quantum Electrical Solutions Ltd | Construction | 2016 |
| Quantum Prosthetics and Orthotics Limited | Extraterritorial | 1949 |
| Quarterman Investments Ltd | Real estate | 2022 |
| Quay Websites Ltd | Information & communication | 2015 |
| QUE Pasa Ltd | Hospitality | 2022 |
| Quecumbar Limited | Wholesale & retail | 2004 |
| Quest for Learning | Education | 2004 |
| Quickedivorce.Com Ltd | Extraterritorial | 2000 |
| Quiet Consensus Ltd | Information & communication | 2025 |
| Quod Associates Limited | Professional & scientific | 2014 |
| R & B Builders Ltd | Construction | 2007 |
| R Bridge Development Ltd | Manufacturing | 2019 |
| R C Logistics (U.K.) Limited | Transport & logistics | 1988 |
| R Harris Electrical Services Limited | Construction | 2020 |
| R J Mccartney & Sons Limited | Construction | 2007 |
| R Kingscote Limited | Arts & recreation | 2015 |
| R P S Group Limited | Administrative & support | 1987 |
| R&E Taverns Ltd | Hospitality | 2023 |
| R&L Associates Ltd | Professional & scientific | 2011 |
| R&S Quality Services Ltd | Administrative & support | 2022 |
| R. Woodford & Sons Limited | Arts & recreation | 2002 |
| R.G.B. Communications Limited | Administrative & support | 1991 |
| R.J.P. Motorcycles Limited | Wholesale & retail | 2014 |
| R.P. Cherry & SON Limited | Wholesale & retail | 1981 |
| Race Farm Management Company Limited | Real estate | 2006 |
| Rachael Anson ENT Ltd | Wholesale & retail | 2018 |
| Rachel Wallis Farming Limited | Agriculture & fishing | 2017 |
| Rachelbond Limited | Information & communication | 1981 |
| Radecol Consulting Limited | Professional & scientific | 2012 |
| Radical Jumps Limited | Information & communication | 2023 |
| Radley College Leisure Limited | Arts & recreation | 2009 |
| Radley College Services Limited | Construction | 1994 |
| Radley Schools Group Enterprises Limited | Education | 2025 |
| Radoslaw BAK Limited | Transport & logistics | 2024 |
| Rainbow Enterprises (London) Limited | Real estate | 2000 |
| Rainbow Raven Ltd | Transport & logistics | 2023 |
| Raleigh Park Clinic Limited | Health & social care | 2012 |
| Ramdntl Limited | Health & social care | 2024 |
| RAN Property Management Limited | Real estate | 2024 |
| RAN Wealth Management Ltd | Financial services | 2021 |
| Ranking Surge Ltd | Information & communication | 2024 |
| Rannieston Capital Limited | Real estate | 2025 |
| RAP Assets Limited | Financial services | 2024 |
| Rational Design Tools Ltd | Information & communication | 2023 |
| Ravopa Ltd | Wholesale & retail | 2026 |
| Raymond Thames Ltd | Real estate | 2025 |
| Razom CIC | Administrative & support | 2025 |
| RB LG LLP | | 2019 |
| RB Locksmiths Ltd | Professional & scientific | 2023 |
| RCM RENT2RENT Ltd | Real estate | 2025 |
| RCW Productions Ltd | Arts & recreation | 2006 |
| Re-Vamp Multiserve Limited | Other services | 2008 |
| Re:Pod Limited | Wholesale & retail | 2025 |
| Real Good Time Limited | Arts & recreation | 2015 |
| Rebecca Grove Ltd | Real estate | 2005 |
| Reborn Advisory Ltd | Other services | 2025 |
| Recraft Limited | Professional & scientific | 2016 |
| Rectory Healthcare Ltd | Health & social care | 2016 |
| Red Dragon Home Improvements Ltd | Construction | 2021 |
| Red Kite Close Limited | Administrative & support | 2019 |
| Red Kite Digital Accessibility Ltd | Information & communication | 2019 |
| Red Kite Management Consulting Limited | Professional & scientific | 2011 |
| Red Raft Films Ltd | Information & communication | 2025 |
| Red Train IT Limited | Information & communication | 2014 |
| Redkey Swift Digital Ltd | Wholesale & retail | 2024 |
| Redpepper Solutions Limited | Administrative & support | 2002 |
| Redspeed Rider Ltd | Transport & logistics | 2022 |
| Redy Maintenance Solution Ltd | Other services | 2024 |
| Reebick Developments Ltd | Other services | 2026 |
| Reebick Group Ltd | Other services | 2025 |
| Reed Financial Limited | Administrative & support | 2008 |
| Refined Homes and Gardens Ltd | Households | 2024 |
| Refract Speech Ltd | Information & communication | 2006 |
| Refsplaining Ltd | Information & communication | 2025 |
| Regent LCS Limited | Professional & scientific | 2021 |
| Rehabilitation and Performance Solutions Ltd | Health & social care | 2010 |
| Reid Talent Group Limited | Professional & scientific | 2014 |
| Rejoice Dental Care Limited | Health & social care | 2023 |
| Remy's Construction Ltd | Construction | 2014 |
| Renoma Ltd | Wholesale & retail | 2022 |
| Reox Investment Group Ltd | Real estate | 2025 |
| Replimune Limited | Professional & scientific | 2015 |
| Research Publishing International Ltd | Information & communication | 2016 |