| 208MR. Blue Ltd | Wholesale & retail | 2025 |
| 20SCHEMES Ltd | Other services | 2023 |
| 20SCHEMESRETRAIN C.I.C. | Financial services | 2021 |
| 21 Edinburgh Ltd | Hospitality | 2016 |
| 211 Taxis Ltd | Professional & scientific | 2020 |
| 2112 Media & Sports Group LLP | | 2019 |
| 212 Properties Limited | Real estate | 2020 |
| 212ME Ltd | Information & communication | 2025 |
| 2159 Investment Company Limited | Other services | 2020 |
| 22 Bernard Street Ltd | Real estate | 2024 |
| 22 Nominees Limited | Other services | 1986 |
| 220 Taxis Ltd | Professional & scientific | 2016 |
| 2204 Holdings Limited | Financial services | 2022 |
| 222 South Street Limited | Real estate | 2017 |
| 225 Taxis Ltd. | Transport & logistics | 2008 |
| 227 Limited | Extraterritorial | 1998 |
| 22QS Limited | Real estate | 2023 |
| 24 ABC Limited | Manufacturing | 2025 |
| 24 ALL ABC Ltd | Construction | 2026 |
| 24 Craigour AVE Ltd | Construction | 2025 |
| 24 RT Limited | Hospitality | 2015 |
| 24 Trees Limited | Agriculture & fishing | 2024 |
| 24/7 Social Care Ltd | Health & social care | 2022 |
| 24601 Limited | Administrative & support | 2016 |
| 247 Emergency Plumbing Edinburgh Ltd | Construction | 2022 |
| 247 Group Facilities Ltd | Water & waste | 2025 |
| 247 Solutions Group LP | | 2015 |
| 2475 ST UK Limited | Other services | 2025 |
| 247CITYCAB&COURIERS Ltd | Transport & logistics | 2025 |
| 247EXECUTIVERYDES Limited | Transport & logistics | 2025 |
| 24A Holdings Limited | Wholesale & retail | 2021 |
| 25 RS Holdco Limited | Real estate | 2021 |
| 250 Edin Ltd. | Transport & logistics | 2004 |
| 253 Taxis Ltd | Professional & scientific | 2014 |
| 26 Dublin Street Limited | Construction | 2007 |
| 266 Taxis Ltd | Professional & scientific | 2017 |
| 268 Edin Ltd. | Transport & logistics | 2007 |
| 26GS (Trustees) Limited | Administrative & support | 2014 |
| 28 Industries Ltd | Manufacturing | 2026 |
| 282 Edin Ltd. | Other services | 2005 |
| 283 Taxis Ltd. | Professional & scientific | 2019 |
| 29 Business Solutions Ltd | Professional & scientific | 2023 |
| 291 Edin Ltd. | Professional & scientific | 2004 |
| 291 Media Limited | Professional & scientific | 2020 |
| 296 Edin Ltd. | Transport & logistics | 2006 |
| 299 Edin Ltd. | Other services | 2004 |
| 29A Holdings Limited | Financial services | 2023 |
| 29A Properties Limited | Real estate | 2024 |
| 29TWELVE Limited | Professional & scientific | 2020 |
| 2AM Digital Limited | Professional & scientific | 2026 |
| 2B Grange Court Ltd | Real estate | 2023 |
| 2B Technologies LP | | 2018 |
| 2BLIND2DRAW Ltd | Information & communication | 2017 |
| 2BROS Holdings Ltd | Hospitality | 2024 |
| 2EHPE LLP | | 2012 |
| 2EQ Limited | Professional & scientific | 2026 |
| 2GS Holding Ltd | Real estate | 2021 |
| 2H Holdings Limited | Real estate | 2019 |
| 2I Limited | Information & communication | 2005 |
| 2PAGES Limited | Information & communication | 2019 |
| 2PAYUBACK Limited | Information & communication | 2021 |
| 2PSP Limited | Manufacturing | 2025 |
| 2QQ Limited | Information & communication | 2019 |
| 2S Digitals LP | | 2015 |
| 2SI Consulting Limited | Information & communication | 2022 |
| 2SPICY Ltd | Wholesale & retail | 2011 |
| 2T Scaffolding Limited | Construction | 2012 |
| 2WB Limited | Professional & scientific | 2025 |
| 2Y Marketing LP | | 2014 |
| 2ZLF Ltd. | Water & waste | 2013 |
| 3 Alania Ltd | Hospitality | 2025 |
| 3 Bridges Capital Limited | Administrative & support | 2018 |
| 3 ED Glasgow Limited | Construction | 1998 |
| 3 ED Holdings 2 Limited | Professional & scientific | 2007 |
| 3 ED Holdings Limited | Construction | 1998 |
| 3 ED Sisterco Limited | Construction | 2007 |
| 3 Paddy's Limited | Hospitality | 2023 |
| 3 ST Andrew Square Apartments Limited | Construction | 1988 |
| 309 Honey UK Ltd | Wholesale & retail | 2026 |
| 31 Edin Ltd. | Professional & scientific | 2006 |
| 312 Accountancy Ltd | Professional & scientific | 2020 |
| 316 Scottaxis Limited | Extraterritorial | 2020 |
| 31ZAM ZAM Ltd | Wholesale & retail | 2025 |
| 321PASTA Ltd | Hospitality | 2022 |
| 323 Digital Works Ltd | Wholesale & retail | 2026 |
| 324 Scottaxis Limited | Extraterritorial | 2021 |
| 329 Edin Ltd. | Extraterritorial | 2004 |
| 331 Developments Ltd | Real estate | 2020 |
| 336 Financial Management Ltd | Financial services | 2011 |
| 339 Taxis Ltd | Professional & scientific | 2015 |
| 34 Melville Street Holdco Limited | Real estate | 2021 |
| 34 Melville Street Limited | Real estate | 2021 |
| 3553 Ltd | Health & social care | 2026 |
| 359 Group Ltd | Wholesale & retail | 2026 |
| 359 Media Limited | Wholesale & retail | 2024 |
| 35TVS Holdings Ltd | Financial services | 2025 |
| 360 Resilience Ltd | Information & communication | 2017 |
| 365 Day Store Ltd | Wholesale & retail | 2025 |
| 365 Global Consulting Ltd | Information & communication | 2013 |
| 36FIIVE Ltd | Other services | 2018 |