| Big City Print Ltd | Nottingham | 2011 |
| Big Coffee Brands Ltd | Redhill | 2025 |
| Big Crust Ltd | Aberdeen | 2026 |
| Big Cube Club Ltd | Enfield | 2019 |
| Big Daddy Manufacturing Limited | London | 2018 |
| Big Daddy Prints Ltd | Hounslow | 2018 |
| Big DAL Ltd | London | 2026 |
| Big Dawg Media Limited | East Kilbride | 2022 |
| Big Deal Investments Limited | Leeds | 2013 |
| Big Deez Ltd | Cardiff | 2017 |
| Big Design and Print Ltd | Eynsham | 2023 |
| Big DIG Brewhouse Ltd | Winterborne Kingston | 2025 |
| Big Dinger's Ltd | Kington | 2026 |
| Big Dog Bakery Ltd | Wakefield | 2018 |
| Big Dog BED Company Ltd | Henley-On-Thames | 2011 |
| Big Dog Van Accessories Limited | Tonypandy | 2025 |
| Big Drop Brewing Company Limited | Ipswich | 2016 |
| Big Easy Printing Ltd | Melton Mowbray | 2021 |
| Big ECK Limited | Luton | 2022 |
| Big Excel Ltd | London | 2022 |
| Big FAT Slab Ltd | Birmingham | 2017 |
| Big Feature Prints Ltd | London | 2018 |
| Big Fella Brewing Ltd | London | 2026 |
| Big Ferro Limited | London | 2015 |
| Big Ferro Trading Ltd | London | 2023 |
| Big Fish Consulting Limited | Cardiff | 2014 |
| Big Fish SRL Limited | Horsmonden | 2014 |
| Big Fish Welding Ltd | Irlam | 2015 |
| Big Fit Nutrition Ltd | Liverpool | 2019 |
| Big Foot Catering Limited | Bangor | 1993 |
| Big Foot Kitchens Ltd | Stourbridge | 2023 |
| Big FUN Bikes Ltd | London | 2017 |
| Big FUN UK Limited | Dartford | 2017 |
| Big Game Hunters Limited | Abingdon | 2020 |
| Big Gates Ltd | Ilford | 2025 |
| Big Gesture Limited | Leicester | 2017 |
| Big Gorilla Group Ltd | Shotton | 2026 |
| Big Gorilla Signs Limited | Hartlepool | 2014 |
| Big Green Box (UK) Limited | Grantham | 2008 |
| Big Halo Ltd | London | 2018 |
| Big Hand Brewing Company Limited | Nottingham | 2012 |
| Big Impact Group Limited | Hitchin | 2023 |
| Big J Food Concepts Limited | Nottingham | 2024 |
| Big Jim's Kitchen Ltd | Edinburgh | 2021 |
| Big John's Limited | London | 2019 |
| Big K Ltd | London | 2015 |
| Big K Products UK Limited | Mill Mead Road Tottenham Hale | 1981 |
| Big KID Industries Ltd | High Wycombe | 2021 |
| Big Kings Limited | London | 2015 |
| Big Lake Bait Boats Ltd | Holme | 2018 |
| Big Lens BAG Limited | Guildford | 2024 |
| Big Light Brewing Ltd | Livingston | 2023 |
| Big Light Entertainment Ltd | Wishaw | 2025 |
| Big Little Projects Ltd | London | 2025 |
| Big M Timber (Aberdeen) Limited | Aberdeen | 2023 |
| Big M Timber Products Limited | Aberdeen | 2005 |
| Big Machinery UK Ltd | Chiswick | 2021 |
| Big Macro Co., Ltd | Stockport | 2021 |
| Big MAN Group UK Limited | London | 2025 |
| Big Melt Ltd | Nottingham | 2017 |
| Big Message Media Ltd | Lytham St. Annes | 2014 |
| Big Metal Limited | | 1996 |
| Big Mick's Sauces Ltd | Kington | 2024 |
| Big Mommas Waffles Ltd | Manchester | 2015 |
| Big Momo Limited | London | 2024 |
| Big Monster Ltd | Altrincham | 2014 |
| Big Mountain Brewing Company Limited | London | 2017 |
| Big NOM Ltd | London | 2024 |
| Big O Enterprise Ltd | London | 2026 |
| Big on Bikes Limited | Derbyshire | 2003 |
| Big on Time Ltd | Birmingham | 2019 |
| Big Orange Solutions Ltd | Stoke-On-Trent | 2016 |
| Big P Sounds Ltd | Croydon | 2024 |
| Big Panda Holding Ltd | West Midlands, England | 2023 |
| Big Peat Sheet Metal Services Ltd | Cambridge | 2025 |
| Big Penny Ltd | London | 2009 |
| Big Point Limited | Willenhall | 2020 |
| Big Pole Ltd | Perth | 2018 |
| Big POT Co. Ltd | Cookstown | 2009 |
| Big Print Direct Ltd | Abergele | 2017 |
| Big Print Limited | Newbury | 2007 |
| Big Punch Studios Limited | Gloucester | 2015 |
| Big Purple Door Ltd | London | 1968 |
| Big Red Audio Ltd | Truro | 2018 |
| Big Red Kite Ltd | Swindon | 2002 |
| Big Red Rope Access Ltd | Barnsley | 2014 |
| Big Rude Food Ltd | Huddersfield | 2020 |
| Big Shop Friday Ltd | Milton Keynes | 2019 |
| Big Skies Brewing Company Ltd | Sleaford | 2025 |
| Big Smoke Brew Co Limited | Esher | 2014 |
| Big Spoon Brands Limited | Weybridge | 2020 |
| Big Square Limited | Belfast | 2023 |
| Big Star Glazing Ltd | Cambridgeshire | 2022 |
| Big Stick Engineering Ltd | London | 2026 |
| Big Strides Ltd | Birmingham | 2020 |
| Big Success Limited | London | 2019 |
| Big T (Tea) Limited | Wimborne | 2010 |
| Big Talk Consulting Ltd | Gravesend | 2022 |
| Big Texas Group Ltd | Birmingham | 2025 |
| Big Things Clothing Ltd | Clevedon | 2019 |