| Emilia Jean Care Limited | Sheffield | 2020 |
| Emilia Popescu Ltd | Bury St. Edmunds | 2016 |
| Emin Steps Ltd | Bedford | 2025 |
| EMM Swale Ltd | Bourne | 2025 |
| Emmachris Ltd | Oldbury | 2023 |
| Emmanuel Humanity Foundation | London | 2021 |
| Emmerson-Ward TM Ltd | Doncaster | 2025 |
| EMP MAX Academy Ltd | London | 2022 |
| Empactus Limited | Cardiff | 2025 |
| Empet Group Ltd | London | 2026 |
| Empire Fire and Safety Limited | Retford | 2006 |
| Empire Fire Protection Ltd | Haverhill | 2025 |
| Empire Solutions Fire and Security Ltd | Maidstone | 2020 |
| Empire Square Limited | London | 2023 |
| Empirical Fire Safety Ltd | Edgware | 2023 |
| Emplace Associates Limited | London | 2023 |
| Empower and Evolve Limited | Peterborough | 2017 |
| Empower and Ignite CIC | London | 2025 |
| Empower HER Ethiopia Limited | London | 2026 |
| Empower Menopause Ltd | Wakefield | 2025 |
| Empower Send Consultancy Ltd | London | 2025 |
| Empowered Livin Ltd | Enfield | 2025 |
| Empoweredoasiscaregroup Ltd | Portsmouth | 2026 |
| Empowering Children's Care Ltd | Manchester | 2025 |
| Empowering Independence Limited | Mansfield | 2021 |
| Empowering Together CIC | Oldham | 2025 |
| Empsn Infrastructure Limited | Northampton | 2012 |
| Empsn Services Limited | Northampton | 2006 |
| Empyrean Fire Consultancy Ltd | Taunton | 2026 |
| Emtrades Limited | Wokingham | 2025 |
| Emzenith Limited | Leatherhead | 2024 |
| EN Bossa Ltd | Brentwood | 2025 |
| Enable Support Limited | Derby | 2019 |
| Enabled Consulting Ltd | Northampton | 2025 |
| Enableelite CIC | Birmingham | 2024 |
| Encompass Care Organisation UK | Dorchester | 1990 |
| Endo & Beyond Ltd | Wembley | 2025 |
| Endo Academy Limited | London | 2014 |
| Endoiiment Community CIC | London | 2025 |
| Endurance Care Services Limited | Rochester | 2022 |
| Endurance Health Care Limited | London | 2019 |
| Enerst Care Ltd | Manchester | 2019 |
| Enfermeria DE Atencion Primaria Ltd | London | 2025 |
| Enforcement Group Ltd | Manchester | 2023 |
| Engage S.W. Ltd | Shepton Mallet | 2014 |
| Engage Technical Solutions Ltd | Chippenham | 2011 |
| Engaged Workforce Solutions Ltd | London | 2024 |
| Engineered Life by Design Ltd | Milton Keynes | 2025 |
| England Mexdel Social Limited | Manchester | 2026 |
| Engterprises Ltd | London | 2017 |
| Enhance Fire Service Ltd | Cardiff | 2025 |
| Enhanced Care and Support Services Ltd | Manchester | 2026 |
| Enhanced Health and Beauty by Vera Ltd | London | 2022 |
| Enhanced Pharm Services and Aesthetics Limited | Derby | 2023 |
| Enhancing Independence Care Limited | Chatham | 2024 |
| Enipeter Limited | Leicester | 2020 |
| Ennovat Care Ltd | Harlow, Essex, | 2024 |
| Enriching Lives CIC | London | 2026 |
| Ensure Safety and Training Limited | Nantwich | 2013 |
| Enterprise Fire Security Limited | London | 2025 |
| Enterprising Transition Care Ayrshire C.I.C. | Kilmarnock | 2022 |
| Entertainment Media Limited | Newcastle Upon Tyne | 2019 |
| Entrust Fire Ltd | Coventry | 2019 |
| ENV Technology Insulation and Fire Ltd | Crook | 2021 |
| Envic Plus Limited | Orpington | 2018 |
| Envirofin Limited | Tamworth | 2021 |
| Environmental Markets Board Limited | Milton Keynes | 2026 |
| Envision VA Services Limited | Weymouth | 2023 |
| Envoy Care Ltd | Sutton-In-Ashfield | 2019 |
| Enztoke Limited | Bromley | 2024 |
| EOS Safety Limited | Darlington | 2025 |
| Epacuk Community Interest Company | Birmingham | 2024 |
| EPC Energyx Ltd | Derby | 2023 |
| EPD Fire Solutions Ltd | Herne Bay | 2025 |
| EPE Trusted to Protect (UK) Limited | Birmingham | 2026 |
| Ephratah Services Ltd | Wokingham | 2018 |
| Epicare Young People Services Ltd | London | 2025 |
| Epione Integrated Psychotherapy Ltd | Pershore | 2026 |
| Epitome Home Care Ltd | Edinburgh | 2023 |
| Epsom Ltd | London | 2025 |
| Equality Care Ltd | Nottingham | 2025 |
| Equicare Assess Ltd | Leeds | 2025 |
| Equiconfidence Limited | East Boldon | 2026 |
| Equilivra Ltd | Colchester | 2025 |
| Equisent Ltd | Newry | 2025 |
| ERA Services C.I.C. | London | 2020 |
| Erco Solutions Limited | Northampton | 2020 |
| Erebus UK Ltd | Hereford | 2008 |
| Eren Healthy Life Consultancy Ltd | London | 2021 |
| Erfolg Financial Regulatory Consulting Ltd | Ashford | 2019 |
| Erif (UK) Limited | London | 2015 |
| Erifire Safety Ltd | St. Neots | 2024 |
| ERIKSON68LTD Limited | Manchester | 2025 |
| Erimus Safety Ltd | Middlesbrough | 2023 |
| Erina Healthcare Ltd | Coventry | 2023 |
| Eritrea GIE Limited | London | 2025 |
| ERK Care Limited | Colchester | 2023 |
| Ermco Limited | Crawley | 2021 |
| Eroberto Ltd | Ashford | 2023 |
| Errington Springall Defence Limited | Warwick | 2024 |