| Desktop Logic Limited | Sandy | 2011 |
| Desmond and Company Limited | Launceston | 2013 |
| Desmond De-Oliver Henry Ltd. | Oldbury | 2022 |
| Desmond Jackson Funeral Director Limited | Shipley | 2020 |
| Desmond Motors (Leasing) Limited | Co.Londonderry | 1978 |
| Desolenator UK Ltd | London | 2014 |
| Despatch Deadlines Limited | Buckinghamshire | 1997 |
| Desrick George Hesson Ltd | Wolverhampton | 2025 |
| Destination Holdings Ltd | Norwich | 2022 |
| Destination NET Zero Ltd | London | 2020 |
| Destination Party Limited | Musselburgh | 2013 |
| Destination Rainbow Ltd | Stourport-On-Severn | 2021 |
| Destination Weddings (UK) Ltd | Cardiff | 2012 |
| Destinator Ltd | London | 2026 |
| Destiny Calling Ltd | London | 2016 |
| Destiny Films Ltd | Small Dole | 2012 |
| Destiny Gaming Limited | Ely | 2020 |
| Destiny Investment Properties Ltd | Wallington | 2024 |
| Destiny Rich Ltd | Wetherby | 2024 |
| Destiny Scotch Whisky Company Limited | Leven | 2010 |
| Destra Windmill Ltd | Altrincham | 2019 |
| Destroy-It Destruction Services Limited | Bedford | 2018 |
| Destroy-It Limited | Bedford | 2018 |
| Detai Hair Limited | London | 2022 |
| Detail Cleaning Ltd | Chipping Norton | 2022 |
| Detail Design Engineering Limited | Sale | 1991 |
| Detailing Direct Limited | Braintree | 2008 |
| Detailworx Ltd | Reading | 2014 |
| Detec Security Limited | Burnley | 2007 |
| Detect Fire and Security Ltd | Lancashire | 2005 |
| Detectadye Limited | Newcastle | 2016 |
| Detegi Consulting Limited | Hartlepool | 2023 |
| Detension Biotechnology PTY. Ltd. | West Midlands, England, | 2014 |
| Deter Limited | Harrogate | 2012 |
| Detergent Information Limited | Manchester | 1978 |
| Determined to Thrive Ltd | Dartford | 2025 |
| Deterrent Security Systems Ltd | Wrexham | 2014 |
| Detian Corp Trading Limited | London | 2016 |
| Detm Limited | Bedlington | 2020 |
| Detour Films Limited | London | 2014 |
| Detox Sandwich Company Ltd | Coventry | 1999 |
| Dettling Developments Limited | Egham | 1998 |
| Deut ZAN Sefton Ltd | Abergele | 2026 |
| Deuteronomy 8 Ltd. | Glasgow | 2006 |
| Deutsch Executive Student Apartments Service | London | 2021 |
| Deutsche Collection Limited | London | 2019 |
| Deutsche Druckfarben UK Limited | Bournemouth | 2024 |
| Deutsche Viking Cargo Limited | London | 2022 |
| Deutschland Limited | Harrogate | 2022 |
| DEV Techblitz Ltd | St. Austell | 2025 |
| Deva Capital Limited | Bury | 2021 |
| Deva International Limited | Nottingham | 1991 |
| Deva Systems Limited | Bury | 2021 |
| Devadas Property Ltd | Harrow | 2022 |
| Devailytics Limited | Welwyn | 2025 |
| Devally Ltd | Lytham St. Annes | 2011 |
| Devanshi Ltd | Leicester | 2009 |
| Devault Limited | Bury | 2021 |
| Devdib Ltd | Cardiff | 2023 |
| Devdin Limited | Manchester | 2005 |
| Develop Global Partners Ltd | Bridge Of Allan | 2013 |
| Develop Global Training Ltd | London | 2019 |
| Develop Potential Limited | Swansea | 1999 |
| Develop Together Ltd | Norwich | 2024 |
| Developers Partners Limited | Thornton Heath | 2023 |
| Development 5 Kingsbridge CST Ltd | Birmingham | 2018 |
| Development Direct Global Partnerships | Stamfordham | 2009 |
| Development Finance Ltd. | Glasgow | 2009 |
| Development Restoration Modernisation Ltd | Knutsford | 2017 |
| Development Through Sports Limited | Caldicot | 2019 |
| Development UK 05 Limited | London | 2022 |
| Development UK 11 Limited | London | 2022 |
| Development UK 15 Limited | London | 2022 |
| Development UK 39 Limited | London | 2021 |
| Developments (Bromborough ) Limited | Rochdale | 2009 |
| Developmyplan Limited | Wimborne | 2013 |
| Devenish Manor Gatelodge's Ltd | Coleraine | 2006 |
| Dever Valley Produce Limited | Winchester | 2010 |
| Devereux Holdings Ltd | Daventry | 2024 |
| Devi (London) Properties Limited | Loughton | 2019 |
| Device Services Ltd | Stourbridge | 2025 |
| Devils Own Clothing Limited | Leicester | 2013 |
| Devils Own Tattoo and Piercing Studio Limited | Whetstone | 2001 |
| Devils PIT Limited | London | 2022 |
| Devimead BSA Limited | Aberystwyth | 1995 |
| Devimead Limited | Aberystwyth | 2012 |
| Devinder Grewal Limited | Slough | 2025 |
| Devinder Singh Grewal Limited | Slough | 2025 |
| Devine by Design Limited | Billericay | 2004 |
| Devine Management Services Ltd | Watford | 2008 |
| Devizes Cranes Limited | Devizes | 1994 |
| Devizes Hire Limited | Devizes | 2004 |
| Devizes Inn Limited | Salisbury | 2015 |
| Devizes Reclamation Company Limited | Devizes | 1984 |
| Devlin Glass Ltd | Magherafelt | 2009 |
| Devlon Holdings International Limited | London | 2020 |
| Devoc Ltd | Solihull | 2021 |
| Devon & Cornwall Boiler & Heating Spares Limited | Liskeard | 2005 |
| Devon & Exeter 2007 Limited | Glos | 2007 |
| Devon & Exeter Steeplechases | Glos | 1956 |