| Ellis Tech Solutions Ltd | Professional & scientific | 2026 |
| Ellisco Limited | Real estate | 2015 |
| ELM Hall Investments Ltd | Construction | 2021 |
| Elm-Performance Limited | Professional & scientific | 2015 |
| Elora Curations Ltd | Wholesale & retail | 2025 |
| ELS Plant LLP | | 2011 |
| ELS Plant Sales Limited | Wholesale & retail | 2023 |
| Elsa Property Investment Limited | Real estate | 2017 |
| Elsden Limited | Hospitality | 2019 |
| Elsim Consulting Ltd | Financial services | 2025 |
| EM Haulage Ltd | Transport & logistics | 2024 |
| EM Healthcare Limited | Health & social care | 2012 |
| Ember and Ivory Ltd | Hospitality | 2025 |
| Emberton Vines Ltd | Hospitality | 2022 |
| Embrace Housing CIC | Hospitality | 2020 |
| Eminence Grise Consulting Ltd | Professional & scientific | 2006 |
| EMJ Concept Limited | Hospitality | 2022 |
| Emma Louise Properties Ltd | Real estate | 2021 |
| Emmankenzoezion Limited | Information & communication | 2021 |
| Emmeness Limited | Construction | 2014 |
| Empire Hire Group Limited | Administrative & support | 2021 |
| Empowered Education Ltd | Education | 2025 |
| Empowered S.M.S. Limited | Information & communication | 2006 |
| Emylan Plumbing Ltd | Construction | 2023 |
| Ena.Reem Ltd | Hospitality | 2024 |
| Encompass Travel Ltd | Administrative & support | 2026 |
| Endeavour Financial Management Limited | Professional & scientific | 2010 |
| Enduo Panoplia Ltd | Wholesale & retail | 2024 |
| Endymion Management Company Limited | Households | 1981 |
| Engineering Contracting Services Ltd | Construction | 2025 |
| Engineering Pipeline Inspection Consultancy (Epic) Services Ltd | Professional & scientific | 2025 |
| Engineering Support Services (GB) Ltd | Construction | 2011 |
| Engineering Techsolution Ltd | Manufacturing | 2025 |
| Enginexport Ltd | Water & waste | 2025 |
| Enlighten Learning Limited | Education | 2025 |
| Enseak Solutions Ltd | Information & communication | 2025 |
| Enter Trans Ltd | Transport & logistics | 2014 |
| Entitle Consulting Limited | Professional & scientific | 2013 |
| Environmental Pipeline Services Limited | Mining & quarrying | 2008 |
| Environmental Pipeline Systems Limited | Extraterritorial | 2014 |
| Epic Cleaning Limited | Administrative & support | 2023 |
| Epic Rigging Ltd | Construction | 2003 |
| Epworth Limited | Hospitality | 2018 |
| EQ Electrics Ltd | Energy | 2021 |
| Equallibriann Recovery Ltd | Wholesale & retail | 2026 |
| Equator Global Ltd | Wholesale & retail | 2024 |
| Equine Wellbeing Management Limited | Other services | 2011 |
| Equinox Nutrition Ltd | Wholesale & retail | 2025 |
| Equity Alliance Ltd. | Real estate | 2013 |
| ER Structures Limited | Construction | 2018 |
| Ergonomic Apps Ltd | Information & communication | 2024 |
| Ergys Car Wash Ltd | Administrative & support | 2023 |
| ERH Consultancy Limited | Professional & scientific | 2026 |
| ERI Roofing Ltd | Construction | 2025 |
| ES Recruitment Services Limited | Administrative & support | 2023 |
| Esda Local Limited | Hospitality | 2020 |
| Esilmas Ltd | Transport & logistics | 2022 |
| Essence Tax Services Ltd | Professional & scientific | 2019 |
| Essence Ventures Group Limited | Administrative & support | 2025 |
| Esseon Limited | Wholesale & retail | 2022 |
| Essity Holding UK Limited | Professional & scientific | 1998 |
| Essity Operations Limited | Professional & scientific | 2012 |
| Essity PLD UK Limited | Wholesale & retail | 2022 |
| Estate Agency Events Ltd | Professional & scientific | 1999 |
| Estovia Ltd | Hospitality | 2024 |
| Etag Construction Fixings Ltd | Wholesale & retail | 2009 |
| Ethical Eggs Limited | Agriculture & fishing | 2021 |
| Ethical Sourcing Ltd | Real estate | 2023 |
| Etigrate Limited | Information & communication | 2010 |
| Euex Limited | Extraterritorial | 2002 |
| Eurasian Munna Limited | Hospitality | 2026 |
| Euro Food Express Ltd | Wholesale & retail | 2025 |
| European Coffee Corporation Limited | Financial services | 1997 |
| EVA Rose Couriers Ltd | Transport & logistics | 2024 |
| Evaoc Ltd | Manufacturing | 2018 |
| Eveboat Health Ltd | Health & social care | 2023 |
| Event Tech Production Services Limited | Professional & scientific | 2019 |
| Eventful GB Ltd | Information & communication | 2009 |
| Eventology Limited | Arts & recreation | 2006 |
| Events by Catalin Iftimie Limited | Arts & recreation | 2018 |
| Evergreen Grass 2020 Ltd | Manufacturing | 2019 |
| Eversholt Green Limited | Professional & scientific | 2012 |
| Evoke and Empowerment Coaching Services Ltd | Administrative & support | 2025 |
| Evoke Ents Limited | Administrative & support | 2021 |
| Evolet Limited | Real estate | 2016 |
| Evolux Development Limited | Construction | 2024 |
| Evolvembed Limited | Construction | 2024 |
| Evolver Solution Ltd | Public administration | 2025 |
| Evolvere Property Group Ltd | Real estate | 2025 |
| Evrepairspecialist Ltd | Wholesale & retail | 2026 |
| Ex-Traordinaryworks Ltd | Manufacturing | 2014 |
| Exact Pest Control Limited | Administrative & support | 2003 |
| Excap Ltd | Financial services | 2013 |
| Excel Vision Limited | Health & social care | 2003 |
| Excelliance Ltd | Professional & scientific | 2015 |
| Excelsoft Ltd | Information & communication | 2020 |
| Exceptional Quality Care Ltd | Health & social care | 2021 |
| Exhibition Travel Services Limited | Administrative & support | 1998 |
| Exmouth Youth Opportunity CIC | Health & social care | 2026 |
| Exotrade Ltd | Wholesale & retail | 2025 |