| Puffin Subsea Engineering Limited | Mining & quarrying | 2012 |
| Pure Red Ltd | Real estate | 2018 |
| PWR Alarm Ltd | Administrative & support | 2025 |
| Q.D. Plastics (Glasgow) Limited | Manufacturing | 1965 |
| Qasd Ltd | Financial services | 2026 |
| Quick N Easy Transport Ltd | Transport & logistics | 2020 |
| R & D Doherty Services Ltd | Administrative & support | 2025 |
| R Campbell Commercials Limited | Water & waste | 2015 |
| Rainey Electrical Ltd | Construction | 2018 |
| RBR Technologies Limited | Professional & scientific | 2011 |
| Red Laing Kitchens Ltd | Manufacturing | 2016 |
| Reed Humidor Ltd | Manufacturing | 2018 |
| Reiam Ltd | Real estate | 2026 |
| Renton Community Development Trust Limited | Health & social care | 2007 |
| Renton Garage Ltd. | Wholesale & retail | 2005 |
| Repay Scotland Limited | Construction | 2017 |
| Reuse IT Limited | Wholesale & retail | 2017 |
| Revo Investments Ltd | Real estate | 2021 |
| Revo Pro Ltd | Information & communication | 2024 |
| RGH Diesel Generator Service Ltd | Extraterritorial | 2021 |
| Rigos Limited | Hospitality | 2008 |
| Ririyou Ltd | Hospitality | 2024 |
| Ritchie Capital Ltd | Financial services | 2026 |
| Robbex FM Limited | Construction | 2018 |
| Robert Macnish & Company Limited | Professional & scientific | 1908 |
| Rock Tandoori Ltd | Hospitality | 2026 |
| ROH Engineering Limited | Professional & scientific | 2013 |
| Rohi Retail Ltd | Wholesale & retail | 2022 |
| Roundabout Inn (Balloch) Ltd. (the) | Hospitality | 1970 |
| RS @ Your Convenience Ltd | Wholesale & retail | 2024 |
| RT Property Services Scotland Ltd | Construction | 2026 |
| Rubato Limited | Real estate | 2000 |
| Runners Cradle Ltd | Wholesale & retail | 2024 |
| S & J Farming Ltd | Agriculture & fishing | 2021 |
| S a a & Sons Ltd | Wholesale & retail | 2024 |
| S.W.G. Lang Ltd | Construction | 2014 |
| S1 Holdings Limited | Professional & scientific | 2016 |
| S1 Storage Limited | Transport & logistics | 2016 |
| Samridhi Limited | Wholesale & retail | 2011 |
| Sandpoint Marina Limited | Transport & logistics | 1995 |
| Savage Engineering Ltd | Manufacturing | 2015 |
| SC138680 Limited | Arts & recreation | 1992 |
| SC849038 Ltd | Wholesale & retail | 2025 |
| School of Football Academy Ltd | Education | 2022 |
| SCO Consultancy Ltd | Professional & scientific | 2026 |
| Scotch Bay Ltd | Wholesale & retail | 2022 |
| Scotechnics Limited | Manufacturing | 1994 |
| Scotfin Limited | Real estate | 2023 |
| Scotlifts Ltd. | Administrative & support | 2009 |
| Scotserve (Bottling Services) Limited | Manufacturing | 1990 |
| Scott Mobile and Gadgets Ltd | Wholesale & retail | 2022 |
| Scottish SKI Club Limited | Arts & recreation | 2025 |
| SD Garage Doors Limited | Construction | 2017 |
| Seaspan Shipping Limited | Transport & logistics | 2004 |
| Selman Marine Design (Scotland) Limited | Professional & scientific | 2014 |
| Sense Property Ltd | Real estate | 2023 |
| Seventeen Creative Ltd | Professional & scientific | 2020 |
| SEW Distill CIC | Manufacturing | 2025 |
| SEW Shire Limited | Manufacturing | 2023 |
| Sfts HV Management Ltd | Construction | 2022 |
| SGC Inspection Ltd | Mining & quarrying | 2022 |
| Shadowglow UK Ltd | Wholesale & retail | 2025 |
| Sharpview Cctv Ltd | Information & communication | 2014 |
| Sheers Well Limited | Real estate | 2022 |
| Shillan Integrity Limited | Professional & scientific | 2024 |
| Showmethedough Ltd | Other services | 2017 |
| Siems Turfgrass Ltd | Administrative & support | 2020 |
| Signature Homes Construction Ltd | Construction | 2025 |
| Silver Star 88 Ltd | Hospitality | 2025 |
| Silverton Chip Shop Limited | Hospitality | 2024 |
| Silverton P.O Services Ltd | Transport & logistics | 2014 |
| Skak Inspection Ltd | Professional & scientific | 2024 |
| Skapade Education CIC | Arts & recreation | 2016 |
| Skapade Ltd | Information & communication | 2018 |
| SKD Restaurant Ltd | Hospitality | 2025 |
| Sky Mobile & Money Transfer Ltd | Wholesale & retail | 2024 |
| SL1 Property Ltd | Real estate | 2022 |
| SLJ Training & Consultancy Ltd | Professional & scientific | 2019 |
| Smart Cookies Academy Ltd | Health & social care | 2025 |
| Smith Engineering (Scotland) Limited | Manufacturing | 2002 |
| Smkm Limited | Administrative & support | 2025 |
| Snug Serviced Apartments LLP | | 2017 |
| Something Special (Whisky) Limited | Professional & scientific | 2016 |
| SP Caravans Ltd | Real estate | 2026 |
| Spark Electrical Scotland Limited | Construction | 2017 |
| Specialist Transport Solutions Limited | Transport & logistics | 2022 |
| SR Clyde Ltd | Wholesale & retail | 2024 |
| SR Property Renovations Ltd | Real estate | 2025 |
| Steel Box Holdings Limited | Transport & logistics | 2021 |
| Stella Marketing Ltd | Professional & scientific | 2023 |
| Steve Pullen Limited | Administrative & support | 2008 |
| Stirling Road Valet Ltd | Wholesale & retail | 2026 |
| Stow Brae Properties Ltd | Real estate | 2024 |
| Strathclyde Distillery Limited | Professional & scientific | 1966 |
| Strathisla Distillery Company Limited | Professional & scientific | 1950 |
| Stretto Limited | Real estate | 2000 |
| Styles by ELM Ltd | Arts & recreation | 2025 |
| Sumit Cleaning Services Limited | Other services | 2018 |
| Sustainedpath AI Limited | Information & communication | 2026 |
| Sweet Solutions Stevia Ltd | Manufacturing | 2012 |