| Savonlinnan Kodintekniikka Oy | Wholesale & retail | 1993 |
| Savonlinnan Kuljetus Oy | Transport & logistics | 1970 |
| Savonlinnan Kuntoutus Ky | Health & social care | 1981 |
| Savonlinnan Kuormakuljetus Oy | Transport & logistics | 1995 |
| Savonlinnan Kuvakeskus Oy | Wholesale & retail | 1979 |
| Savonlinnan Lämpöpumppu Oy | Construction | 2008 |
| Savonlinnan Mainospalvelu Oy | Professional & scientific | 2016 |
| Savonlinnan Maisemaranta Oy | Hospitality | 1990 |
| Savonlinnan Mediat Oy | Information & communication | 2014 |
| Savonlinnan Mitta-Keittiöt Oy | Construction | 2001 |
| Savonlinnan Moniosa Oy | Wholesale & retail | 2015 |
| Savonlinnan Nikama Oy | Health & social care | 2018 |
| Savonlinnan OMT Fysioterapia Oy | Health & social care | 2009 |
| Savonlinnan Olutpanimo Oy | Manufacturing | 1993 |
| Savonlinnan Oopperajuhlat Oy | Arts & recreation | 1986 |
| Savonlinnan PR-Urakointi Oy | Construction | 2009 |
| Savonlinnan Rakennus- ja Peltityö Oy | Construction | 2009 |
| Savonlinnan Rakentajat Oy | Construction | 1980 |
| Savonlinnan Rengaspaja ja öljy T&J avoin yhtiö | Other services | 2006 |
| Savonlinnan Restateam avoin yhtiö | Professional & scientific | 1999 |
| Savonlinnan SLS-Kuljetus Oy | Transport & logistics | 2010 |
| Savonlinnan STR-Palvelu Avoin Yhtiö | Administrative & support | 2003 |
| Savonlinnan Sammutinhuolto Oy | Wholesale & retail | 2011 |
| Savonlinnan Saumakate Ky | Wholesale & retail | 1991 |
| Savonlinnan Savola 4 Oy | Manufacturing | 1999 |
| Savonlinnan Seudun Matkailu Oy | Administrative & support | 2010 |
| Savonlinnan Siivous- ja Kiinteistöhuoltokeskus Oy SK2 | Administrative & support | 2006 |
| Savonlinnan Soitinkulma Oy | Wholesale & retail | 1991 |
| Savonlinnan Sokerileipomo Oy | Manufacturing | 1993 |
| Savonlinnan Sydän Oy | Health & social care | 2014 |
| Savonlinnan Säde Oy | Other services | 2007 |
| Savonlinnan Terveyspalvelu Kommandiittiyhtiö Marja-Leena Kinnunen | Health & social care | 1976 |
| Savonlinnan Terähuolto Oy | Administrative & support | 1999 |
| Savonlinnan Teräs-, Eristys- ja Putkityö Oy | Construction | 1996 |
| Savonlinnan Tilitoimisto Oy | Professional & scientific | 1992 |
| Savonlinnan Tulostuspalvelu Oy | Administrative & support | 2023 |
| Savonlinnan Työterveys Oy | Health & social care | 2025 |
| Savonlinnan Ulataksi Oy | Transport & logistics | 1974 |
| Savonlinnan Urheilu Vepsäläinen Oy | Wholesale & retail | 1976 |
| Savonlinnan Varaosapalvelu Ky | Wholesale & retail | 1980 |
| Savonlinnan Vartiointikeskus Oy | Administrative & support | 2006 |
| Savonlinnan Vihannestukku Oy | Wholesale & retail | 2012 |
| Savonlinnan Vuokratalot Oy | Real estate | 1990 |
| Savonlinnan Yritystilat Oy | Real estate | 1987 |
| Savonlinnan linja-autoasema Oy | Real estate | 1979 |
| Savonlinnasali Oy | Arts & recreation | 2000 |
| Savonpirkka Infra Oy | Construction | 2019 |
| Savonpirkka Ky | Wholesale & retail | 1985 |
| Savontähti Oy | Construction | 2009 |
| Savorax Oy | Construction | 2007 |
| Savoteam Oy | Manufacturing | 2014 |
| Savotek Oy | Administrative & support | 2016 |
| Savotrim Oy | Other services | 2026 |
| Saxia Oy | Wholesale & retail | 1993 |
| Scandic Station Oy | Hospitality | 2023 |
| Scandomo Oy | Construction | 2012 |
| Scannova Oy | Health & social care | 2002 |
| SecWorks Oy | Wholesale & retail | 2020 |
| Selkäranta Ky | Manufacturing | 2010 |
| Setomet Oy | Construction | 1998 |
| Shadow Books Oy | Information & communication | 2023 |
| Shahi Ruoka Limited Oy | Hospitality | 2024 |
| Shokeen Oy | Hospitality | 2023 |
| SiPeRi Oy | Arts & recreation | 2021 |
| Sierra Technology and Business Solutions Oy | Professional & scientific | 2025 |
| Siivous-Info Oy | Wholesale & retail | 1993 |
| Siivousta Vaille Valmis Oy | Administrative & support | 2024 |
| Sijoitusyhtiö Hoff Oy | Financial services | 2005 |
| Silavuo Oy | Transport & logistics | 2018 |
| Silvennoinen & Falck Ky | Wholesale & retail | 1990 |
| Silver One Oy | Hospitality | 2019 |
| Simbi oy | Hospitality | 2024 |
| Simos Oy | Real estate | 2019 |
| Sioma Oy | Construction | 1997 |
| Sipsi Siivouspalvelu Oy | Administrative & support | 2022 |
| Sirkan Ravintolat Oy | Hospitality | 1973 |
| Sisustus Marenka ky | Wholesale & retail | 1991 |
| Sisustussuunnittelutoimisto Butterfly Ky | Professional & scientific | 2010 |
| Sivuraide Oy | Professional & scientific | 2024 |
| Smartix Oy | Other services | 2013 |
| Soitinmestari Nertia Oy | Professional & scientific | 2009 |
| Sonya Films Oy | Professional & scientific | 2024 |
| Sopanen Capital Oy | Financial services | 2024 |
| Sorvos Oy | Other services | 2005 |
| Sport Savonlinna Oy | Arts & recreation | 2013 |
| Starus Oy | Professional & scientific | 2023 |
| Statel Nordic Oy | Professional & scientific | 2008 |
| Steak-House San Martin Ky | | 1982 |
| Stellalane Oy | Professional & scientific | 2006 |
| Strong Sport Savonlinna Oy | Arts & recreation | 2017 |
| SubSavo Oy | Professional & scientific | 2012 |
| Sudensuu Oy | Administrative & support | 2004 |
| Sulkavan Betoni Oy | Manufacturing | 1986 |
| Sunvirta Oy | Construction | 2023 |
| Suomen Alfa- Cleaning Oy | Wholesale & retail | 1978 |
| Suomen Ammattivaruste Oy | Wholesale & retail | 2019 |
| Suomen Kattoasennus ja Huolto Oy | Construction | 1994 |
| Suomen Laatututkimus Oy | Professional & scientific | 2012 |
| Suomen Metsävara Oy | Agriculture & fishing | 1996 |
| Suomen Pintaehoste Oy | Construction | 2002 |